Date Item Type No Grouping

Article

Thermoresponsive engineered emulsions stabilised with branched copolymer surfactants for nasal drug delivery of molecular therapeutics. (2025) Abhishek Rajbanshi, Eleanor Hilton, Emily Atkinson, James B Phillips, Shiva Vanukuru, Vitaliy V Khutoryanskiy, Adam Gibbons, Sabrina Falloon, Cecile A Dreiss, Darragh Murnane and Michael T Cook

Structure, morphology and surface properties of α-lactose monohydrate in relation to its powder properties. (2025) Thai T.H. Nguyen, Cai Y. Ma, Ioanna D. Styliari, Parmesh Gajjar, Robert B. Hammond, Philip J. Withers, Darragh Murnane and Kevin J. Roberts

Stimuli‐Responsive Polymers for Engineered Emulsions. (2024) Abhishek Rajbanshi, Eleanor Hilton, Cécile A. Dreiss, Darragh Murnane and Michael T. Cook

Intranasal Vaccine Formulation: Advancing Towards Nasal Dry Powder Formulation. (2023) Kelvin Forkuoh, Laura Urbano, Laxmi Kerai-Varsani and Darragh Murnane

Microstructural insight into inhalation powder blends through correlative multi-scale X-ray Computed Tomography. (2023) Parmesh Gajjar, Ioanna Danai Styliari, Victoria Legh-Land, Hrishikesh Bale, Benjamin Tordoff, Philip Withers and Darragh Murnane

Branched Copolymer Surfactants as Versatile Templates for Responsive Emulsifiers with Bespoke Temperature‐Triggered Emulsion‐Breaking or Gelation. (2023) Abhishek Rajbanshi, Marcelo Alves da Silva, Niamh Haslett, Philippa Cranwell, Neil Cunningham, Najet Mahmoudi, Darragh Murnane, Ewa Pavlova, Miroslav Slouf, Cecile Dreiss and Michael Cook

Predicting the Strength of Cohesive and Adhesive Interparticle Interactions for Dry Powder Inhalation Blends of Terbutaline Sulfate with α‑Lactose Monohydrate. (2023) Cai Y. Ma, Thai T. H. Nguyen, Parmesh Gajjar, Ioanna D. Styliari, Robert B. Hammond, Philip J. Withers, Darragh Murnane and Kevin J. Roberts

Profiling alveolar macrophage responses to inhaled compounds using in vitro high content image analysis. (2023) Ewelina Hoffman, Laura Urbano, Abigail Martin, Rhamiya Mahendran, Aateka Patel, Darragh Murnane, Clive Page, Lea Ann Dailey, Ben Forbes and Victoria Hutter

Combining branched copolymers with additives generates stable thermoresponsive emulsions with in situ gelation upon exposure to body temperature. (2023) Abhishek Rajbanshi, Najet Mahmoudi, Darragh Murnane, Ewa Pavlova, Miroslav Slouf, Cécile A. Dreiss and Michael T. Cook

Understanding the agglomerate crystallisation of hexamine through X-ray microscopy and crystallographic modelling. (2023) Thai T.H. Nguyen, Parmesh Gajjar, Jun Sun, Robert B. Hammond, Darragh Murnane, Benjamin Tordoff, Erik Lauridsen, Philip J. Withers and Kevin J. Roberts

Development of a New Dislodgeable Foliar Residue Analytical Laboratory Method for Pesticides. (2022) Mohamed Badawy, Darragh Murnane, Kathy Lewis and Neil Morgan

Polymer architecture dictates thermoreversible gelation in engineered emulsions stabilised with branched copolymer surfactants. (2022) Abhishek Rajbanshi, Marcelo Alves da Silva, Darragh Murnane, Lionel Porcar, Cécile A. Dreiss and Michael T. Cook

High Content Image Analysis as a Tool to Morphologically Distinguish Macrophage Activation and Determine Its Importance for Foamy Alveolar Macrophage Responses. (2021) Ewelina Hoffman, Paulina Napieralska, Rhamiya Mahendran, Darragh Murnane and Victoria Hutter

Solid-phase microextraction for assessment of plasma protein binding, a complement to rapid equilibrium dialysis. (2021) Ahmad, Sheelan, Daniel Baker, Darragh Murnane, Spooner, Neil and Ute Gerhard

Water Uptake by Evaporating pMDI Aerosol Prior to Inhalation Affects Both Regional and Total Deposition in the Respiratory System. (2021) Victoria Legh-Land, Allen E. Haddrell, David Lewis, Darragh Murnane and Jonathan P. Reid

