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dc.contributor.authorChristensen, Luisa
dc.contributor.authorTurner, Rob
dc.contributor.authorWeaver, Sean
dc.contributor.authorCaserta, Francesco
dc.contributor.authorLong, Lisa
dc.contributor.authorGhannoum, Mahmoud
dc.contributor.authorBrown, Marc
dc.date.accessioned2018-02-02T13:43:08Z
dc.date.available2018-02-02T13:43:08Z
dc.date.issued2017-07-01
dc.identifier.citationChristensen , L , Turner , R , Weaver , S , Caserta , F , Long , L , Ghannoum , M & Brown , M 2017 , ' Evaluation of the ability of a novel miconazole formulation to penetrate nail by using three in vitro nail models ' Antimicrobial Agents and Chemotherapy , vol. 61 , no. 7 , e02554-16 . https://doi.org/10.1128/AAC.02554-16
dc.identifier.issn0066-4804
dc.identifier.otherPURE: 13308673
dc.identifier.otherPURE UUID: cd55acca-f3e8-4a89-a6de-8edaa3a4e0fe
dc.identifier.otherScopus: 85021676508
dc.identifier.urihttp://hdl.handle.net/2299/19716
dc.descriptionThis document is the Accepted Manuscript of the following article: Luisa Christensen, Rob Turner, Sean Weaver, Francesco Caserta, Lisa Long, Mahmoud Ghannoum, and Marc Brown, ‘Evaluation of the Ability of a Novel Miconazole Formulation To Penetrate Nail by Using Three In Vitro Nail Models’, Antimicrobial Agents and Chemotherapy, Vol. 61 (7): e02554-16, July 2017. The final, published version is available online at DOI: https://doi.org/10.1128/AAC.02554-16.
dc.description.abstractIn an effort to increase the efficacy of topical medications for treating onychomycosis, several new nail penetration enhancers were recently developed. In this study, the ability of 10% (wt/wt) miconazole nitrate combined with a penetration enhancer formulation to permeate the nail is demonstrated by the use of a selection of in vitro nail penetration assays. These assays included the bovine hoof, TurChub zone of inhibition, and infected-nail models.en
dc.language.isoeng
dc.relation.ispartofAntimicrobial Agents and Chemotherapy
dc.rights/dk/atira/pure/core/openaccesspermission/embargoed
dc.subjectMiconazole
dc.subjectOnychomycosis
dc.subjectTopical
dc.subjectPharmacology
dc.subjectPharmacology (medical)
dc.subjectInfectious Diseases
dc.titleEvaluation of the ability of a novel miconazole formulation to penetrate nail by using three in vitro nail modelsen
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionUniversity of Hertfordshire
dc.description.statusPeer reviewed
dc.date.embargoedUntil2018-04-01
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85021676508&partnerID=8YFLogxK
dc.description.versiontypeFinal Accepted Version
dcterms.dateAccepted2017-04-14
rioxxterms.versionAM
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1128/AAC.02554-16
rioxxterms.licenseref.startdate2018-04-01+01:00
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue
herts.date.embargo2018-04-01+01:00
herts.rights.accesstypeopenAccess


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