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dc.contributor.authorSridharan, Sivakumar
dc.contributor.authorBerdeprado, Jocelyn
dc.contributor.authorVilar, Enric
dc.contributor.authorRoberts, Justin
dc.contributor.authorFarrington, Ken
dc.date.accessioned2015-04-13T12:48:55Z
dc.date.available2015-04-13T12:48:55Z
dc.date.issued2014-08-18
dc.identifier.citationSridharan , S , Berdeprado , J , Vilar , E , Roberts , J & Farrington , K 2014 , ' A self-report comorbidity questionnaire for haemodialysis patients ' , BMC Nephrology , vol. 15 , no. 1 , 134 . https://doi.org/10.1186/1471-2369-15-134
dc.identifier.otherPURE: 8390547
dc.identifier.otherPURE UUID: 9ced955d-d8e6-41ab-b606-8c70aa80a47e
dc.identifier.otherScopus: 84906923952
dc.identifier.otherPubMed: 25135668
dc.identifier.urihttp://hdl.handle.net/2299/15752
dc.descriptionThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated
dc.description.abstractBackground: Patients with end-stage renal disease (ESRD) have multiple comorbid conditions. Obtaining comorbidity data from medical records is cumbersome. A self-report comorbidity questionnaire is a useful alternative. Our aim in this study was to examine the predictive value of a self-report comorbidity questionnaire in terms of survival in ESRD patients. Methods. We studied a prospective cross-sectional cohort of 282 haemodialysis (HD) patients in a single centre. Participants were administered the self-report questionnaire during an HD session. Information on their comorbidities was subsequently obtained from an examination of the patient's medical records. Levels of agreement between parameters derived from the questionnaire, and from the medical records, were examined. Participants were followed-up for 18 months to collect survival data. The influence on survival of comorbidity scores derived from the self-report data (the Composite Self-report Comorbidity Score [CSCS]) and from medical records data - the Charlson Comorbidity Index [CCI] were compared. Results: The level of agreement between the self-report items and those obtained from medical records was almost perfect with respect the presence of diabetes (Kappa score κ 0.97), substantial for heart disease and cancer (κ 0.62 and κ 0.72 respectively), moderate for liver disease (κ 0.51), only fair for lung disease, arthritis, cerebrovascular disease, and depression (κ 0.34, 0.35, 0.34 and 0.29 respectively). The CSCS was strongly predictive of survival in regression models (Nagelkerke R2value 0.202), with a predictive power similar to that of the CCI (Nagelkerke R2value 0.211). The influences of these two parameters were additive in the models - suggesting that these parameters make different contributions to the assessment of comorbidity. Conclusion: This self-report comorbidity questionnaire is a viable tool to collect comorbidity data and may have a role in the prediction of short-term survival in patients with end-stage renal disease on haemodialysis. Further work is required in this setting to refine the tool and define its role.en
dc.language.isoeng
dc.relation.ispartofBMC Nephrology
dc.rightsOpen
dc.subjectComorbidity
dc.subjectEnd-stage renal disease
dc.subjectHaemodialysis
dc.subjectQuestionnaire
dc.subjectSurvival
dc.subjectNephrology
dc.subjectMedicine(all)
dc.titleA self-report comorbidity questionnaire for haemodialysis patientsen
dc.contributor.institutionCentre for Postgraduate Medicine
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionPostgraduate Medicine
dc.contributor.institutionHealth Services and Medicine
dc.contributor.institutionPharmacology and Clinical Science Research
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Life and Medical Sciences
dc.description.versiontypeFinal Published version
dcterms.dateAccepted2014-08-18
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1186/1471-2369-15-134
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstypeOpen


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