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Now showing items 31-40 of 54
Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis : experience in the ERAN inception cohort
(2013-05)
Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors ...
Can simvastatin improve erectile function and health-related quality of life in men aged ≥40 years with erectile dysfunction? : Results of the Erectile Dysfunction and Statins Trial [ISRCTN66772971]
(2013-01-29)
To evaluate the effectiveness and cost-effectiveness of simvastatin on erectile function and health-related quality of life in men aged ≥40 years with erectile dysfunction (ED).
Measuring and modelling occupancy time in NHS continuing healthcare
(2011)
Due to increasing demand and financial constraints, NHS continuing healthcare systems seek to find better ways of forecasting demand and budgeting for care. This paper investigates two areas of concern, namely, how long ...
Developing a dyadic OPTION scale to measure perceptions of shared decision making
(2010)
Our aim was to develop a measurement which enables research into the interdependent nature of clinical encounters. The prime objective was to develop an instrument capable of assessing the extent to which patients have ...
Dementia, dignity and quality of life : nursing practice and its dilemmas
(2010)
The need for healthcare practitioners to respect the dignity of older people is widely recognised in England, where it has been given attention by politicians, professionals and health service regulators. This article aims ...
Revascularization versus medical therapy for renal-artery stenosis
(2009)
Atherosclerotic renovascular disease is a common condition with a rate of death of about 16% per year, largely from associated cardiovascular disease.1-3 Stenosis of the renal artery is associated with both hypertension ...
Colorectal tumor vascularity: quantitative assessment with multidetector CT--do tumor perfusion measurements reflect angiogenesis?
(2008)
To establish the relationships between quantitative perfusion computed tomography (CT) parameters-specifically, primary tumor blood flow, blood volume, transit time, and permeability surface-area product-and immunohistologic ...
Quantitative assessment of colorectal cancer tumor vascular parameters by using perfusion CT: influence of tumor region of interest
(2008)
To prospectively determine whether position and size of tumor region of interest (ROI) influence estimates of colorectal cancer vascular parameters at computed tomography (CT).
Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons
(2008)
Cannabinoid receptor 2 (CB2) agonists provide the potential for treating chronic pain states without CNS effects associated with CB1 receptor activation. Animal models suggest that they act mainly via non-neuronal cells, ...