Author

Number of items: 74.
Article
  • Inhibition of levodopa-induced abnormal involuntary movements (AIMs) using a selective α7 nicotinic positive allosteric modulator. (2026) Yasaman Malekizadeh, Kiana Hassankhani, Alice E Kingslake, Lucy E Annett, Mohammed Shoaib and Mahmoud M Iravani
  • Contrasting Behavioural and Biochemical Characteristics of Normal and Spontaneously α‐Synuclein‐Deficient Mice Treated With MPTP. (2025) W. H. Powell, A. Ghita, F. C. Pascut, K. F. Webb, A. Newman‐Tancredi and M. M. Iravani
  • Dysregulation of epithelial ion transport and neurochemical changes in the colon of a parkinsonian primate. (2021) Erika Coletto, Ian Tough, Sara Pritchard, Atsuko Hikima, Michael Jackson, Peter Jenner, K. Ray Chaudhuri, Helen Cox, Mahmoud Iravani and Sarah Rose
  • Contractile dysfunction and nitrergic dysregulation in small intestine of a primate model of Parkinson’s disease : contractile dysfunction in MPTP-treated primate ileum. (2019) E Coletto, John S Dolan, Sara Pritchard, Alex Gant, Atsuko Hikima, Michael J Jackson, Christopher Benham, K. Ray Chaudhuri, Sarah Rose, Peter Jenner and Mahmoud Iravani
  • Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease. (2017) Michel Modo, William R Crum, Madeline Gerwig, Anthony C Vernon, Priya Patel, Michael J Jackson, Sarah Rose, Peter Jenner and Mahmoud M Iravani
  • Altered detrusor contractility in MPTP-treated common marmosets with bladder hyperreflexia. (2017) Sara Pritchard, Atsuko Hikima, Michael Jackson, Lisa Lione, Christopher Benham, K. Ray Chaudhuri, Sarah Rose, Peter Jenner and Mahmoud Iravani
  • Loss of locus coeruleus noradrenergic neurons alters the inflammatory response to LPS in substantia nigra but does not affect nigral cell loss. (2014) Mahmoud M. Iravani, Mona Sadeghian, Sarah Rose and Peter Jenner
  • Lipopolysaccharide-induced nigral inflammation leads to increased IL-1β tissue content and expression of astrocytic glial cell line-derived neurotrophic factor. (2012) Mahmoud M. Iravani, Mona Sadeghian, Clement C. M. Leung, Peter Jenner and Sarah Rose picture_as_pdf
  • Striatal plasticity in Parkinson's disease and L-DOPA induced dyskinesia. (2012) Mahmoud M. Iravani, Andrew C. McCreary and Peter Jenner picture_as_pdf
  • Mechanisms underlying the onset and expression of levodopa-induced dyskinesia and their pharmacological manipulation. (2011) Mahmoud M. Iravani and Peter Jenner picture_as_pdf
  • The effect of nNOS inhibitors on toxin-induced cell death in dopaminergic cell lines depends on the extent of enzyme expression. (2011) Monika J. Brzozowski, Susana Lopez Alcantara, Mahmoud M. Iravani, Sarah Rose and Peter Jenner picture_as_pdf
  • Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia. (2010) Bai-Yun Zeng, Mahmoud M. Iravani, Michael J. Jackson, Sarah Rose, Andre Parent and Peter Jenner picture_as_pdf
  • Continuous rotigotine administration reduces dyskinesia resulting from pulsatile treatment with rotigotine or L-DOPA in MPTP-treated common marmosets. (2010) K. A. Stockwell, D. K. A. Scheller, L. A. Smith, S. Rose, Mahmoud M. Iravani, M. J. Jackson and P. Jenner picture_as_pdf
  • Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction. (2009) K. A. Stockwell, D. Scheller, S. Rose, M. J. Jackson, K. Tayarani-Binazir, Mahmoud M. Iravani, L. A. Smith, C. W. Olanow and P. Jenner picture_as_pdf
  • An immunohistochemical and stereological analysis of PSI-induced nigral neuronal degeneration in the rat. (2009) Salma Bukhatwa, Mahmoud M. Iravani, Bai-Yun Zeng, Jonathan D. Cooper, Sarah Rose and Peter Jenner picture_as_pdf
  • Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response. (2008) Mahmoud M. Iravani, Mona Sadeghian, Clement C. M. Leung, Banu C. Tel, Sarah Rose, Anthony H. Schapira and Peter Jenner picture_as_pdf
