dc.contributor.author | Christensen, Luisa | |
dc.contributor.author | Turner, Rob | |
dc.contributor.author | Weaver, Sean | |
dc.contributor.author | Caserta, Francesco | |
dc.contributor.author | Long, Lisa | |
dc.contributor.author | Ghannoum, Mahmoud | |
dc.contributor.author | Brown, Marc | |
dc.date.accessioned | 2018-02-02T13:43:08Z | |
dc.date.available | 2018-02-02T13:43:08Z | |
dc.date.issued | 2017-07-01 | |
dc.identifier.citation | Christensen , L , Turner , R , Weaver , S , Caserta , F , Long , L , Ghannoum , M & Brown , M 2017 , ' Evaluation of the ability of a novel miconazole formulation to penetrate nail by using three in vitro nail models ' , Antimicrobial Agents and Chemotherapy , vol. 61 , no. 7 , e02554-16 . https://doi.org/10.1128/AAC.02554-16 | |
dc.identifier.issn | 0066-4804 | |
dc.identifier.uri | http://hdl.handle.net/2299/19716 | |
dc.description | This document is the Accepted Manuscript of the following article: Luisa Christensen, Rob Turner, Sean Weaver, Francesco Caserta, Lisa Long, Mahmoud Ghannoum, and Marc Brown, ‘Evaluation of the Ability of a Novel Miconazole Formulation To Penetrate Nail by Using Three In Vitro Nail Models’, Antimicrobial Agents and Chemotherapy, Vol. 61 (7): e02554-16, July 2017. The final, published version is available online at DOI: https://doi.org/10.1128/AAC.02554-16. | |
dc.description.abstract | In an effort to increase the efficacy of topical medications for treating onychomycosis, several new nail penetration enhancers were recently developed. In this study, the ability of 10% (wt/wt) miconazole nitrate combined with a penetration enhancer formulation to permeate the nail is demonstrated by the use of a selection of in vitro nail penetration assays. These assays included the bovine hoof, TurChub zone of inhibition, and infected-nail models. | en |
dc.format.extent | 754034 | |
dc.language.iso | eng | |
dc.relation.ispartof | Antimicrobial Agents and Chemotherapy | |
dc.subject | Miconazole | |
dc.subject | Onychomycosis | |
dc.subject | Topical | |
dc.subject | Pharmacology | |
dc.subject | Pharmacology (medical) | |
dc.subject | Infectious Diseases | |
dc.title | Evaluation of the ability of a novel miconazole formulation to penetrate nail by using three in vitro nail models | en |
dc.contributor.institution | Centre for Research into Topical Drug Delivery and Toxicology | |
dc.contributor.institution | University of Hertfordshire | |
dc.description.status | Peer reviewed | |
dc.date.embargoedUntil | 2018-04-01 | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85021676508&partnerID=8YFLogxK | |
rioxxterms.versionofrecord | 10.1128/AAC.02554-16 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |