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Browsing by Author "Guirguis, Amira"
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Ethnic disparities in the uptake of pharmacy services
Bancroft, Stephanie; Heading, Christine; Guirguis, Amira; Shah, Shreya; Shah, Usha; Attar-Zadeh, Darush (2016-09-24)This is a letter to the editor of The Pharmaceutical Journal regarding results of an audit undertaken over London North West London. Results of the audit showed racial disparities in the uptake of pharmacy services. This ... -
Exploration of the use of new psychoactive substances by individuals in treatment for substance misuse in the UK.
Gittins, Rosalind; Guirguis, Amira; Schifano, Fabrizio; Maidment, Ian (2018-03-30)Substance misuse services need to meet the growing demand and needs of individuals using new psychoactive substances (NPS). A review of the literature identified a paucity of research regarding NPS use by these individuals ... -
Exploring the Association Between Suicidal Thoughts, Self-Injury, and GLP-1 Receptor Agonists in Weight Loss Treatments: Insights from Pharmacovigilance Measures and Unmasking Analysis
Guirguis, Amira; Chiappini, Stephania; Papanti, P G Duccio; Vickers-Smith, Rachel; Harris, Daniel; Corkery, John; Arillotta, Davide; Floresta, Giuseppe; Martinotti, Giovanni; Schifano, Fabrizio (2024-05)Introduction: The study addresses concerns about potential psychiatric side effects of Glucagon-like peptide-1 receptor agonists (GLP-1 RA). Aim: The aim of this work was to analyse adverse drug reports (ADRs) from the ... -
Exploring the baseline knowledge and experience of healthcare professionals in the United Kingdom on Novel Psychoactive Substances
Guirguis, Amira; Smeeton, Nigel; Zaman, Hadar; Felice, Anne-Marie; Bancroft, Stephanie; Gittins, Rosalind; Hawksworth, Gill; Corkery, John; Schifano, Fabrizio (2020-03-02)Objective: This survey aimed to explore knowledge and experience on novel psychoactive substances (NPS) of healthcare professionals (HCPs). The study also aimed to assess how HCPs would like to improve their knowledge of ... -
Exploring the Nexus of Binge Eating Disorder (BED), New Psychoactive Substances (NPS), and Misuse of Pharmaceuticals: Charting a Path Forward
Chiappini, Stefania; Papanti Pelletier, G. Duccio; Vickers-Smith, Rachel; Corkery, John; Guirguis, Amira; Martinotti, Giovanni; Schifano, Fabrizio (2023-10-31) -
A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases
Chiappini, Stefania; Vickers-Smith, Rachel; Guirguis, Amira; Corkery, John Martin; Martinotti, Giovanni; Schifano, Fabrizio (2022-05-01)Despite increasing reports, antidepressant (AD) misuse and dependence remain underestimated issues, possibly due to limited epidemiological and pharmacovigilance evidence. Thus, here we aimed to determine available ... -
Focus on clozapine withdrawal- and misuse-related cases, as reported to the European Medicines Agency (EMA) pharmacovigilance database
Chiappini, Stephania; Schifano, Fabrizio; Corkery, John Martin; Guirguis, Amira (2020-02-16)Background: Clozapine is of high clinical relevance for the management of both treatment-resistant schizophrenia and psychotic disturbances with concurrent drug misuse. Although the molecule presents with a range of ... -
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ... -
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ... -
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ... -
GLP-1 Receptor Agonists and Related Mental Health Issues; Insights from a Range of Social Media Platforms Using a Mixed-Methods Approach
Arillotta, Davide; Floresta, Giuseppe; Guirguis, Amira; Corkery, John Martin; Catalani, Valeria; Martinotti, Giovanni; Sensi, Stefano L.; Schifano, Fabrizio (2023-10-24)The emergence of glucagon-like peptide-1 receptor agonists (GLP-1 RAs; semaglutide and others) now promises effective, non-invasive treatment of obesity for individuals with and without diabetes. Social media platforms’ ... -
Handheld Raman Spectroscopy in the First UK Home Office Licensed Pharmacist-Led Community Drug Checking Service
Mullin, Anthony; Scott, Mark; Vaccaro, Giorgia; Gittins, Rosalind; Ferla, Salvatore; Schifano, Fabrizio; Guirguis, Amira (2023-03-08)Across the world, the interest in point-of-care drug checking as a harm-reduction intervention is growing. This is an attempt to improve intelligence about current drug trends and reduce drug-related morbidity and mortality. ... -
Identification and Classification of New Psychoactive Substances Using Raman Spectroscopy and Chemometrics
Guirguis, Amira (2017-06-14)The sheer number, continuous emergence, heterogeneity and wide chemical and structural diversity of New Psychoactive Substance (NPS) products are factors being exploited by illicit drug designers to obscure detection of ... -
Identification of new psychoactive substances (NPS) using handheld Raman Spectroscopy employing both 785 and 1064 nm laser sources
Guirguis, Amira; Girotto, Sarah; Berti, Benedetta; Stair, Jacqueline (2017-04-01)The chemical identification of new psychoactive substances (NPS) in the field is challenging due not only to the plethora of substances available, but also as a result of the chemical complexity of products and the chemical ... -
Identification of new psychoactive substances using Raman spectroscopy: handheld and computational approaches.
Guirguis, Amira; Kirton, Stewart; Zloh, Mire; Samaras, Eleftherios; Girotto, Sarah; Berti, Benedetta; Stair, Jacqueline (Research and Advances in Psychiatry, 2016-05)At this conference, I gave a presentation on the identification of new psychoactive substances using handheld Raman spectroscopy and chemometrics. -
Identifying new/emerging psychoactive substances at the time of COVID-19; a web-based approach
Catalini, Valeria; Arillotta, Davide; Corkery, John Martin; Guirguis, Amira; Vento, Alessandro; Schifano, Fabrizio (2021-02-09)COVID-19-related disruptions of people and goods' circulation can affect drug markets, especially for new psychoactive substances (NPSs). Drug shortages could cause a change in available NPS, with the introduction of new, ... -
In silico studies on recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines
Catalani, Valeria; Floresta, Giuseppe; Botha, Michelle; Corkery, John Martin; Guirguis, Amira; Vento, Alessandro; Abbate, Vincenzo; Schifano, Fabrizio (2022-07-15)Currently, increasing availability and popularity of designer benzodiazepines (DBZDs) constitutes a primary threat to public health. To assess this threat, the biological activity/potency of DBZDs was investigated using ... -
An Insight into Z-Drug Abuse and Dependence : An Examination of Reports to the European Medicines Agency Database of Suspected Adverse Drug Reactions
Schifano, Fabrizio; Chiappini, Stefania; Corkery, John Martin; Guirguis, Amira (2019-04-01)BACKGROUND: Although originally marketed as safe alternatives to the habit-forming benzodiazepines, growing numbers of zaleplon, zolpidem, and zopiclone ("Z-drugs") clinical concerns relating to their potential of abuse, ... -
Intended and Unintended Use of Cathinone Mixtures
Guirguis, Amira; Corkery, John; Stair, Jacqueline; Kirton, Stewart; Zloh, Mire; Schifano, Fabrizio (2017-06-28)Introduction: Cathinones are one of the most popular categories of new psychoactive substances (NPS) consumed. Cathinones have different pharmacological activities and receptor selectivity for monoamine transporters based ... -
An investigation into the relationship(s) between the different chemical classes of synthetic cathinones and their effects: desired, adverse and toxic
Corkery, John; Guirguis, Amira; Orsolini, Laura; Papanti, Duccio; Schifano, Fabrizio (2017-10-24)