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The Style and Extent of Younger Dryas Glaciation in the English Lake District
(2024-08-28)Reconstructions of the maximal extent of Younger Dryas (~12.9-11.7 Ka BP) glaciers in the English Lake District have changed considerably over the past 60 years. Early interpretations assumed an alpine-style glaciation, ... -
Building a Research Ready Workforce in a Community NHS Trust
(2024-09-23)Introduction: The Department of Health and Social Care sets out a vision to create a research positive culture across the NHS where all staff feel empowered and supported to participate in clinical research delivery. ... -
The Isolated Anomaly: Representations of the Austro-Hungarian Empire in the Anglosphere Media, 1892-1914
(2024-07-20)This dissertation adopts a comprehensive approach, combining a dual perspective that delves into the intricate relationship between foreign policy and domestic politics. It focuses on a careful analysis of six selected ... -
Understanding the Role of BMP Signalling in the Formation of Neural Circuits in the Chick Embryo
(2024-08-15)Regenerative cell-based therapies for spinal cord injuries (SCI) will benefit from a deeper understanding of proprioceptive neural circuit formation in the developing embryo. The function of sensory interneurons, such ... -
A Life Course Approach Investigating the Mechanisms Underlying the Relationship between Loneliness and Health and Wellbeing in Retired Older Adults, using Mixed Methods
(2024-04-24)Loneliness, or the negatively perceived discrepancy between desired and realised social relationships, has long been considered detrimental to health. This research sought to discover what is it that allows loneliness ... -
A Network Security Solution to Manage and Increase Effectiveness of Servers
(2024-06-24)In today's digital landscape, the proliferation of cyber threats, particularly Denial-of-Service (DoS) attacks, underscores the critical need for advanced server monitoring systems. Traditional monitoring tools, while ... -
The Development and Validation of the HPLC Method for Determination of Artesunate and Amodiaquine in Novel Antimalarial Formulations
(2024-07-03)ASAQ combination drug used in treating malaria is bitter in taste, resulting in poor adherence and difficulty in swallowing by children. To mitigate this issue, taste masking is achieved by coating the drug with polymers ... -
Design and Optimisation of a Modular Industrial Air Scrubber Utilising Surfactant Absorption Technology
(2024-01-19)A novel air scrubbing technology using a misting application and water additives has successfully demonstrated the capability of scrubbing H2S at a water treatment plant. The air scrubber design utilises a solution of ... -
Exploring Aquaponics Systems as part of Food Planning and Environmental Management Strategy, Policy and Sustainable Placemaking: Examining Chinese and UK Food Growing Project Case Studies
(2023-08-10)This study aims to analyse several factors concerning the role of aquaponics in contributing to food availability in urban, suburban, and rural areas from the perspective of food planning and environmental management ... -
Construction and Analysis of Multi-Index Financial Model
(2023-03-23)This paper presents an empirical study of the expansion of the single-index model into a multi-index model with a careful selection of indices. A total of 91 multi-index models were built and tested using advanced statistical ... -
The Properties of Hitherto Unidentified Radio Sources in the MIGHTEE Survey
(2023-04-04)Radio astronomy is a pioneering branch of astronomy research - new radio surveys have gathered a lot of attention in the last few years, due to the huge expansion in capabilities of new radio facilities, with new ... -
The Nature of Compact Sources Selected by LOFAR
(2023-04-24)Radio-loud active galactic nuclei (RLAGN) produce jets on large scales heating their local environments and preventing the hot phase of baryonic matter from cooling hence slowing or halting galaxy formation and evolution; ... -
Characterisation of Peripheral Neuropathy and Neuronal and Endothelial Markers of Neuropathic Pain: a Comparative Study Across Preclinical Models of Neuropathic Pain
(2022-11-07)Neuropathic pain is pain caused by a lesion or disease to the somatosensory pathways. A leading cause is diabetic peripheral neuropathy which effects over half of all diabetic patients. This neuronal damage commonly leads ... -
Regulation of Receptors Siglec-11 and Siglec-15 by MicroRNAs and their Overall Effect on Glioblastoma
(2022-11-07)Introduction: Glioblastoma is a fast growing and aggressive type of brain tumour. It is the most common type of brain tumour in adults. Although there are developments in current therapies, patient outcomes remain poor. ... -
Deletion of Prophages in Clostridioides difficile
(2022-04-14)Clostridioides difficile (C. difficile) formally known as Clostridium difficile, is a Gram-positive spore forming anaerobe responsible for almost all cases of pseudomembranous colitis and is implicated in 25-33% of antibiotic ... -
Simultaneous Far-infrared and X-ray Monitoring of Young Stellar Objects in the Coronet Cluster
(2022-03-02)Context: Multi-wavelength time domain analysis of Young Stellar Objects (YSOs) is a relatively new method within star formation research which may lead to better constraints on fundamental star formation processes. Such ... -
Accretion Disc Structure of Supermassive Stars Formed by Collisions
(2022-03-08)Globular clusters (GCs) display large variations in light elements; the main one being O-Na, C-N and Mg-Al anticorrelations. Additionally most GCs demonstrate multiple sequences in the colour-magnitude diagram, proving ... -
Field-based Determination of Critical Power and Critical Speed Among Recreational Runners
(2022-01-24)Background Critical power (CP) is a highly regarded threshold, delineating the boundary between heavy and severe intensities of exercise. Determination of CP has long been hindered by testing protocols that are time ... -
Combination of Multi-Modal Imaging and Neurophysiology to Improve Targeting Accuracy and Outcome in Deep Brain Stimulation for Movement Disorders
(2021-10-06)A study was conducted to observe the positioning of two sets of electrodes in fourteen patients with Parkinson’s disease (PD). The purpose was to potentially optimise electrode positioning and parameters with the goal of ... -
Explaining Time's Direction
(2021-10-27)The characteristics of the tenseless theory of time do not account for the direction of time that we experience at a global or local level. There have been several attempts by scientists, and philosophers, to account for ...