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Characterisation of Peripheral Neuropathy and Neuronal and Endothelial Markers of Neuropathic Pain: a Comparative Study Across Preclinical Models of Neuropathic Pain
(2022-11-07)
Neuropathic pain is pain caused by a lesion or disease to the somatosensory pathways. A leading cause is diabetic peripheral neuropathy which effects over half of all diabetic patients. This neuronal damage commonly leads ...
Regulation of Receptors Siglec-11 and Siglec-15 by MicroRNAs and their Overall Effect on Glioblastoma
(2022-11-07)
Introduction: Glioblastoma is a fast growing and aggressive type of brain tumour. It is the most common type of brain tumour in adults. Although there are developments in current therapies, patient outcomes remain poor. ...
Deletion of Prophages in Clostridioides difficile
(2022-04-14)
Clostridioides difficile (C. difficile) formally known as Clostridium difficile, is a Gram-positive spore forming anaerobe responsible for almost all cases of pseudomembranous colitis and is implicated in 25-33% of antibiotic ...
Accretion Disc Structure of Supermassive Stars Formed by Collisions
(2022-03-08)
Globular clusters (GCs) display large variations in light elements; the main one
being O-Na, C-N and Mg-Al anticorrelations. Additionally most GCs demonstrate
multiple sequences in the colour-magnitude diagram, proving ...
Simultaneous Far-infrared and X-ray Monitoring of Young Stellar Objects in the Coronet Cluster
(2022-03-02)
Context: Multi-wavelength time domain analysis of Young Stellar Objects (YSOs) is a
relatively new method within star formation research which may lead to better constraints
on fundamental star formation processes. Such ...
Field-based Determination of Critical Power and Critical Speed Among Recreational Runners
(2022-01-24)
Background
Critical power (CP) is a highly regarded threshold, delineating the boundary between heavy and severe intensities of exercise. Determination of CP has long been hindered by testing protocols that are time ...
Explaining Time's Direction
(2021-10-27)
The characteristics of the tenseless theory of time do not account for the direction of time that we experience at a global or local level. There have been several attempts by scientists, and philosophers, to account for ...
Combination of Multi-Modal Imaging and Neurophysiology to Improve Targeting Accuracy and Outcome in Deep Brain Stimulation for Movement Disorders
(2021-10-06)
A study was conducted to observe the positioning of two sets of electrodes in fourteen patients with Parkinson’s disease (PD). The purpose was to potentially optimise electrode positioning and parameters with the goal of ...
Moritz Schlick on the Value of Play
(2021-08-19)
The focus of this essay is Moritz Schlick’s On the Meaning of Life. Schlick wrote On the Meaning of Life in 1927 and hoped to push back against pessimist currents of thought that were popular at the time by using the ...
Dietary Habits and Participant-Led Adaptations to Diet for Pain Management in Fibromyalgia Sufferers: a Cross-Sectional Study
(2021-05-27)
Abstract
Fibromyalgia is a disorder characterised by chronic widespread pain that has been present for more than 3 months and can be elicited by palpitation of specific touch points. It is associated with a wide range ...