  • Proteasomal abnormalities in cortical Lewy body disease and the impact of proteasomal inhibition within cortical and cholinergic systems. (2008) Nicholas MacInnes, Mahmoud M. Iravani, Elaine Perry, Margaret Piggott, Robert Perry, Peter Jenner and Clive Ballard picture_as_pdf
  • Continuous delivery of ropinirole reverses motor deficits without dyskinesia induction in MPTP-treated common marmosets. (2008) K. A. Stockwell, D. J. Virley, M. Perren, Mahmoud M. Iravani, M. J. Jackson, S. Rose and P. Jenner picture_as_pdf
  • Neuropeptide Y in rat detrusor and its effect on nerve-mediated and acetylcholine-evoked contractions. (1994) Mahmoud M. Iravani and M. A. Zar
  • Pramipexole protects against MPTP toxicity in non-human primates. (2006) Mahmoud M. Iravani, C. O. Haddon, J. M. Cooper, P. Jenner and A. H. Schapira
  • Involvement of inducible nitric oxide synthase in inflammation-induced dopaminergic neurodegeneration. (2002) Mahmoud M. Iravani, K. Kashefi, P. Mander, S. Rose and P. Jenner
  • GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed common marmosets. (2001) Mahmoud M. Iravani, S. Costa, M. J. Jackson, Banu C. Tel, C. Cannizzaro, R. K. B. Pearce and P. Jenner
  • Glial cell line-derived neurotrophic factor concentration dependently improves disability and motor activity in MPTP-treated common marmosets. (2001) S. Costa, Mahmoud M. Iravani, R. K. B. Pearce and P. Jenner
  • Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or dopamine release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulate, and the dorsal raphe nucleus slices. (2000) Mahmoud M. Iravani, D. Asari, J. Patel, W. J. Wieczorek and Z. L. Kruk
  • Effects of amphetamine on carrier-mediated and electrically stimulated dopamine release in slices of rat caudate-putamen abd nucleus-accumbens. (1995) Mahmoud M. Iravani and Z. L. Kruk
  • Effect of Nifedipine on the contractile responses of the isolated rat bladder. (1990) M. A. Zar, Mahmoud M. Iravani and G. N. Luheshi
  • The H3 receptor agonist immepip does not affect l-dopa-induced abnormal involuntary movements in 6-OHDA-lesioned rats. (2014) Maria Papathanou, Peter Jenner, Mahmoud M. Iravani, Michael Jackson, Kim Stockwell, Isobel Strang, Bai-Yun Zeng, Andrew McCreary and Sarah Rose
  • Differential release of dopamine by nitric oxide in subregions of rat caudate putamen slices. (1998) Mahmoud M. Iravani, J. Millar and Z. L. Kruk
  • Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms. (2004) M. Gu, Mahmoud M. Iravani, J.M. Cooper, Diane King, P. Jenner and A. H. V. Schapira
  • In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates, the selective 5-hydroxytryptamine 1a agonist (R)-(+)-8-OHDPAT inhibits levodopa-induced dyskinesia but only with\increased motor disability. (2006) Mahmoud M. Iravani, Kayhan Tayarani-Binazir, Wing B. Chu, Michael J. Jackson and Peter Jenner
  • MPTP treatment of common marmosets impairs proteasomal enzyme activity and decreases expression of structural and regulatory elements of the 26S proteasome. (2006) Bai-Yun Zeng, Mahmoud M. Iravani, S. T. Lin, M. Irifune, M. Kuoppamaki, G. Al-Barghouthy, L. Smith, M. J. Jackson, S. Rose, A.D. Medhurst and P. Jenner
  • 3-Nitrotyrosine-dependent dopaminergic neurotoxicity following direct nigral administration of a peroxynitrite but not a nitric oxide donor. (2006) Mahmoud M. Iravani, C. O. Haddon, S. Rose and P. Jenner
  • Unilateral pallidotomy in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets exhibiting levodopa-induced dyskinesia. (2005) Mahmoud M. Iravani, S. Costa, G. Al-Bargouthy, M. J. Jackson, Bai-Yun Zeng, M. Kuoppamaki, J. A. Obeso and P. Jenner
  • Age-associated changes in protein oxidation and proteasome activities in rat brain: Modulation by antioxidants. (2005) M. M. A. El Mohsen, Mahmoud M. Iravani, J. P. E. Spencer, S. Rose, A. T. Fahim, T. M. K. Motawi, N. A. F. Ismail and P. Jenner
