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Browsing by Author "Jones, D.G."
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Dexamethasone decreases plasma levels of the prochiral fenbendazole and its chiral and achiral metabolites in sheep
Sanchez, S.; Small, J.; Jones, D.G.; McKellar, Quintin (2003-07)1. The effect of co-administration of either short- or long-acting formulations of DXM on hepatic function and the plasma pharmacokinetic behaviour of prochiral fenbendazole (FBZ) and its metabolites was evaluated in sheep. ... -
Pharmacokinetic/pharmacodynamic relationships of antimicrobial drugs used in veterinary medicine
McKellar, Quintin; Sanchez Bruni, S.F.; Jones, D.G. (2004-12)The rise in incidence of antimicrobial resistance, consumer demands and improved understanding of antimicrobial action has encouraged international agencies to review the use of antimicrobial drugs. More detailed understanding ... -
Plasma achiral and chiral pharmacokinetic behaviour of intravenous oxfendazole co-administered with piperonyl butoxide in sheep
Sanchez, S.; Jones, D.G.; Small, J.; McKellar, Quintin (2002-02)Co-administration of piperonyl butoxide (PB) potentiates fenbendazole (FBZ) in small ruminants. The resultant increase in bioavailability of FBZ and its metabolite oxfendazole (OFZ) has important implications for the ...