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Browsing by Author "Corkery, John Martin"
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Alprazolam-related deaths in Scotland, 2004-2020
Corkery, John Martin; Guirguis, Amira; Chiappini, Stefania; Martinotti, Giovanni; Schifano, Fabrizio (2022-09-27)Background: The benzodiazepine drug alprazolam, a fast-acting tranquiliser, cannot be prescribed on the National Health Service in the United Kingdom. Illicit alprazolam supply and consumption have increased. Concern about ... -
The benzydamine experience: A systematic review of Benzydamine abuse
Chiappini, Stephania; Miuli, Andrea; Mosca, Alessio; Pettorruso, Mauro; Guirguis, Amira; Corkery, John Martin; Martinotti, Giovanni; di Giannantonio, Massimo; Schifano, Fabrizio (2021-01-13)Background: Both prescription and over-the-counter (OTC) drugs recently emerged among novel psychoactive substances (NPS) being reported as ingested for recreational purposes. Among them, benzydamine (BZY), normally ... -
Beyond the Purple Drank. Study of promethazine abuse according to the European Medicines Agency (EMA) Adverse Drug Reactions (ADR) reports.
Chiappini, Stefania; Schifano, Fabrizio; Corkery, John Martin; Guirguis, Amira (2021-01-10)Background: Promethazine is a medicinal product, available on its own or in combination with other ingredients including dextromethorphan, paracetamol, and/or expectorants. Anecdotal reports have however indicated that ... -
The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective
Orsolini, Laura; Chiappini, Stephania; Papanti, Duccio; De Berardis, Domenico; Corkery, John Martin; Schifano, Fabrizio (2019-11-20)The critical spread and dissemination of novel psychoactive substances (NPS), particularly among the most vulnerable youngsters, may pose a further concern about the psychotic trajectories related to the intake of new ... -
Covid-19 pandemic impact on substance misuse: a social media listening, mixed method analysis.
Arillotta, Davide; Guirguis, Amira; Corkery, John Martin; Scherbaum, Norbert; Schifano, Fabrizio (2021-07-09)The restrictive measures adopted during the COVID-19 pandemic modified some previously consolidated drug use patterns. A focus on social networks allowed drug users to discuss, share opinions and provide advice during a ... -
Descriptive research into large-scale user data from an established alcohol identification and brief advice (IBA) intervention website
Kerr, Dylan Andrew; Corkery, John Martin (figshare, 2024-01-16)Alcohol misuse causes significant health harms, including early mortality, increased healthcare and wider governmental costs. Identification and Brief Advice (IBA) interventions can reduce alcohol consumption, prevent ... -
Designer Benzodiazepines’ Activity on Opioid Receptors: A Docking Study
Catalani, Valeria; Botha, Michelle; Corkery, John Martin; Guirguis, Amira; Vento, Alessandro; Schifano, Fabrizio (2022-09-22)BACKGROUND: Previous studies have reported that benzodiazepines (BZDs) seem to enhance euphoric and reinforcing properties of opioids in opioid users so that a direct effect on opioid receptors has been postulated, together ... -
The e-psychonaut drugs’ psychopharmacology
Schifano, Fabrizio; Chiappini, Stephania; Corkery, John Martin; Scherbaum, Norbert; Guirguis, Amira (2021-04-01)The focus here was on the pharmacological and clinical pharmacological issues pertaining to the vast range of drugs (e.g. synthetic cannabimimetics, synthetic opioids, novel stimulants, novel psychedelics, PCP/ketamine-like ... -
The e-psychonauts’ ‘Spiced’ World; assessment of the synthetic cannabinoids’ information available online
Zangani, Caroline; Schifano, Fabrizio; Napoletano, Flavia; Arillotta, Davide; Gilgar, Liam; Guirguis, Amira; Corkery, John Martin; Gambini, Orsola; Vento, Alessandro (2020-03-02)Background: A wide range of novel psychoactive substances (NPS) is regularly searched and discussed online by web-based drug enthusiasts (i.e. the e-psychonauts). Among NPS, the range of synthetic cannabinoids (SC; ‘Spice’) ... -
Exploring the Potential Impact of GLP-1 Receptor Agonists on Substance Use, Compulsive Behavior, and Libido: Insights from Social Media Using a Mixed-Methods Approach
Arillotta, Davide; Floresta, Giuseppe; Papanti Pelletier, G. Duccio; Guirguis, Amira; Corkery, John Martin; Martinotti, Giovanni; Schifano, Fabrizio (2024-06-20)Glucagon-like peptide-1 (GLP-1) is involved in a range of central and peripheral pathways related to appetitive behavior. Hence, this study explored the effects of glucagon-like peptide-1 receptor ag-onists (GLP-1 RAs) on ... -
First death involving 4-Fluoroethylphenidate (4F-EPH): case-report, user experiences, and review of the related literature
Corkery, John Martin; Schifano, Fabrizio (2022-12-01)Background: 4-Fluoroethylphenidate (4F-EPH) is a psychoactive substance, sold primarily over the Internet as a ‘research chemical’. Recreational and ‘functional’ use of this drug has been reported by online user fora. ... -
A Focus on Abuse/Misuse and Withdrawal Issues with Selective Serotonin Reuptake Inhibitors (SSRIs): Analysis of Both the European EMA and the US FAERS Pharmacovigilance Databases
Chiappini, Stefania; Vickers-Smith, Rachel; Guirguis, Amira; Corkery, John Martin; Martinotti, Giovanni; Schifano, Fabrizio (2022-05-01)Despite increasing reports, antidepressant (AD) misuse and dependence remain underestimated issues, possibly due to limited epidemiological and pharmacovigilance evidence. Thus, here we aimed to determine available ... -
Focus on clozapine withdrawal- and misuse-related cases, as reported to the European Medicines Agency (EMA) pharmacovigilance database
Chiappini, Stephania; Schifano, Fabrizio; Corkery, John Martin; Guirguis, Amira (2020-02-16)Background: Clozapine is of high clinical relevance for the management of both treatment-resistant schizophrenia and psychotic disturbances with concurrent drug misuse. Although the molecule presents with a range of ... -
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ... -
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ... -
Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants
Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ... -
GLP-1 Receptor Agonists and Related Mental Health Issues; Insights from a Range of Social Media Platforms Using a Mixed-Methods Approach
Arillotta, Davide; Floresta, Giuseppe; Guirguis, Amira; Corkery, John Martin; Catalani, Valeria; Martinotti, Giovanni; Sensi, Stefano L.; Schifano, Fabrizio (2023-10-24)The emergence of glucagon-like peptide-1 receptor agonists (GLP-1 RAs; semaglutide and others) now promises effective, non-invasive treatment of obesity for individuals with and without diabetes. Social media platforms’ ... -
Hearing Impairment in Children Living with HIV in Haiti
Valeriani, Vienna; Patro, Ankita; Segaren, Nathaniel; Michel, Daphnee; Canez, Anaelle; Lamour, Shaina; Gilles, Patrick J.; Charles, Sophia; Corkery, John Martin; Netterville, James L.; Jayawardena, Asitha D.L. (2022-11-30)Objective To identify the prevalence of hearing impairment and associated risk factors in children living with human immunodeficiency virus (HIV) in Haiti. Methods A validated smartphone-based platform with pure-tone ... -
Ibogaine as a treatment for substance misuse : Potential benefits and practical dangers
Corkery, John Martin (Elsevier, 2018-01-01)Ibogaine is an indole alkaloid found in the root bark of the Iboga shrub native to west Africa possessing hallucinogenic properties. For centuries it has been used in religious ceremonies and to gain spiritual enlightenment. ... -
Identifying new/emerging psychoactive substances at the time of COVID-19; a web-based approach
Catalini, Valeria; Arillotta, Davide; Corkery, John Martin; Guirguis, Amira; Vento, Alessandro; Schifano, Fabrizio (2021-02-09)COVID-19-related disruptions of people and goods' circulation can affect drug markets, especially for new psychoactive substances (NPSs). Drug shortages could cause a change in available NPS, with the introduction of new, ...