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dc.contributor.authorChilcott, Robert
dc.contributor.authorKassouf, Nick
dc.contributor.authorSyed, Sara
dc.contributor.authorLarner, Joanne
dc.contributor.authorAmlôt, Richard
dc.date.accessioned2018-05-17T15:39:04Z
dc.date.available2018-05-17T15:39:04Z
dc.date.issued2017-02-02
dc.identifier.citationChilcott , R , Kassouf , N , Syed , S , Larner , J & Amlôt , R 2017 , ' Evaluation of absorbent materials for use as ad hoc dry decontaminants during mass casualty incidents as part of the UK’s Initial Operational Response (IOR) ' , PLoS ONE , vol. 12 , no. 2 , e0170966 . https://doi.org/10.1371/journal.pone.0170966
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/2299/20055
dc.descriptionCopyright: © 2017 Kassouf et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.description.abstractThe UK's Initial Operational Response (IOR) is a revised process for the medical management of mass casualties potentially contaminated with hazardous materials. A critical element of the IOR is the introduction of immediate, on-scene disrobing and decontamination of casualties to limit the adverse health effects of exposure. Ad hoc cleansing of the skin with dry absorbent materials has previously been identified as a potential means of facilitating emergency decontamination. The purpose of this study was to evaluate the in vitro oil and water absorbency of a range of materials commonly found in the domestic and clinical environments and to determine the effectiveness of a small, but representative selection of such materials in skin decontamination, using an established ex vivo model. Five contaminants were used in the study: methyl salicylate, parathion, diethyl malonate, phorate and potassium cyanide. In vitro measurements of water and oil absorbency did not correlate with ex vivo measurements of skin decontamination. When measured ex vivo, dry decontamination was consistently more effective than a standard wet decontamination method ("rinse-wipe-rinse") for removing liquid contaminants. However, dry decontamination was ineffective against particulate contamination. Collectively, these data confirm that absorbent materials such as wound dressings and tissue paper provide an effective, generic capability for emergency removal of liquid contaminants from the skin surface, but that wet decontamination should be used for non-liquid contaminants.en
dc.format.extent15
dc.format.extent3079476
dc.language.isoeng
dc.relation.ispartofPLoS ONE
dc.titleEvaluation of absorbent materials for use as ad hoc dry decontaminants during mass casualty incidents as part of the UK’s Initial Operational Response (IOR)en
dc.contributor.institutionDepartment of Pharmacy, Pharmacology and Postgraduate Medicine
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionPharmaceutics
dc.contributor.institutionToxicology
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionCentre for Applied Clinical, Health and Care Research (CACHE)
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.description.statusPeer reviewed
rioxxterms.versionofrecord10.1371/journal.pone.0170966
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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