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Browsing by Author "Orsolini, Laura"
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The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective
Orsolini, Laura; Chiappini, Stephania; Papanti, Duccio; De Berardis, Domenico; Corkery, John Martin; Schifano, Fabrizio (2019-11-20)The critical spread and dissemination of novel psychoactive substances (NPS), particularly among the most vulnerable youngsters, may pose a further concern about the psychotic trajectories related to the intake of new ... -
Cannabis; epidemiological, neurobiological and psychopathological issues: an update
De Luca, Maria Antonietta; Di Chiara, Gaetano; Cadoni, Cristina; Lecca, Daniele; Orsolini, Laura; Papanti, Duccio; Corkery, John; Schifano, Fabrizio (2017-04-13)Cannabis is the illicit drug with both the largest current levels of consumption and the highest reported lifetime prevalence levels in the world. Across different countries, the prevalence of cannabis use varies according ... -
Characteristics of deaths associated with kratom use
Corkery, John; Streete, Peter; Claridge, Hugh; Goodair, Christine; Papanti, Duccio G.; Orsolini, Laura; Schifano, Fabrizio; Sikka, Kanav; Körber, Sophie; Hendricks, Amy (2019-09-01)Background: Kratom (Mitragyna speciosa Korth) use has increased in Western countries, with a rising number of associated deaths. There is growing debate about the involvement of kratom in these events. Aims: This study ... -
The characteristics of deaths involving kratom in the United Kingdom and elsewhere
Corkery, John; Claridge, Hugh; Goodair, Christine; Papanti, Duccio; Orsolini, Laura; Koerber, Sophie; Schifano, Fabrizio (2016-05-31) -
The consequences of drug misuse on post-marketing surveillance
Schifano, Fabrizio; Papanti, Duccio; Orsolini, Laura; Corkery, John (2016-04-25)Over the past decade, the ‘traditional’ drug scenario has shown significant changes because of the emergence of a range of molecules, e.g. the novel psychoactive substances (NPS), which are either already existing or newly ... -
The "Endless Trip" among the NPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review
Orsolini, Laura; Papanti, Duccio; De Berardis, Domenico; Guirguis, Amira; Corkery, John; Schifano, Fabrizio (2017-11-20)Hallucinogen-persisting perception disorder (HPPD) is a syndrome characterized by prolonged or reoccurring perceptual symptoms, reminiscent of acute hallucinogen effects. HPPD was associated with a broader range of LSD ... -
Evolutionary Considerations on the Emerging Subculture of the E-psychonauts and the Novel Psychoactive Substances : A Comeback to the Shamanism?
Orsolini, Laura; St John-Smith, Paul; McQueen, Daniel; Papanti, Duccio; Corkery, John; Schifano, Fabrizio (2017-12-31)BACKGROUND: Evolutionary research on drug abuse has hitherto been restricted to proximate studies, considering aetiology, mechanism, and ontogeny. However, in order to explain the recent emergency of a new behavioral pattern ... -
From concept(ion) to life after death/the grave: the ‘natural’ history and life-cycle(s) of Novel Psychoactive Substances (NPS)
Orsolini, Laura; Corkery, John; Papanti, Duccio; Schifano, Fabrizio (2017-06-28)A range of information needs should be met in order to better understand and predict the longevity/existence of Novel Psychoactive Substances (NPS). This conceptual paper argues that one way of assessing how long a molecule ... -
Gli Psiconauti: navigatori della mente o sperimentatori chimici?
Orsolini, Laura; Vecchiotti, Roberta; Papanti, Duccio; Valchera, Alessandro; Corkery, John; Schifano, Fabrizio (2016-06-01)Recentemente, all’interno delle comunità online (forum, blog, social network), si sta diffondendo una nuova generazione di consumatori di sostanze, altamente informati ed esperti nel campo delle nuove sostanze psicoattive ... -
An insight into the deep web; why it matters for addiction psychiatry?
