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Browsing by Author "Kopsch, Thomas"
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Development of an adaptive bypass element for passive entrainment flow control in dry powder inhalers
Kopsch, Thomas; Murnane, Darragh; Symons, Digby (2019-08-01)The release of drug from dry powder inhalers is strongly dependent on the patient's inhalation profile. To maximise the effect of the treatment, it is necessary to optimise dry powder inhalers to achieve drug delivery that ... -
Optimizing the Entrainment Geometry of a Dry Powder Inhaler : Methodology and Preliminary Results
Kopsch, Thomas; Murnane, Darragh; Symons, Digby (2016-11-01)Purpose: For passive dry powder inhalers (DPIs) entrainment and emission of the aerosolized drug dose depends strongly on device geometry and the patient’s inhalation manoeuvre. We propose a computational method for ... -
A personalized medicine approach to the design of dry powder inhalers: : Selecting the optimal amount of bypass
Kopsch, Thomas; Murnane, Darragh; Symons, Digby (2017-08-30)In dry powder inhalers (DPIs) the patient's inhalation manoeuvre strongly influences the release of drug. Drug release from a DPI may also be influenced by the size of any air bypass incorporated in the device. If the ...