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Browsing by Author "Centre for Lifespan and Chronic Illness Research"
Now showing items 21-40 of 153
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Can Early, Clinically Significant Radiographic Progression In The First Year Of Disease Predict Orthopaedic Surgery In Patients With Rheumatoid Arthritis?
Carpenter, Lewis; Jayakumar, Keeranur; Nikiphorou, Elena; Norton, Sam; Dixey, Josh; Young, Adam (2014-04)BACKGROUND: Orthopaedic intervention is an important outcome in Rheumatoid Arthritis (RA). The use of radiographic data in the early stages of the disease and its importance in determining future RA related outcomes is ... -
Can perfusion CT assessment of primary colorectal adenocarcinoma blood flow at staging predict for subsequent metastatic disease? A pilot study
Goh, V.; Halligan, S.; Wellsted, D.; Bartram, C.I. (2009)We aimed to determine whether perfusion CT measurements at colorectal cancer staging may predict for subsequent metastatic relapse. Fifty two prospective patients underwent perfusion CT at staging to estimate tumour blood ... -
Can simvastatin improve erectile function and health-related quality of life in men aged over 40 years with erectile dysfunction? : Rationale and design of the Erectile Dysfunction and Statins (EDS) Trial [ISRCTN66772971]
Trivedi, Daksha; Kirby, Michael; Norman, Felicity; Przybytniak, Izabela; Ali, Shehzad; Wellsted, D. (2011-12-01)OBJECTIVE To describe the rationale and design of the Erectile Dysfunction and Statins (EDS) Trial which aims to evaluate the effectiveness of simvastatin on erectile function and health-related quality of life in men aged ... -
Can simvastatin improve erectile function and health-related quality of life in men aged ≥40 years with erectile dysfunction? : Results of the Erectile Dysfunction and Statins Trial [ISRCTN66772971]
Trivedi, Daksha; Kirby, Michael; Wellsted, D.; Ali, Shehzad; Hackett, Geoff; O'Connor, Bernadette; Van Os, Sandra (2013-01-29)To evaluate the effectiveness and cost-effectiveness of simvastatin on erectile function and health-related quality of life in men aged ≥40 years with erectile dysfunction (ED). -
Can simvastatin improve erectile function and quality of life in men with erectile dysfunction?
Trivedi, Daksha; Kirby, Michael; Norman, Felicity; Przybytniak, Izabela; Ali, Shehzad; Wellsted, D. (2011) -
Cerebral lateralization is delayed in children who later develop schizophrenia
Crow, T.J.; Done, D.J.; Sacker, A. (1996)The origins of schizophrenia are obscure. One suggestion is that it represents a component of the genetic variation associated with the establishment of dominance in one or other cerebral hemisphere, a mechanism that has ... -
Childhood precursors of psychosis as clues to its evolutionary origins
Crow, T.J.; Done, D.J.; Sacker, A. (1995)Those who as adults will be admitted to a psychiatric ward with a psychotic illness can be distinguished (on the basis of group differences) from others by their behaviour and academic performance at he ages of 7 and 11 ... -
Children's physical activity assessed with wrist- and hip-worn accelerometers
Rowlands, Alex; Rennie, Kirsten; Kozarski, Robert; Stanley, Rebecca; Eston, Roger; Parfitt, Gaynor; Olds, Tim (2014-12)Recently, triaxial raw acceleration accelerometers have become available from GENEActiv and ActiGraph; both are designed for wrist and hip wear. It is important to determine whether the output from these monitors is ... -
Choosing Not to Take Phosphate Binders : The Role of Dialysis Patients' Medication Beliefs
Wileman, Vari; Chilcot, Joseph; Norton, Sam; Hughes, Lyndsay; Wellsted, D.; Farrington, Ken (2011)Objective: Patients with end-stage renal disease (ESRD) receiving haemodialysis are at risk of cardiovascular disease and bone disorders related to high levels of serum phosphate (PO(4)). Phosphate binders are an important ... -
Colorectal tumor vascularity: quantitative assessment with multidetector CT--do tumor perfusion measurements reflect angiogenesis?
