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Statistical evaluation of influence of xanthan gum and guar gum blends on dipyridamole release from floating matrix tablets

dc.contributor.authorPatel, Viral F.
dc.contributor.authorPatel, Natavarlal M.
dc.date.accessioned2013-09-17T07:30:17Z
dc.date.available2013-09-17T07:30:17Z
dc.date.issued2007
dc.identifier.citationPatel , V F & Patel , N M 2007 , ' Statistical evaluation of influence of xanthan gum and guar gum blends on dipyridamole release from floating matrix tablets ' , Drug Development and Industrial Pharmacy , vol. 33 , no. 3 , pp. 327-34 . https://doi.org/10.1080/03639040601050155
dc.identifier.issn0363-9045
dc.identifier.otherPURE: 308565
dc.identifier.otherPURE UUID: bb6d9e28-2b5d-48da-9ade-511b44462713
dc.identifier.otherPubMed: 17454065
dc.identifier.otherScopus: 34247467447
dc.identifier.urihttp://hdl.handle.net/2299/11572
dc.description.abstractThe present investigation explored the use of xanthan gum and guar gum for development of floating drug delivery system of dipyridamole using factorial design approach. The content of polymer blends (X(1)) and ratio of xanthan gum to guar gum (X(2)) were selected as independent variables. The diffusion exponent (n), release rate constant (k), percentage drug release at 1 hr (Q(1)) and 6 hr (Q(6)) were selected as dependent variables. Tablets of all batches had desired buoyancy characteristics. Multiple regression analysis with two way ANOVA revealed that both the factors had statistically significant influence on the response studied (pen
dc.format.extent8
dc.language.isoeng
dc.relation.ispartofDrug Development and Industrial Pharmacy
dc.subjectAnalysis of Variance
dc.subjectDiffusion
dc.subjectDipyridamole
dc.subjectDrug Carriers
dc.subjectDrug Delivery Systems
dc.subjectFactor Analysis, Statistical
dc.subjectGalactans
dc.subjectMannans
dc.subjectPlant Gums
dc.subjectPolysaccharides, Bacterial
dc.subjectTablets
dc.subjectVasodilator Agents
dc.titleStatistical evaluation of influence of xanthan gum and guar gum blends on dipyridamole release from floating matrix tabletsen
dc.contributor.institutionDepartment of Pharmacy
dc.contributor.institutionPharmaceutics
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionBioadhesive Drug Delivery Group
dc.contributor.institutionPharmaceutical Analysis and Product Characterisation
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.description.statusPeer reviewed
rioxxterms.versionofrecordhttps://doi.org/10.1080/03639040601050155
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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