Orsolini, Laura; Papanti, Duccio; Corkery, John; Schifano, Fabrizio (2017-06-28)ABSTRACT Objective. Nowadays, the web is rapidly spreading, playing a significant role in the marketing/sale/distribution of ‘quasi’ legal drugs, hence facilitating continuous changes in drug scenarios. The easily renewable ... -
An investigation into the relationship(s) between the different chemical classes of synthetic cathinones and their effects: desired, adverse and toxic
Corkery, John; Guirguis, Amira; Orsolini, Laura; Papanti, Duccio; Schifano, Fabrizio (2017-10-24) -
Is there a potential of misuse for Magnolia officinalis compounds/metabolites?
Schifano, Fabrizio; Guarino, Valentina; Papanti, Duccio G.; Baccarin, Jacopo; Orsolini, Laura; Corkery, John M. (2017-05-18)Objective: Magnolia bark contains magnolol, metabolized to tetrahydromagnolol and honokiol, with both GABA-ergic/cannabimimetic activities, hence of possible attraction to vulnerable individuals/recreational misusers. ... -
Lurasidone in the Treatment of Bipolar Depression: : Systematic Review of Systematic Reviews
Fornaro, Michele; De Berardis, Domenico; Perna, Giampaolo; Solmi, Marco; Veronese, Nicola; Orsolini, Laura; Buonaguro, Elisabetta Filomena; Iasevoli, Felice; Köhler, Cristiano André; Carvalho, André Ferrer; De Bartolomeis, Andrea (2017-05-09)Introduction. A burgeoning number of systematic reviews considering lurasidone in the treatment of bipolar depression have occurred since its Food and Drug Administration extended approval in 2013. While a paucity of ... -
Mind Navigators of Chemicals' Experimenters? A Web-Based Description of E-Psychonauts
Orsolini, Laura; Papanti, Gabriele Duccio; Francesconi, Giulia; Schifano, Fabrizio (2015-05-12)Within online drug fora communities, there are some "educated and informed" users who can somehow provide reliable information on psychoactive compounds and combinations. These users, also called "e-psychonauts," may possess ... -
New psychoactive substances (NPS), psychedelic experiences, and dissociation: clinical and clinical pharmacological issues
Schifano, Fabrizio; Napoletano, Flavia; Chiappini, Stephania; Orsolini, Laura; Guirguis, Amira; Corkery, John Martin; Bonaccorso, Stefania; Ricciardi, Angelo; Scherbaum, Norbert; vento, alessandro (2019-04-23)Purpose of the review: A significant increase in the number, type, and availability of new psychoactive substances (NPS) with dissociative and psychedelic potential has occurred worldwide over the last few decades. Psychedelic ... -
New Psychoactive Substances and suicidality: a systematic review of the current literature.
Chiappini, Stefania; Mosca, Alessio; Miuli, A.; Santovito, Monica Chiara; Orsolini, Laura; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; Martinotti, Giovanni; di Giannantonio, Massimo; Schifano, Fabrizio (2021-06-06)Background and Objectives: Over the past twenty years a large number of New Psychoactive Substances (NPS) has entered and modified the recreational drug scene. Their intake has been associated with health-related risks, ... -
'New/Designer Benzodiazepines': an analysis of the literature and psychonauts’ trip reports
Orsolini, Laura; Corkery, John; Chiappini, Stephania; Guirguis, Amira; Vento, Alessandro; De Berardis, Domenico; Papanti, Duccio; Schifano, Fabrizio (2020-01-10)Background: NPS belonging to the benzodiazepine (BZD) class, e.g., ‘legal/designer BZDs’/‘research chemicals’, have recently emerged in the drug (mainly online/virtual) market. Objective: While certain NPS belonging to the ... -
Novel psychoactive substances
Orsolini, Laura; Papanti, Duccio; Vecchiotti, Roberta; Valchera, Alessandro; Corkery, John; Schifano, Fabrizio (2016-03) -
Novel psychoactive substances of interest for psychiatry
Schifano, Fabrizio; Orsolini, Laura; Papanti, Duccio; Corkery, John (2015-02)Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, ... -
Novel Psychoactive Substances: : the pharmacology of stimulants and hallucinogens
Schifano, Fabrizio; Papanti, Duccio; Orsolini, Laura; Corkery, John (2016-07-02)There are increasing levels of concern relating to the rapidly evolving novel psychoactive substances/NPS and web markets’ scenarios. The paper aims at providing an overview of the clinical pharmacological issues related ...