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Browsing by Author "Molleman, A."
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Arachidonic Acid Mediates Non-Capacitative Calcium Entry Evoked by CB1-Cannabinoid Receptor Activation in DDT1MF-2 Smooth Muscle Cells
Demuth, D.G.; Gkoumassi, E.; Droege, M.J.; Dekkers, B.G.J.; Esselink, H.J.; Vanree, R.M.; Parsons, M.; Zaagsma, J.; Molleman, A.; Nelemans, S.A. (2005)Cannabinoid CB1-receptor stimulation in DDT1 MF-2 smooth muscle cells induces a rise in [Ca2+]i, which is dependent on extracellular Ca2+ and modulated by thapsigargin-sensitive stores, suggesting capacitative Ca2+ entry ... -
Calcium release from separate receptor-specific intracellular stores induced by histamine and ATP in a hamster cell line
Denhertog, A.; Hoiting, B.; Molleman, A.; Vandenakker, J.; Duin, M.; Nelemans, A. (1992) -
Cannabinoid signalling (review)
Demuth, D.G.; Molleman, A. (2006) -
Cannabinoid signalling in TNF-alpha induced IL-8 release
Mormina, M. E.; Thakur, S.; Molleman, A.; Whelan, C.J.; Baydoun, A. R. (2006) -
The CB1 cannabinoid receptor antagonist AM251 blocks amphetamine-induced behavioural sensitization together with monoamine changes in the mouse nucleus accumbens and hippocampus
Thiemann, G.; Di Marzo, V.; Molleman, A.; Hasenoehrl, R. (2007)Endogenous cannabinoids modulate the activity of dopamine reward pathways and may play a role in the development of behavioural sensitization to psychostimulants. Here, we investigated the effects of the CB1 cannabinoid ... -
Characteristics of the P2-Purinoceptor- receptor and H1-receptor mediated response in DDT1 MF-2 vas deferens smooth muscle cells
Molleman, A.; Hoiting, B.; Vandenakker, J.; Duin, M.; Nelemans, A.; Denhertog, A. (1990) -
Characterization of the outward rectifying potassium channel in a novel mouse intestinal smooth muscle cell preparation
Molleman, A.; Thuneberg, L.; Huizinga, J.D. (1993) -
Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability
Bailey, C.P.; Manley, S.J.; Watson, W.P.; Wonnacott, S.; Molleman, A.; Little, H.J. (1998)The present study investigated the activity of neurons in the mesolimbic dopamine system after the end of the acute phase of the behavioural signs of ethanol withdrawal in mice. This was designed to provide a comparison ... -
Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption
Bailey, C.P.; Molleman, A.; Little, H.J. (1998)The effects of drugs, previously demonstrated to have a range of effects on the behavioural signs of ethanol withdrawal hyperexcitability, were examined in area CA1 in isolated hippocampal slices prepared after withdrawal ... -
The effects of 9-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis
Jamontt, J.M.; Molleman, A.; Pertwee, R.G.; Parsons, M. (2010)Background and purpose : Cannabis is taken as self-medication by patients with inflammatory bowel disease for symptomatic relief. Cannabinoid receptor agonists decrease inflammation in animal models of colitis, but their ... -
Evidence for both inverse agonism at the cannabinoid CB1 receptor and the lack of an endogenous cannabinoid tone in the rat and guinea-pig isolated ileum myenteric plexus-longitudinal muscle preparation
Makwana, R.; Molleman, A.; Parsons, M. (2010)Background and purpose: Cannabinoid receptor agonists reduce intestinal propulsion in rodents through the CB1 receptor. In addition to its antagonistic activity at this receptor, rimonabant (N-(piperidino)-5-(4-chlorophe ... -
The genetic versus pharmacological invalidation of the cannabinoid CB1 receptor results in differential effects on non-associative memory and forebrain monoamine concentrations in mice
Thiemann, G.; Fletcher, Ben; Ledent, C.; Molleman, A.; Hasenoehrl, R. (2007) -
High-conductance chloride channels generate pacemaker currents in interstitial cells of Cajal
Huizinga, J.D.; Zhu, Y.H.; Ye, J.; Molleman, A. (2002) -
Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids
Ihenetu, K.; Molleman, A.; Parsons, M.; Whelan, C.J. (2003) -
Intercellular communication in smooth muscle
Huizinga, J.D.; Liu, L.W.C.; Blennerhassett, M.G.; Thuneberg, L.; Molleman, A. (1992)The functioning of a group of cells as a tissue depends on intercellular communication; an example is the spread of action potentials through intestinal tissue resulting in synchronized contraction. Recent evidence for ... -
Modulation of the release of endogenous adenosine by cannabinoids in the myenteric preparation of the guinea-pig plexus-longitudinal muscle ileum
Begg, M.; Dale, N.; Llaudet, E.; Molleman, A.; Parsons, M. (2002) -
Modulation of the release of endogenous gamma-aminobutyric acid by cannabinoids in the guinea pig ileum
Begg, M.; Molleman, A.; Parsons, M. (2002) -
Modulation of the α1-Adrenoceptor response in Taenia Ceci of the guinea-pig
Denhertog, A.; Nelemans, S.A.; Vandenakker, J.; Molleman, A. (1989) -
Muscarinic activation of transient inward current and contraction in canine colon circular smooth muscle cells
Molleman, A.; Liu, L.W.C.; Huizinga, J.D. (2001)