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Browsing by Author "Jones, S.A."
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Discriminating the molecular identity and function of discrete supramolecular structures in topical pharmaceutical formulations
Benaouda, F.; Brown, Marc; Ganguly, S.; Jones, S.A.; Martin, G.P. (2012-09-04)There is a need to understand how solvent structuring influences drug presentation in pharmaceutical preparations, and the aim of this study was to characterize the properties of propylene glycol (PG)/water supramolecular ... -
Dynamic foams in topical drug delivery
Zhao, Y.; Jones, S.A.; Brown, Marc (2010)Objectives: Pharmaceutical foams are not new inventions and their application in topical therapy can be traced back three decades. However, foam formulations have been gaining in popularity with over 100 patents published ... -
The effect of disulphide bond disruption on the barrier integrity of the human nail
Baraldi, A.; Khengar, R.H.; Murdan, S.; Traynor, M.J.; Jones, S.A.; Brown, Marc (Royal Society of Chemistry, 2014-04-14)Onychomycosis is the fungal infection of the nail and accounts for approximately 50% of all nail disorders [1]. The prevalence of onychomycosis is increasing and currently up to 10 % of people in the UK and US are reported ... -
Topical corticosteroid delivery into human skin using hydrofluoroalkane metered dose aerosol sprays
Reid, M.L.; Benaouda, F.; Khengar, Rajeshree H.; Jones, S.A.; Brown, Marc (2013-08-16)Drug loaded hydrofluoroalkane (HFA) sprays can generate effective pharmaceutical formulations, but a deeper understanding of the manner in which these dynamic systems drive the process of in situ semi-solid dosage form ... -
Understanding heat facilitated drug transport across human epidermis
Wood, D.G.; Brown, Marc; Jones, S.A. (2012-08-01)The application of moderate heat is a safe and effective means to increase drug transport across human skin. However, the cascade of events that follows the exposure of a topical skin formulation to a heating source is not ...