Crystallographic tomography and molecular modelling of structured organic polycrystalline powders. (2021) Parmesh Gajjar, Thai T. H. Nguyen, Jun Sun, Ioanna D. Styliari, Hrishikesh Bale, Samuel A. McDonald, Timothy L. Burnett, Benjamin Tordoff, Erik Lauridsen, Robert B. Hammond, Darragh Murnane, Philip J. Withers and Kevin J. Roberts

The influence of oily vehicle composition and vehicle-membrane interactions on the diffusion of model permeants across barrier membranes. (2021) Omaima N. Najib, Gary P. Martin, Stewart B. Kirton, Michelle J. Botha, Al Sayed Sallam and Darragh Murnane

Multivariate analytical approaches to identify key molecular properties of vehicles, permeants and membranes that affect permeation through membranes. (2020) Omaima N. Najib, Stewart B. Kirton, Gary P. Martin, Michelle J. Botha, Al Sayed Sallam and Darragh Murnane

3D Characterisation of Dry Powder Inhaler Formulations: Developing X-ray Micro Computed Tomography Approaches. (2020) P Gajjar, I D Styliari, T T H Nguyen, J Carr, X Chen, J A Elliott, R B Hammond, T L Burnett, K Roberts, P J Withers and D Murnane

A digital workflow from crystallographic structure to single crystal particle attributes for predicting the formulation properties of terbutaline sulfate. (2020) Thai T. H. Nguyen, Robert B. Hammond, Ioanna D. Styliari, Darragh Murnane and Kevin J. Roberts

Investigating the suitability of high content image analysis as a tool to assess the reversibility of foamy alveolar macrophage phenotypes in vitro. (2020) Ewelina Hoffman, Darragh Murnane and Victoria Hutter

Wurster fluidised bed coating of microparticles: Towards scalable production of oral sustained-release liquid medicines for patients with swallowing difficulties. (2019) Valentyn Mohylyuk, Kavil Patel, Nathan Scott, Darragh Murnane and Fang Liu

Development of an adaptive bypass element for passive entrainment flow control in dry powder inhalers. (2019) Thomas Kopsch, Darragh Murnane and Digby Symons

Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis. (2019) Aateka Bodhaniya, Ewelina Hoffman, Dough Ball, Jan Klapwijk, Rory T. Steven, Alex Dexter, Josephine Bunch, Daniel Baker, Darragh Murnane, Victoria Hutter, Clive Page, Lea Ann Dailey and Ben Forbes

‘Great ease and simplicity of action’: Dr Nelson’s Inhaler and the origins of modern inhalation therapy. (2017) Barry Murnane, Darragh Murnane, Mark Sanders and Noel Snell

A personalized medicine approach to the design of dry powder inhalers: : Selecting the optimal amount of bypass. (2017) Thomas Kopsch, Darragh Murnane and Digby Symons

Dispersing the Mists: An Experimental History of Medicine Study into the Quality of Volatile Inhalations. (2017) Barry Murnane, Cathal Gallagher, Noel Snell, Mark Sanders, Ramin Moshksar and Darragh Murnane

Predicting the Fine Particle Fraction of Dry Powder Inhalers Using Artificial Neural Networks. (2017) Joanna Muddle, Stewart B. Kirton, Irene Parisini, Andrew Muddle, Darragh Murnane, Jogoth Ali, Marc Brown, Clive Page and Ben Forbes

Optimizing the Entrainment Geometry of a Dry Powder Inhaler : Methodology and Preliminary Results. (2016) Thomas Kopsch, Darragh Murnane and Digby Symons

Establishing the importance of oil-membrane interactions on the transmembrane diffusion of physicochemically diverse compounds. (2016) Omaima N. Najib, Gary P Martin, Stewart Kirton, Al-Sayed Sallam and Darragh Murnane

Mathematical approach for understanding deagglomeration behaviour of drug powder in formulations with coarse carrier. (2015) Irene Parisini, James L. Collett and Darragh Murnane

Direct Ionization of Solid-Phase Microextraction Fibers for Quantitative Drug Bionalysis : From Peripheral Circulation to Mass Spectrometry Detection. (2015) Ahmad, Sheelan, Tucker, Michael, Spooner, Neil, Darragh Murnane and Ute Gerhard

Formulation pre-screening of inhalation powders using computational atom-atom systematic search method. (2015) Vasuki Ramachandran, Darragh Murnane, Robert B. Hammond, Jonathan Pickering, Kevin J. Roberts, Majeed Soufian, Ben Forbes, Sara Jaffari, Gary P. Martin, Elizabeth Collins and Klimentina Pencheva

