Browsing by Author "Chiappini, Stephania"

Now showing items 1-20 of 25

    • Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems 

      Schifano, Fabrizio; Chiappini, Stephania; Corkery, John; Guirguis, Amira (2019-02-01)
      Objective: A recent, global, increase in the use of opioids including the prescribing, highly potent, fentanyl has been recorded. Due its current popularity and the potential lethal consequences of its intake, we aimed ...

    • The benzydamine experience: A systematic review of Benzydamine abuse 

      Chiappini, Stephania; Miuli, Andrea; Mosca, Alessio; Pettorruso, Mauro; Guirguis, Amira; Corkery, John Martin; Martinotti, Giovanni; di Giannantonio, Massimo; Schifano, Fabrizio (2021-01-13)
      Background: Both prescription and over-the-counter (OTC) drugs recently emerged among novel psychoactive substances (NPS) being reported as ingested for recreational purposes. Among them, benzydamine (BZY), normally ...

    • The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective 

      Orsolini, Laura; Chiappini, Stephania; Papanti, Duccio; De Berardis, Domenico; Corkery, John Martin; Schifano, Fabrizio (2019-11-20)
      The critical spread and dissemination of novel psychoactive substances (NPS), particularly among the most vulnerable youngsters, may pose a further concern about the psychotic trajectories related to the intake of new ...

    • Deaths of individuals aged 16-24 years in the UK after using mephedrone 

      Loi, Barbara; Corkery, John; Claridge, Hugh; Goodair, Christine; Chiappini, Stephania; Gimeno Clemente, Carla; Schifano, Fabrizio (2015-07-28)
      Objective: Mephedrone is a stimulant drug chemically related to amphetamine, with effects similar to those of amphetamine and cocaine. This study aims to analyse fatalities following ingestion of mephedrone in the UK amongst ...

    • The e-psychonaut drugs’ psychopharmacology 

      Schifano, Fabrizio; Chiappini, Stephania; Corkery, John Martin; Scherbaum, Norbert; Guirguis, Amira (2021-04-01)
      The focus here was on the pharmacological and clinical pharmacological issues pertaining to the vast range of drugs (e.g. synthetic cannabimimetics, synthetic opioids, novel stimulants, novel psychedelics, PCP/ketamine-like ...

    • Editorial: Prescribing Psychotropics: Misuse, Abuse, Dependence, Withdrawal and Addiction-Volume II 

      Chiappini, Stephania; Schifano, Fabrizio; Martinotti, Giovanni (2022-10-18)

    • Exploring the Association Between Suicidal Thoughts, Self-Injury, and GLP-1 Receptor Agonists in Weight Loss Treatments: Insights from Pharmacovigilance Measures and Unmasking Analysis 

      Guirguis, Amira; Chiappini, Stephania; Papanti, P G Duccio; Vickers-Smith, Rachel; Harris, Daniel; Corkery, John; Arillotta, Davide; Floresta, Giuseppe; Martinotti, Giovanni; Schifano, Fabrizio (2024-05)
      Introduction: The study addresses concerns about potential psychiatric side effects of Glucagon-like peptide-1 receptor agonists (GLP-1 RA). Aim: The aim of this work was to analyse adverse drug reports (ADRs) from the ...

    • Fatalities Associated with Mephedrone in Combination with Other Stimulant Drugs in Young People Aged 16-24 Years 

      Loi, Barbara; Chiappini, Stephania; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Schifano, Fabrizio (2013-12)
      Introduction: Mephedrone is a stimulant Class B drug chemically related to amphetamine. It comes in tablet or powder form and has no therapeutic use. Mephedrone’s reported effects are similar to those of amphetamine and ...

    • Focus on clozapine withdrawal- and misuse-related cases, as reported to the European Medicines Agency (EMA) pharmacovigilance database 

      Chiappini, Stephania; Schifano, Fabrizio; Corkery, John Martin; Guirguis, Amira (2020-02-16)
      Background: Clozapine is of high clinical relevance for the management of both treatment-resistant schizophrenia and psychotic disturbances with concurrent drug misuse. Although the molecule presents with a range of ...

    • Is there a potential of misuse for venlafaxine and bupropion? 

      Schifano, Fabrizio; Chiappini, Stephania (2018-03-21)
      Objective: Traditionally, studies on the nonmedical use of pharmaceutical products have focused on controlled substances; e.g. opiates/opioids; and benzodiazepines. Although both bupropion and venlafaxine have been reported ...

    • Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population 

      Chiappini, Stephania; Ceci, Franca; Mosca, Alessio; Di Carlo, Francesco; Burkauskas, Julius; Pettorruso, Mauro; Martinotti, Giovanni; Guirguis, Amira; Corkery, John Martin; Scherbaum, Norbert; Schifano, Fabrizio; di Giannantonio, Massimo (2022-10-06)
      Background: During the past decade, the misuse of over-the-counter (OTC) medicines has become a global public health concern, especially among young people. In this study, we aimed to explore the OTC consumption and related ...

    • Methoxetamine-related deaths in the UK : an overview 

      Chiappini, Stephania; Claridge, Hugh; Corkery, John; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2015-07-28)
      Objective: The goal of this study is to provide an update on the data given on methoxetamine (MXE)-related fatalities that occurred in 2011–2013, presented at the Second International Conference on Novel Psychoactive ...

    • Methoxetamine: An Analogue of Ketamine 

      Chiappini, Stephania; Claridge, Hugh; Corkery, John; Gimeno Clemente, Carla; Goodair, Christine; Loi, Barbara; Schifano, Fabrizio (2013-12)
      Introduction: Methoxetamine acts similarly to a non-competitive antagonist at the N-methyl-aspartate receptor and a Dopamine reuptake inhibitor. Its behavioural effects resemble those induced by dissociative anesthetics, ...

    • New Psychoactive Substances (NPS) and Serotonin Syndrome onset: a Systematic Review 

      Schifano, Fabrizio; Chiappini, Stephania; Corkery, John; Scherbaum, Norbert; Napoletano, Flavia; Arillotta, Davide; Catalani, Valeria; Vento, Alessandro; Pettorruso, Mauro; Martinotti, Giovanni; di Giannantonio, Massimo; Guirguis, Amira (2021-05-01)
      The use of several new psychoactive substances (NPS) has become very popular and is posing global health risks. Chemically and pharmacologically diverse molecules are constantly emerging and are presenting with a wide range ...

    • New psychoactive substances (NPS), psychedelic experiences, and dissociation: clinical and clinical pharmacological issues 

      Schifano, Fabrizio; Napoletano, Flavia; Chiappini, Stephania; Orsolini, Laura; Guirguis, Amira; Corkery, John Martin; Bonaccorso, Stefania; Ricciardi, Angelo; Scherbaum, Norbert; vento, alessandro (2019-04-23)
      Purpose of the review: A significant increase in the number, type, and availability of new psychoactive substances (NPS) with dissociative and psychedelic potential has occurred worldwide over the last few decades. Psychedelic ...

    • 'New/Designer Benzodiazepines': an analysis of the literature and psychonauts’ trip reports 

      Orsolini, Laura; Corkery, John; Chiappini, Stephania; Guirguis, Amira; Vento, Alessandro; De Berardis, Domenico; Papanti, Duccio; Schifano, Fabrizio (2020-01-10)
      Background: NPS belonging to the benzodiazepine (BZD) class, e.g., ‘legal/designer BZDs’/‘research chemicals’, have recently emerged in the drug (mainly online/virtual) market. Objective: While certain NPS belonging to the ...

    • New/emerging psychoactive substances and associated psychopathological consequences 

      Schifano, Fabrizio; Napoletano, Flavia; Chiappini, Stephania; Guirguis, Amira; Corkery, John; Bonaccorso, Stefania; Ricciardi, Angelo; Scherbaum, Norbert; vento, alessandro (2019-07-22)
      BackgroundThe present paper provides an updated review of both the large number of new/novel/emerging psychoactive substances (NPS) and their associated psychopathological consequences. Focus was here given on identification ...

    • Opioid painkillers' dependence in a sample of elderly medical inpatients 

      Chiappini, Stephania; Schifano, Fabrizio; Martinotti, Giovanni; Strasser, Johanna; Bonnet, Udo; Scherbaum, Norbert (2021-02-16)
      BACKGROUND: Over the past few years there has been a growing concern towards prescription opioid misuse/dependence in the elderly. Thus, our study aimed at investigating the prevalence of previous and current prescribing ...

    • Pregabalin: a range of misuse-related unanswered questions 

      Schifano, Fabrizio; Chiappini, Stephania (2019-05-01)

    • Prescribing Psychotropics: Misuse, Abuse, Dependence, Withdrawal and Addiction 

      Schifano, Fabrizio; Martinotti, Giovanni; Chiappini, Stephania; Department of Clinical, Pharmaceutical and Biological Science; Centre for Health Services and Clinical Research; Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Unit; School of Life and Medical Sciences (Frontiers Media S.A., 2021-06-21)
      Recently, the growing use of prescription drugs for recreational purposes has been reported widely in the literature. However, the true extent and nature of such use is not completely understood. Some medications are already ...