Goh, Vicky; Halligan, Steve; Daley, Frances; Wellsted, D.; Guenther, Thomas; Bartram, Clive I (2008)To establish the relationships between quantitative perfusion computed tomography (CT) parameters-specifically, primary tumor blood flow, blood volume, transit time, and permeability surface-area product-and immunohistologic ... -
Colorectal Tumor Vascularity: Quantitative Assessment with Multidetector CT—Do Tumor Perfusion Measurements
Goh, V.; Halligan, S.; Daley, F.; Wellsted, D.; Guenther, T.; Bartram, C.I. (2008) -
Commercial software upgrades may significantly alter Perfusion CT parameter values in colorectal cancer
Goh, V.; Shastry, M.; Engledow, A.; Reston, J.; Peck, J.; Endozo, R.; Rodriguez-Justo, M.; Taylor, S.A.; Halligan, S. (2010)Objective : To determine how commercial software platform upgrades impact on derived parameters for colorectal cancer. Materials and methods Following ethical approval, 30 patients with suspected colorectal cancer underwent ... -
Conducting randomized trials in general practice : methodological and practical issues
Ward, E.; King, M.; Lloyd, M.; Bower, P.; Friedli, K. (1999-11)The evaluation of the outcome of health services technologies is a requirement for their efficient provision in clinical practice. The most reliable evidence for treatment efficacy comes from randomized trials. Randomized ... -
Counselling and community psychiatric nurses
Friedli, Karen; King, M. (1995) -
Counselling and Psychotherapy for the Prevention of Suicide : a Systematic Review of the Evidence
Winter, David; Bradshaw, Siobhan; Bunn, Frances; Wellsted, D. (British Association for Counselling and Psychotherapy, 2009) -
Dementia Education and Training in Hertfordshire and Bedfordshire : An organisational audit commissioned by Health Education England
Mayrhofer, Andrea; Goodman, Claire; Sharpe, Rachel; Dye, Helen (University of Hertfordshire, 2014-12-16)This audit established the range of dementia education available to NHS staff, social care staff and GPs across the two counties. It reports on current uptake of training, course content, assessment and accreditation of ... -
Depression in End-Stage Renal Disease : Current Advances and Research
Chilcot, J.; Wellsted, D.; Farrington, Ken (2010)Depression or the presence of significant depressive symptoms remains common in patients with end-stage renal disease (ESRD). It is thought that 20–30% of ESRD patients have significant depressive symptoms, although there ... -
Depression on dialysis
Chilcot, J.; Wellsted, D.; Da Silva Gane, M.; Farrington, Ken (2008)Depression is the most common psychopathological condition among patients with end-stage renal disease (ESRD), yet it is still under-recognized and misdiagnosed. Depression reduces quality of life and has a negative clinical ... -
Depression Symptoms in Haemodialysis Patients Predict All-Cause Mortality but Not Kidney Transplantation : A Cause-Specific Outcome Analysis
Chilcot, Joseph; Guirguis, Ayman; Friedli, Karin; Almond, Michael K; Day, Clara; Da Silva Gane, Maria; Davenport, Andrew; Fineberg, Naomi A.; Spencer, Benjamin; Wellsted, David; Farrington, Ken (2017-07-31)Background: Depression is common in haemodialysis (HD) patients and associated with poor outcomes. Purpose: To evaluate whether depression symptoms predict survival and transplantation in a large sample of haemodialysis ... -
Developing key working
Mengoni, Silvana; Oates, John; Bardsley, Janet (Council for Disabled Children, 2014)The aim of this ‘Developing Key Working’ Guide is to offer guidance to those involved in developing, managing and delivering key working. The primary audience is commissioners and managers in local areas and in the private, ...