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Browsing by Author "Hudson, A.L."
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[3H]2-(2-Benzofuranyl)-2-imidazoline : a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors
Lione, Lisa; Nutt, D.J.; Hudson, A.L. (1996-05)This is the first study characterising the binding of the new imidazoline I2 receptor selective radioligand [3H]2-(2-benzofuranyl)-2-imidazoline (2-BFI) to rabbit brain membranes. [3H]2-BFI binding was found to be saturable ... -
Characterisation and localisation of [3H]2-(2-benzofuranyl)-2-imidazoline binding in rat brain : a selective ligand for imidazoline I2 receptors
Lione, Lisa; Nutt, D.J.; Hudson, A.L. (1998-07) -
Characterization of imidazoline receptors by radioligand binding
Hudson, A.L.; Lione, Lisa (Humana Press, 1999) -
Noradrenergic mechanisms in the prefrontal cortex.
Nutt, D.J.; Lalies, M.D.; Lione, Lisa; Hudson, A.L. (1997)There is growing evidence that noradrenergic inputs to the prefrontal cortex (PFC) play an important role in regulating its function. This paper reviews the pharmacological control of noradrenaline (NA) release in this ... -
Novel selective compounds for the investigation of imidazoline receptors
Hudson, A.L.; Gough, R.; Tyacke, Robin; Lione, Lisa; Lalies, M.D.; Lewis, J.; Husbands, S.; Knight, P.; Murray, F.; Hutson, P.; Nutt, D.J. (1999-06)Over several years our group has sought to synthesize and identify selective ligands for imidazoline (I) receptors, in particular the I2 binding site. As a consequence, [3H]2-(2-benzofuranyl)-2-imidazoline (2BFI) has proved ...