  • The acute and the long-term effects of nigral lipopolysaccharide administration on dopaminergic dysfunction and glial cell activation. (2005) Mahmoud M. Iravani, Clement C. M. Leung, Mona Sadeghian, C. O. Haddon, Sarah Rose and P. Jenner
  • Sonic hedgehog delivered by an adeno-associated virus protects dopaminergic neurones against 6-OHDA toxicity in the rat. (2005) B. Dass, Mahmoud M. Iravani, C. Huang, J. Barsoum, T. M. Engber, A. Galdes and P. Jenner
  • A modified MPTP treatment regime produces reproducible partial nigrostriatal lesions in common marmosets. (2005) Mahmoud M. Iravani, E. Syed, M. J. Jackson, L. C. Johnston, L. A. Smith and P. Jenner
  • Role of inducible nitric oxide synthase in N-methyl-D-aspartic acid-induced strio-nigral degeneration. (2004) Mahmoud M. Iravani, L. Liu, S. Rose and P. Jenner
  • Real-time effects of N-methyl-D-aspartic acid on dopamine release in slices of rat caudate putamen : A study using fast cyclic voltammetry. (1996) Mahmoud M. Iravani and Z. L. Kruk
  • 3,4-methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates. (2003) Mahmoud M. Iravani, M. J. Jackson, M. Kuoppamaki, L. A. Smith and P. Jenner
  • Behavioural and immunohistochemical changes following supranigral administration of sonic hedgehog in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets. (2002) B. Dass, Mahmoud M. Iravani, M. J. Jackson, T. M. Engber, A. Galdes and P. Jenner
  • Real-time measurement of stimulated 5-hydroxytryptamine release in rat substantia nigra pars reticulata brain slices. (1997) Mahmoud M. Iravani and Z. L. Kruk
  • The presence and the effects of neuropeptide Y in rat anococcygeus muscle. (1997) Mahmoud M. Iravani and M. A. Zar
  • The role of ventral tegmental dopamine neurons in locomotor sensitization following quinpirole or (+)-amphetamine : Ex vivo voltammetric evidence. (1996) R. Muscat, Mahmoud M. Iravani and Z. L. Kruk
  • Comparison of somatodendritic and axon terminal dopamine release in the ventral tegmental area and the nucleus accumbens. (1996) Mahmoud M. Iravani, R. Muscat and Z. L. Kruk
  • Presence of Neuropeptide-y in the rat seminal-vesicle and its effects on Noradrenaline-induced and nerve-induced contractions. (1994) Mahmoud M. Iravani and M. A. Zar
    • Conference or Workshop Item
  • MicroRNA and gene expression profiles in a Parkinson’s disease cell model. (2023) Paul Moran, Braoudaki Maria and Mahmoud Iravani
  • Neuroprotective properties of arylpiperazine-sulphonamides in in vitro models of Parkinson's disease. (2023) Alice Kingslake, Vukic Soskic and Mahmoud Iravani
  • The neuroprotective properties of NLX-112 in MPTP treated mice are mediated by reactive gliosis and astrocytic GDNF. (2023) William Powell, Ronan Depoortere, Lucy Annett, Adrian Newman-Tancredi and Mahmoud Iravani
  • Alpha7 nicotinic receptor- mediated reduction of L-DOPA-induced dyskinesia in 6OHDA rat model of Parkinson’s Disease. (2023) Yasaman Malekizadeh, Kiana Hassankhani, Alice Kingslake, Lucy Annett, Mohammed Shoaib and Mahmoud Iravani
  • Effect of alpha-4 beta-2 nicotinic acetylcholine receptors on L-DOPA-induced dyskinesia in 6OHDA rat model of Parkinson’s Disease. (2023) Kiana Hassankhani, Alice Kingslake, Yasaman Malekizadeh, Lucy Annett, Mahmoud Iravani and Mohammed Shoaib
    • Patent
  • Inhibition or Treatment of Dyskinesia. (2006) Mahmoud M. Iravani and Peter Jenner
    • Other
  • NMDA releases a nitric oxide-like substance in rat striatum : a study using fast cyclic voltammetry. (1994) Mahmoud M. Iravani, J. Millar and Z. L. Kruk
  • Differential-effects of Nifedipine on nerve-mediated and noradrenaline-evoked contractions of rat anococcygeus muscle. (1993) Mahmoud M. Iravani and M. A. Zar
