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Browsing by Author "Okafor, Osita N"
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Allopurinol as a therapeutic option in cardiovascular disease
Okafor, Osita N; Farrington, K; Gorog, Diana A (2017-04-01)Epidemiological studies indicate that hyperuricaemia is an independent risk factor for cardiovascular disease. Alongside uric acid formation, increased xanthine oxidase activity also results in the formation of oxidative ... -
Endogenous Fibrinolysis : An Important Mediator of Thrombus Formation and Cardiovascular Risk
Okafor, Osita N; Gorog, Diana A (2015-04-28)Most acute cardiovascular events are attributable to arterial thrombosis. Plaque rupture or erosion stimulates platelet activation, aggregation, and thrombosis, whilst simultaneously activating enzymatic processes that ...