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Browsing by Author "Holcombe, James A."
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Immobilized peptides/amino acids on solid supports for metal remediation
Malachowski, L.; Stair, Jacqueline; Holcombe, James A. (2004-04)Recently, a significant amount of work has focused on metal binding by natural systems for various applications. This review will focus on the utility of amino acids, short peptides, and proteins that have been immobilized ... -
Metal binding characterization and conformational studies using Raman microscopy of resin-bound poly(aspartic acid)
Stair, Jacqueline L.; Holcombe, James A. (2007-03-01)The metal binding capacities, conditional stability constants, and secondary structure of immobilized polyaspartic acid (PLAsp) (n = 6, 20, and 30) on TentaGel resin were determined when binding Mg2+, Co2+, Cd2+, and Ni2+. ... -
Metal remediation and preconcentration using immobilized short-chain peptides composed of aspartic acid and cysteine
Holcombe, James A.; Stair, Jacqueline (2005-08)Short-chain peptides (two and seven residues) consisting of a glycine (Gly) attachment group and various combinations of cysteine (Cys) and/or aspartic acid (Asp) were synthesized by Fmoc solid phase peptide synthesis ... -
Quantitative determination of single-bead metal content from a peptide combinatorial library
Stair, Jacqueline L.; White, Brianna R.; Rowland, Adam; Holcombe, James A. (2006-11-13)An electrothermal vaporizer inductively coupled plasma mass spectrometer (ETV-ICPMS) was used to quantitatively screen metals bound to single polystyrene (TentaGel) beads with immobilized oligopeptides. Tests were performed ...