  • The effect of exercise and heart rate on fibrinolytic activity. (1993) H. A. Dewar, M. A. Zar, N. M. Smith, Mahmoud M. Iravani and R. Stappenbeck
  • Effect of NMDA receptor blockade on dopamine overflow in rat caudate putamen. (1992) Mahmoud M. Iravani and Z. L. Kruk
  • Effect of frequency of stimulation on neurogenic responses of isolated rat epidymal vas deferens. (1987) Mahmoud M. Iravani and M. A. Zar
  • Occurrence and distribution of neuropeptide Y (NPY)-immunoreactive nerves in rat isolated anococcygeus, and the effect of NPY on the inhibitory transmission. (1987) Mahmoud M. Iravani, J. R. McDermott, J. D. Turner and M. A. Zar
  • Electrochemical detection of dopamine and nitric-oxide in-vitro and in rat corpus striatum : a study using fast cyclic voltammetry with a sinusoidal drive wave-form. (1994) Mahmoud M. Iravani, J. Millar and Z. L. Kruk
  • Variations in evoked Dopamine overflow within the rat striatum measured using fast cyclic voltammetry. (1991) Mahmoud M. Iravani and Z. L. Kruk
  • Differential sensitivities of rat striatal D-2 Dopamine autoreceptor sites. (1992) Mahmoud M. Iravani and Z. L. Kruk
  • Dopamine releasing actions of NMDA in rat caudate putamen studied by fast cyclic voltammetry. (1992) Mahmoud M. Iravani and Z. L. Kruk
  • Evidence for neuropeptide-Y (NPY) as the probable non-cholinergic motor transmitter in rat urinary-bladder in vitro. (1988) Mahmoud M. Iravani and M. A. Zar
  • Inhibition of non-cholinergic motor transmission in isolated rat urinary-bladder by nifedipine. (1988) Mahmoud M. Iravani, G. N. Luheshi and M. A. Zar
  • MK-801 interaction with the 5-HT transporter : A real-time study in brain slices using fast cyclic voltammetry. (1999) Mahmoud M. Iravani, R. Muscat and Z. L. Kruk
  • Physiological and Functional Changes in the Colon of MPTP-Treated Common Marmosets. (2014) Erika Coletto, Ian Tough, Atsuko Hikima, Mahmoud M. Iravani, K. Ray Chaudhuri, Peter Jenner, Helen Cox and Sarah Rose
  • Increase in the number of striatal neuronal nitric oxide synthase immunoreactive (nNOS-ir) interneurones in MPTP-treated common marmosets primed for and displaying levodopa-induced dyskinesia. (2013) Megawate Peeris, Luiza Geraldes, Michael Jackson, Atsuko Hikima, Martin Broadstock, Sarah Rose, Peter Jenner and Mahmoud M. Iravani
  • The effects of pallidotomy on motor function in MPTP-treated, L-DOPA primed common marmosets. (2004) S. S. Costa, Mahmoud M. Iravani, M. J. Jackson and P. Jenner
  • The spontaneous and neurogenic contractile responses of the isolated bladder smooth muscle are markedly enhanced in MPTP treated common marmoset (Callithrix jacchus). (2013) Sara Pritchard, Michael Jackson, Lisa Lione, Christopher Benham, Sarah Rose, Peter Jenner and Mahmoud M. Iravani
  • Continuous vs pulsatile administration of rotigotine in rat and monkey models of Parkinson's disease: A comparison. (2008) D. K. A. Scheller, W. J. Schmidt, M. J. Jackson, U. Ruess, K. Stockwell, M. Heindl, Mahmoud M. Iravani, K. Tayarani-Binazir, S. Rose and P. Jenner
  • Ecstasy (3,4-Methylenedioxymethamphetamine) inhibits dyskinesia expression and normalises locomotor activity in parkinsonian primates. (2002) Mahmoud M. Iravani, M. J. Jackson, G. Al-Barghouthy, M. Kouppamaki and P. Jenner
  • The effect of unilateral pallidotomy on motor disability, and L-dopa-induced dyskinesia in parkinsonian marmosets. (2002) Mahmoud M. Iravani, S. Costa, M. J. Jackson, G. Al-Bargouthy and P. Jenner
  • Heterogeneous effects of NMDA on dopamine release in the rat caudate-putamen. (1995) Mahmoud M. Iravani and Z. L. Kruk
  • Effects of 6-Hydroxydopamine lesions in the ventral tegmental area or substantia-nigra on dopamine release in subregions of the rat striatum. (1995) Mahmoud M. Iravani, S. Khan, A. Michaeltitus, R. Whelpton and Z. L. Kruk