Browsing Masters Theses by Author "Ramdeen-Lessey, Klis Keith"
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Design and Synthesis of Novel pH-Sensitive Anticancer Drug and Efflux Pump Inhibitor Conjugates
Ramdeen-Lessey, Klis Keith (2020-10-27)Resistance to anti-cancer therapies has proven a challenge for effective treatments. Efflux pumps when overexpressed in cancer cells, eject drugs from the cell, rendering them ineffective. The pH of cancer cells is generally ...