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Browsing by Author "Lip, Gregory Y H"
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Antithrombotic in atrial fibrillation and coronary artery disease – Does less mean more?
Gue, Ying X.; Gorog, Diana; Lip, Gregory Y H (2022-06-15)In the treatment of patients with chronic coronary syndrome, the use of antiplatelets in the form of aspirin is a class 1 indication in the prevention of future thrombotic events.1 Similarly, oral anticoagulation (OAC) has ... -
Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation
Spinthakis, Nikolaos; Gue, Ying X.; Farag, Mohamed; Srinivasan, Manivannan; Wellsted, David; Lip, Gregory Y H; Arachchillage, Deepa RJ; Gorog, Diana (2019-09-01)AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which strongly relates to improved functional outcome. The impact of oral anticoagulants ... -
Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: An European and Asia-Pacific Expert Consensus Paper
Gorog, Diana; Gue, Ying X.; Chao, Tze-Fan; Fauchier, Laurent; Ferreiro, Jose Luis; Huber, Kurt; Konstantinidis, Stavros V; Lane, Deirdre A; Marin, Francisco; Oldgren, Jonas; Potpara, Tatjana; Roldan, Vanessa; Rubboli, Andrea; Sibbing, Dirk; Tse, Hung-Fat; Vilahur, Gemma; Lip, Gregory Y H (2022-03-22)Whilst there is a clear clinical benefit of oral anticoagulation (OAC) in patients with atrial fibrillation (AF) and venous thromboembolism (VTE) in reducing the risks of thromboembolism, major bleeding events (especially ... -
Assessment of endogenous fibrinolysis in clinical using novel tests - Ready for clinical roll-out?
Gue, Ying X.; Ding, Wern Yew; Lip, Gregory Y H; Gorog, Diana (2021-04-01)The occurrence of thrombotic complications, which can result in excess mortality and morbidity, represent an imbalance between the pro-thrombotic and fibrinolytic equilibrium.The mainstay treatment of these complications ... -
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis.
Gorog, Diana; Ferreiro, Jose Luis; Ahrens, Ingo; Ako, Junya; Geisler, Tobias; Halvorsen, Sigrun; Huber, Kurt; Jeong, Young-Hoon; Navarese, Eliano P; Rubboli, Andrea; Sibbing, Dirk; Siller-Matula, Jolanta M; Storey, Robert F.; Tan, Jack W C; Berg, Jurrien M.ten; Valgimigli, Marco; Vandenbriele, Christophe; Lip, Gregory Y H (2023-07-20)Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y purinoceptor 12 (P2Y12) inhibitor (prasugrel or ... -
Impaired Spontaneous/Endogenous Fibrinolytic Status as New Cardiovascular Risk Factor? : JACC Review Topic of the Week
Gorog, Diana; Lip, Gregory Y H (2019-09-10)Endogenous fibrinolysis is a powerful natural defense mechanism against lasting arterial thrombotic occlusion. Recent prospective studies have shown that impaired endogenous fibrinolysis (or hypofibrinolysis) can be detected ... -
Recommendation on the nomenclature for anticoagulants: updated communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Commitee on the Control of Anticoagulation
Barnes, Geoffrey D; Ageno, Walter; Castellucci, Lana A; Chiasakul, Thita; Eslick, Renee; Ferreiro, Jose Luis; Gailani, David; Gorog, Diana; Lip, Gregory Y H; Raffini, Leslie; Rezende, Suely M; Weitz, Jeffrey I; Cuker, Adam (2023-05-30)Oral anticoagulation therapy has evolved beyond vitamin K antagonists to include oral direct thrombin inhibitors and factor Xa inhibitors. Collectively known as “direct oral anticoagulants,” this class of medications ... -
Thrombotic Profile and Oral Anticoagulation in Asian and Non-Asian Patients With Nonvalvular Atrial Fibrillation
Gue, Ying X.; Inoue, Nobutaka; Spinthakis, Nikolaos; Takahara, Hiroyuki; Otsui, Kazunori; Lip, Gregory Y H; Gorog, Diana (2019-12-03) -
Usefulness of the NULL-PLEASE Score to predict 1 survival in out-of hospital cardiac arrest
Gue, Ying; Sayers, Max; Whitby, Benjamin; Kanji, Rahim; Adatia, Krishma; Smith, Robert; Davies, William; Perperoglou, Aris; Potpara, Tatjana; Lip, Gregory Y H; Gorog, Diana (2020-05-07)Purpose: Out-of-hospital cardiac arrest (OHCA) carries a very high mortality even after successful cardiopulmonary resuscitation. Currently, information given to relatives regarding prognosis following resuscitation is ...