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Browsing by Author "Maex, Reinoud"
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The Beneficial Effects of Non-specific Synaptic Plasticity for Pattern Recognition in Auto-associative Memory
Calcraft, L.; Maex, Reinoud; Davey, N.; Steuber, Volker (2011)Poster presented at CNS 2011 -
Characterising the performance of balanced memory networks
Metaxas, A.; Maex, Reinoud; Adams, R.G.; Steuber, Volker; Davey, N. (2013)Poster presented at CNS 2013 -
Decoding of Purkinje cell pauses by deep cerebellar nucleus neurons
Luthman, Johannes; Adams, Roderick; Davey, N.; Maex, Reinoud; Steuber, Volker (BioMed Central (BMC), 2009)The recognition of parallel fibre (PF) input patterns by Purkinje cells has been suggested to underlie cerebellar learning [1,2]. A candidate mechanism for the recognition of PF patterns is the long-term depression (LTD) ... -
Dendritic Morphology Predicts Pattern Recognition Performance in Multi-compartmental Model Neurons with and without Active Conductances
De Sousa, Giseli; Maex, Reinoud; Adams, R.G.; Davey, N.; Steuber, Volker (2015-04-01)In this paper we examine how a neuron’s dendritic morphology can affect its pattern recognition performance. We use two different algorithms to systematically explore the space of dendritic morphologies: an algorithm that ... -
Determinants of associative memory performance in spiking and non-spiking neural networks with different synaptic plasticity regimes
Metaxas, A.; Maex, Reinoud; Adams, R.G.; Steuber, Volker; Davey, N. (2012)Poster presented at CNS 2012 -
Determinants of gain modulation enabled by short-term depression at an inhibitory cerebellar synapse
Bampasakis, Dimitris; Maex, Reinoud; Davey, Neil; Steuber, Volker (2014-07-21)Neurons adapt rapidly the slope, also known as gain, of their input-output function to time-varying conditions. Gain modulation is a prominent mechanism in many brain processes, such as auditory processing and attention ... -
EEG microstates: Functional significance and short-term test-retest reliability
Antonova, Elena; Holding, Martin; Suen, Ho Chak; Sumich, Alex; Maex, Reinoud; Nehaniv, Chrystopher (2022-06-02)EEG microstates, reflecting discrete topographical organization of the EEG signal power, may have clinical relevance; however, their functional significance and test-retest reliability remain unclear. To investigate the ... -
The effect of dendritic morphology on pattern recognition in the presence of active conductances
De Sousa, Giseli; Maex, Reinoud; Adams, R.G.; Davey, N.; Steuber, Volker (2011)Poster presented at CNS 2011 -
Effect of extracellular volume on the energy stored in transmembrane concentration gradients
Maex, Reinoud (2021-10-15)The amount of energy that can be retrieved from a concentration gradient across a membrane separating two compartments depends on the relative size of the compartments. Having a larger low-concentration compartment is in ... -
The effect of non-specific LTD on pattern recognition in cerebellar Purkinje cells
Safaryan, Karen; Maex, Reinoud; Adams, R.G.; Davey, N.; Steuber, Volker (2010)Poster presented at CNS 2010 -
Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine
Graupner, Michael; Maex, Reinoud; Gutkin, Boris (2013-08-15)Nicotine exerts its reinforcing action by stimulating nicotinic acetylcholine receptors (nAChRs) and boosting dopamine (DA) output from the ventral tegmental area (VTA). Recent data have led to a debate about the principal ... -
Energy optimisation predicts the capacity of ion buffering in the brain
Maex, Reinoud (2023-12-16)Neurons store energy in the ionic concentration gradients they build across their cell membrane.The amount of energy stored, and hence the work the ions can do by mixing, can be enhanced by the presence of ion buffers in ... -
Evolution of Dendritic Morphologies Using Deterministic and Nondeterministic Genotype to Phenotype Mapping
Alva, Parimala; De Sousa, Giseli; Torben-Nielsen, Ben; Maex, Reinoud; Adams, Roderick; Davey, N.; Steuber, Volker (Springer Nature, 2013)In this study, two morphological representations in the genotype, a deterministic and a nondeterministic representation, are compared when evolving a neuronal morphology for a pattern recognition task. The deterministic ... -
Impaired facial emotion recognition in patients with ventromedial prefrontal hypoperfusion
Vandekerckhove, Marie; Plessers, Maarten; Van Mieghem, Arno; Beeckmans, Kurt; Van Acker, Frederik; Maex, Reinoud; Markowitsch, Hans; Mariën, Peter; Van Overwalle, Frank (2014-07-01)Empathy refers to our ability to recognize and share emotions by another human being. Impairment may underlie many of the emotional deficits commonly associated with a range of neuropsychiatric and neurological conditions. ... -
An integrator circuit in cerebellar cortex
Maex, Reinoud; Steuber, Volker (2013-09)The brain builds dynamic models of the body and the outside world to predict the consequences of actions and stimuli. A well-known example is the oculomotor integrator, which anticipates the position-dependent elasticity ... -
An Interneuron Circuit Reproducing Essential Spectral Features of Field Potentials
Maex, Reinoud (2018-05-01)Recent advances in engineering and signal processing have renewed the interest in invasive and surface brain recordings, yet many features of cortical field potentials remain incompletely understood. In the present ... -
An Isotonic Model of Neuron Swelling Based on Co-Transport of Salt and Water
Maex, Reinoud (2023-02-07)Neurons spend most of their energy building ion gradients across the cell membrane. During energy deprivation the neurons swell, and the concomitant mixing of their ions is commonly assumed to lead toward a Donnan equilibrium, ... -
Mathematical models of excitability in biological membranes, cells and networks.
Maex, Reinoud (Oxford University Press (OUP), 2010) -
Multiplicative gain modulation arising from inhibitory synaptic plasticity in the cerebellar nuclei
Bampasakis, Dimitris; Maex, Reinoud; Davey, N.; Steuber, Volker (2014)Neurons use the rate of action potentials to encode sensory variables. This makes the output rate as a function of input, also known as input-output (I–O) relationship, a core computational function in neuronal processing. ... -
Non-specific LTD at parallel fibre - Purkinje cell synapses in cerebellar cortex provides robustness against local spatial noise during pattern recognition
Safaryan, Karen; Maex, Reinoud; Adams, R.G.; Davey, N.; Steuber, Volker (2011)Poster presented at CNS 2011