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dc.contributor.authorMengoni, Silvana
dc.contributor.authorGates, Robert
dc.contributor.authorParkes, Georgina
dc.contributor.authorWellsted, David
dc.contributor.authorBarton, Garry
dc.contributor.authorRing, Howard
dc.contributor.authorKhoo, Mary Ellen
dc.contributor.authorMonji-Patel, Deela
dc.contributor.authorFriedli, Karin
dc.contributor.authorZia, Asif
dc.contributor.authorDurand, Marie-Anne
dc.date.accessioned2016-12-16T12:02:49Z
dc.date.available2016-12-16T12:02:49Z
dc.date.issued2016-11-10
dc.identifier.citationMengoni , S , Gates , R , Parkes , G , Wellsted , D , Barton , G , Ring , H , Khoo , M E , Monji-Patel , D , Friedli , K , Zia , A & Durand , M-A 2016 , ' Wordless intervention for people with epilepsy and learning disabilities (WIELD): A randomised controlled feasibility trial ' , BMJ Open , vol. 6 , e012993 . https://doi.org/10.1136/bmjopen-2016-012993
dc.identifier.issn2044-6055
dc.identifier.otherPURE: 10293438
dc.identifier.otherPURE UUID: fbe89122-e6ec-4e75-aebb-0b413d94fb14
dc.identifier.otherScopus: 84995426648
dc.identifier.urihttp://hdl.handle.net/2299/17430
dc.descriptionThis is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ Silvana E. Mengoni, et al., 'Wordless intervention for people with epilepsy and learnign disabilities (WIELD): a randomised controlled feasibility trial', BMJ Open, Vol 6 (11), e012993, November 2016. Published by BMJ Publishing Group Limited. The version of record is available at doi: 10.1136/bmjopen-2016- 012993
dc.description.abstractObjective To investigate the feasibility of a full-scale randomised controlled trial of a picture booklet to improve quality of life for people with epilepsy and learning disabilities. Trial design A randomised controlled feasibility trial. Randomisation was not blinded and was conducted using a centralised secure database and a blocked 1:1 allocation ratio. Setting Epilepsy clinics in 1 English National Health Service (NHS) Trust. Participants Patients with learning disabilities and epilepsy who had: a seizure within the past 12 months, meaningful communication and a carer with sufficient proficiency in English. Intervention Participants in the intervention group used a picture booklet with a trained researcher, and a carer present. These participants kept the booklet, and were asked to use it at least twice more over 20 weeks. The control group received treatment as usual, and were provided with a booklet at the end of the study. Outcome measures 7 feasibility criteria were used relating to recruitment, data collection, attrition, potential effect on epilepsy-related quality of life (Epilepsy and Learning Disabilities Quality of Life Scale, ELDQOL) at 4-week, 12-week and 20-week follow-ups, feasibility of methodology, acceptability of the intervention and potential to calculate cost-effectiveness. Outcome The recruitment rate of eligible patients was 34% and the target of 40 participants was reached. There was minimal missing data and attrition. An intention-to-treat analysis was performed; data from the outcome measures suggest a benefit from the intervention on the ELDQOL behaviour and mood subscales at 4 and 20 weeks follow-up. The booklet and study methods were positively received, and no adverse events were reported. There was a positive indication of the potential for a cost-effectiveness analysis. Conclusions All feasibility criteria were fully or partially met, therefore confirming feasibility of a definitive trial. Trial registration number ISRCTN80067039.en
dc.language.isoeng
dc.relation.ispartofBMJ Open
dc.rightsOpen
dc.subjectepilepsy
dc.subjectpsychology
dc.subjectlearning disability
dc.subjectintellectual disability
dc.subjectintervention
dc.subjectself-management
dc.subjectfeasibility studies
dc.titleWordless intervention for people with epilepsy and learning disabilities (WIELD): A randomised controlled feasibility trialen
dc.contributor.institutionCentre for Lifespan and Chronic Illness Research
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Psychology and Sports Sciences
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionSocial Work, Mental Health and Learning Disabilities
dc.contributor.institutionPsychology
dc.contributor.institutionHealth and Clinical Psychology group
dc.contributor.institutionHealth Services and Medicine
dc.contributor.institutionBehaviour Change in Health and Business
dc.contributor.institutionHealth Research Methods Unit
dc.contributor.institutionCentre for Research in Psychology and Sport Sciences
dc.contributor.institutionSchool of Health and Social Work
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Life and Medical Sciences
dc.relation.schoolSchool of Health and Social Work
dc.description.versiontypeFinal Published version
dcterms.dateAccepted2016-11-10
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1136/bmjopen-2016-012993
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.rights.accesstypeOpen


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