Evidence for the existence of powder sub-populations in micronized materials : Aerodynamic size-fractions of aerosolized powders possess distinct physicochemical properties. (2014) Sara Jaffari, Ben Forbes, Elizabeth Collins, Jiyi Khoo, Gary P. Martin and Darragh Murnane

Potential of a cyclone prototype spacer to improve in vitro dry powder delivery. (2014) Irene Parisini, Sean J Cheng, Digby Symons and Darragh Murnane

Dynamics of aerosol size during inhalation : Hygroscopic growth of commercial nebulizer formulations. (2014) Allen E. Haddrell, James F. Davies, Rachael E. H. Miles, Jonathan P. Reid, Lea Ann Dailey and Darragh Murnane

Rapid characterisation of the inherent dispersibility of respirable powders using dry dispersion laser diffraction. (2013) Sara Jaffari, Ben Forbes, Elizabeth Collins, David J. Barlow, Gary P. Martin and Darragh Murnane

Nitrogen-14 Nuclear Quadrupole Resonance Spectroscopy: : a powerful new analytical methodology for medicines authentication and counterfeit antimalarial analysis. (2013) Jamie Barras, Darragh Murnane, Kaspar Althoefer, Sulaf Assi, MIchael D. Rowe, Iain J. F. Poplett, Georgia Kyriakidou and John A. S. Smith

Concordance, adherence or competence – device use and therapeutic outcomes in older patients. (2013) Darragh Murnane

Characterization of latent heat-releasing phase change materials for dermal therapies. (2011) D.G. Wood, Marc Brown, S. A. Jones and D. Murnane

Investigations into the formulation of metered dose inhalers of salmeterol xinafoate and fluticasone propionate microcrystals. (2008) Darragh Murnane, Gary P. Martin and Christopher Marriott

In situ and Ex situ analysis of salmeterol xinafoate microcrystal formation from poly(ethylene glycol) 400 - Water cosolvent mixtures. (2008) Darragh Murnane, Christopher Marriott and Gary P. Martin

Developing an environmentally benign process for the production of microparticles : Amphiphilic crystallization. (2008) Darragh Murnane, Christopher Marriott and Gary P. Martin

Validation of a reverse-phase high performance liquid chromatographic method for concurrent assay of a weak base (salmeterol xinafoate) and a pharmacologically active steroid (fluticasone propionate). (2006) D Murnane, G P Martin and C Marriott

Comparison of salmeterol xinafoate microparticle production by conventional and novel antisolvent crystallization. (2008) Darragh Murnane, Christopher Marriott and Gary P. Martin

Polymorphic control of inhalation microparticles prepared by crystallization. (2008) Darragh Murnane, Christopher Marriott and Gary P. Martin

Dry Powder Formulations for Inhalation of Fluticasone Propionate and Salmeterol Xinafoate Microcrystals. (2009) Darragh Murnane, Gary P. Martin and Christopher Marriott

Formation and measurement of process induced disorder during the manufacture of inhalation medicines. (2011) P.G. Royall, B. Woodhead, S.J. Tang, G.P. Martin, B.M. Stockton and D. Murnane

Interaction of Formulation and Device Factors Determine the In Vitro Performance of Salbutamol Sulphate Dry Powders for Inhalation. (2015) Joanna Muddle, Darragh Murnane, Irene Parisini, Marc Brown, Clive Page and Ben Forbes

Conference or Workshop Item

Unlocking the Microstructure of Inhalation Blends using X-ray Microscopy. (2020) Parmesh Gajjar, Hrishikesh Bale, Timothy Burnett, Xizhong Chen, James A. Elliot, Herminso Villarraga Gomez, Robert B. Hammond, Hien Nguyen, Kevin J. Roberts, Ioanna Danai Styliari, Benjamin Tordoff, Philip Withers and Darragh Murnane

Molecular Synthon Modelling Of Inhalation Pharmaceuticals: A Digital Approach To Understanding And Engineering Particle Surface Interactions. (2020) Thai T. H. Nguyen, Robert Hammond, Ioanna Danai Styliari, Darragh Murnane and Kevin J. Roberts

On Measuring the Specific Surface Area of inhalation-grade lactose powders. (2020) Ioanna Danai Styliari, Thai TH Nguyen, Parmesh Gajjar, Benjamin Tordoff, Timothy Burnett, Philip Withers, Robert B. Hammond, Kevin J. Roberts and Darragh Murnane

