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Browsing by Author "Drakulić, B.J."
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Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains : Structural insights based on similarity and molecular interaction fields
Drakulić, B.J.; Stavri, M.; Gibbons, S.; Žižak, Ž.S.; Verbić, T.Ž.; Juranić, I.O.; Zloh, Mire (2009-12-07)(Chemical Equation Presented) Similar structure=similar activity? The effect of substituents on the antibacterial activity of aryldiketo acids has been rationalised by molecular interaction fields and similarity studies ... -
The effect of phenyl substituents on C NMR shifts and metal ions binding to 4-Phenyl-2,4-dioxobutanoic acid derivatives
Verbić, T.Z.; Juranić, I.O.; Drakulić, B.J.; Zloh, Mire (2009-12-01)Butanoic moiety of 4-aryl-2,4-dioxobutanoic acids is involved in interactions with metal ions within HIV-1 integrase active site. Sixteen congeneric 4-phenyl-2,4-dioxobutanoic acid derivatives with different substitution ... -
An LFER study of the protolytic equilibria of 4-aryl-2,4-dioxobutanoic acids in aqueous solutions
Verbić, T.Ž.; Pecelj, J.R.; Juranić, I.O.; Drakulić, B.J.; Zloh, Mire; Popović, G.V. (2007)The protolytic equilibria of 13 4-aryl-2,4-dioxobutanoic acids (ADKs) were spectrophotometrically studied in aqueous solutions in the pH range 1-9 at 25±1°C and an ionic strength of 0.1 mol l (NaCl), with the exception of ... -
Role of complexes formation between drugs and penetration enhancers in transdermal delivery
Drakulić, B.J.; Juranić, I.O.; Erić, S.; Zloh, Mire (2008-11-03)The use of chemical penetration enhancers (CPE) is growing due to their ability to improve drug delivery through the skin. A possible mechanism of penetration enhancement could involve the complex formation between drug ...