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Browsing by Author "Murray, M."
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Determination of halofuginone in bovine plasma by competing-ion high performance liquid chromatography after solid phase extraction
Kinabo, L. D.; McKellar, Quintin; Murray, M. (1989)A high performance liquid chromatography (HPLC) method for the determination of the anticoccidial and antitheilerial drug halofuginone in bovine plasma was developed. Samples were diluted with acetic acid (10%, v/v) and ... -
Different patterns of faecal egg output following infection of Scottish blackface lambs with Ostertagia circumcincta
Stear, M. J.; Bairden, K.; Bishop, S. C.; Duncan, J. L.; Karimi, S. K.; McKellar, Quintin; Murray, M. (1995-08)Faecal nematode egg counts were monitored in 184 Scottish Blackface lambs during natural exposure to a mixed, predominantly Ostertagia circumcincta infection and 12 lambs were selected which showed consistently zero (low ... -
The distribution of faecal nematode egg counts in Scottish Blackface lambs following natural, predominantly Ostertagia circumcincta infection
Stear, M. J.; Bairden, K.; Duncan, J. L.; Gettinby, G.; McKellar, Quintin; Murray, M.; Wallace, D. S. (1995-05)Faecal samples were taken in 2 consecutive years from Scottish Blackface lambs on a commercial farm in central Scotland to examine variation among lambs in the number of nematode eggs in their faeces. Samples were taken ... -
How hosts control worms
Stear, M.J.; Bairden, K.; Duncan, J.L.; Holmes, P.H.; McKellar, Quintin; Park, M.; Strain, S.; Murray, M.; Bishop, S.C.; Gettinby, G. (1997-09-04)Nematodes are a major cause of disease and death in humans, domestic animals and wildlife. Understanding why some individuals suffer severely whereas others exposed to the same infection remain healthy may assist in the ... -
The influence of dietary supplementation with urea on resilience and resistance to infection with Haemonchus contortus
Wallace, D.S.; Bairden, K.; Duncan, J.L.; Eckersall, P.D.; Fishwick, G.; Gill, M.; Holmes, P.H.; McKellar, Quintin; Murray, M.; Parkins, J.J. (1998-01)Previous research has indicated that supplementing an apparently adequate diet with additional protein improves both host resistance and resilience in lambs infected with Haemonchus contortus. The present study tested the ... -
The influence of increased feeding on the susceptibility of sheep to infection with Haemonchus contortus
Wallace, D.S.; Bairden, K.; Duncan, J.L.; Eckersall, P.D.; Fishwick, G.; Holmes, P.H.; McKellar, Quintin; Mitchell, S.; Murray, M.; Parkins, J.J. (1999-10)Previous research has shown that supplementing the diet of growing lambs with urea enhances their ability to withstand gastrointestinal infection with the nematode Haemonchus contortus. This study compared lambs given two ... -
The influence of relative resistance and urea-supplementation on deliberate infection with<i> Teladorsagia circumcincta during winter
Stear, M.J.; Bairden, K.; Duncan, J.L.; Eckersall, P.D.; Fishwick, G.; Graham, P.A.; Holmes, P.H.; McKellar, Quintin; Mitchell, S.; Murray, M. (2000-12-20)The consequences for lambs of infection over the winter with Teladorsagia circumcincta were quantified by deliberate, trickle infection of selected animals at 7 months of age. Infected and control uninfected animals were ... -
Influence of soyabean meal supplementation on the resistance of Scottish Blackface lambs to haemonchosis
Wallace, D.S.; Bairden, K.; Duncan, J.L.; Fishwick, G.; Gill, M.; Holmes, P.H.; McKellar, Quintin; Murray, M.; Parkins, J.J.; Stear, M. (1996-03)Protein supplementation improves the resistance of sheep to haemonchosis. This experiment investigated the Scottish blackface breed to establish whether dietary protein supplementation is still beneficial in a genetically ... -
Influence of supplementation with dietary soyabean meal on resistance to haemonchosis in Hampshire Down lambs
Wallace, D.S.; Bairden, K.; Duncan, J.L.; Fishwick, G.; Gill, M.; Holmes, P.H.; McKellar, Quintin; Murray, M.; Parkins, J.J.; Stear, M.J. (1995-05)The influence of dietary protein supplementation on resistance to haemonchosis was examined in Hampshire down lambs fed either a basal diet or a diet supplemented with soyabean. At seven months of age the lambs were ... -
Local and plasma antibody responses to the parasitic larval stages of the abomasal nematode Ostertagia circumcincta
Sinski, E.; Bairden, K.; Duncan, J. L.; Eisler, M. C.; Holmes, P. H.; McKellar, Quintin; Murray, M.; Stear, M. J. (1995-09)Ovine isotype-specific antibody responses to the parasitic larval stages of the abomasal nematode Ostertagia circumcincta were measured in a simple, indirect enzyme-linked immunosorbent assay. Analysis of variance of ... -
Regulation of egg production, worm burden, worm length and worm fecundity by host responses in sheep infected with Ostertagia circumcincta
Stear, M. J.; Bishop, S. C.; Doligalska, M.; Duncan, J. L.; Holmes, P. H.; Irvine, J.; McCririe, L.; McKellar, Quintin; Sinski, E.; Murray, M. (1995-12)Following infection with Ostertagia circumcincta there was considerable variation in worm burdens, worm size and number of inhibited larvae even among sheep matched for age, sex, breed, farm of origin and history of parasite ... -
Relay bioavailability and toxicity of isometamidium residues : a model for human risk assessment
Kinabo, L. D.; Bogan, J. A.; McKellar, Quintin; Murray, M. (1989)The bioavailability and potential toxicity of the residues of the antitrypanosomal drug isometamidium (ISMM) in bovine tissues were investigated in male Sprague-Dawley rats. They were allowed to feed for 7 and 21 days on ... -
The repeatability of faecal egg counts, peripheral eosinophil counts, and plasma pepsinogen concentrations during deliberate infections with Ostertagia circumcincta
Stear, M.J.; Bishop, S.C.; Duncan, J.L.; McKellar, Quintin; Murray, M. (1995-03)Faecal egg counts, peripheral blood eosinophil counts and plasma pepsinogen concentrations were monitored during 2 successive, deliberate infections in 24 Scottish Blackface sheep. For all 3 techniques, the repeatability ...