Multiscale Tomography: Probing The Nano-, Micro-, And Meso-Scale Resolution Of Inhalation Powder Structure. (2019) Parmesh Gajjar, Ioanna Danai Styliari, Timothy Burnett, Xizhong Chen, James A. Elliot, William J. Ganley, Robbert Hammond, Hien Nguyen, Robert Price, Kevin Roberts, Philip Withers and Darragh Murnane

Physicochemical characterisation of inhalation grade lactose after the removal of intrinsic fines. (2018) Ioanna Danai Styliari, Arian Mobli and Darragh Murnane

Book

Proceedings of Abstracts, School of Physics, Engineering and Computer Science Research Conference 2022. (2022) Daerefa-a Amafabia, Laurel Asimea, John Bally, Anthony Baran, Adam Boies, Amirhossein Borjali, Chloe Bosomworth, Ben Burningham, Napoleana-Anna Chaliasou, Yong Kang CHEN, Yuen Ki Cheong, Mahmoud Chizari, Etelka Chung, Kristen Coppin, Opukuro David-West, Nik Dennler, Hom Dhakal, Nikolay Dimov, Emil Dmitruk, Allen Donald, Damien Drix, Sergio A. Dzib, Mahmoud Eltaweel, Sajid Fadlelseed, Atena Farahani, Adrian Felix, Tim Foat, Jan Forbrich, Maximilien Franco, Joesphine Gaarn, Tracy Garratt, Jim Geach, Narges Ghias, Adrian Ghita, Niccolo Giannetti, Jaime Vargas-Gonzalez, Richard Greenaway, George Haritos, Sara Hatami, David Haydock, Na Helian, Mohammad Reza Herfatmanesh, Jean-Baptiste Herve, Evelyn Hesse, Hossein Korani, Vahid Hosseini, Wei Hu, Thomas Hubbard, Jameel Inal, Patrick Irigo, Sikiru O. Ismail, Fiona Jepleting, Wei Ji, Ian Johnston, Gbanaibolou Jombo, Shabnam Kadir, Christos Kalyvas, Syed Muhammad Kamran, Antonios Kanellopoulos, Aklil Zenebe Kiflay, Raimund Kirner, Kerry Knox, Chiaki Kobayashi, Dhirendra Kumar, Ritesh Kumar, Peter Lane, Himayasri Lekkala, Andrew Lewis, Liang Li, Qi Luo, Hossein Madani, Colin Mallet, Surya Maruthupandian, Elizabeth Reeja Mathen, Pavel Matousek, Simon McCool, James C. McGarry, Catherine Menon, Christoph Metzner, Rachael E. H. Miles, Hadi Moeinnia, Paul Moggridge, Mahdi Mohseni, Diogo Montalvão, Mohammad Najeeb Moraby, Darragh Murnane, Marc Norgate, Amir Nourani, Kumar Shantanu Prasad, Soodamani Ramalingam, Shavika Rastogi, Jonathan P. Reid, Guogang Ren, Victor M. Rivilla, Hossein Saidpour, Kiyoshi Saito, Seyed Amir Hossein Sajedi, Christoph Salge, Samadhi Samararatne, Michael Schmuker, Elif Sensoy, Ajay Shriram, Harpreet Singh, Yasser Sorouraddin, Volker Steuber, Nicholas Stone, Yi Sun, Roopesh Sureddi, Samuel Sutton, Peter Thomas, Andrew R Timms, P. R. Tiwari, Athanasios Tsokanos, Mansukhlal Vadalia, Muhammad Yaqoob, Muhamad Yulianto and Minghua Zheng

Other

Particle aggregation of salmeterol xinafoate (SX) in HFA134a high pressure suspensions. (2006) D. Murnane, G.P. Martin and C. Marriott

Evidence for flocculation-controlled microcrystallisation of salmeterol xinafoate. (2006) D. Murnane, G.P. Martin, I. Haley and C. Marriott

Investigation of a reverse-phase high performance liquid chromatography (RP-HPLC) method for a weakly basic drug. (2005) D. Murnane, G. P. Martin and C. Marriott

Transiently supersaturated solutions from the dissolution of amorphous powders for topical drug delivery. (2010) I. A. Palmer, S. A. Jones, D. Murnane, M.J. Traynor, Gary Moss and Marc Brown

The effect of aerodynamic particle size and solid state disorder on salmeterol xinafoate deposition from pressurised metered dose and dry powder inhaler formulations. (2013) S. Jaffari, G. Sandhu, G. P. Martin, B. Forbes, E. Collins and D. Murnane

Assessment of a cyclone-type spacer device for use in dry powder inhalation. (2013) I. Parisini, S. J. Cheng, D. D. Symons, Marc Brown, A. Kostrzewski and D. Murnane