dc.contributor.author | Jolly, Elaine C | |
dc.contributor.author | Clatworthy, Menna R | |
dc.contributor.author | Lawrence, Christopher | |
dc.contributor.author | Nathan, Paul D | |
dc.contributor.author | Farrington, Ken | |
dc.date.accessioned | 2018-10-04T01:08:05Z | |
dc.date.available | 2018-10-04T01:08:05Z | |
dc.date.issued | 2009-04-28 | |
dc.identifier.citation | Jolly , E C , Clatworthy , M R , Lawrence , C , Nathan , P D & Farrington , K 2009 , ' Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis ' , NDT Plus , vol. 2 , no. 4 , pp. 300-2 . https://doi.org/10.1093/ndtplus/sfp048 | |
dc.identifier.issn | 1753-0784 | |
dc.identifier.other | PURE: 13325358 | |
dc.identifier.other | PURE UUID: 256d63f2-9699-41f2-b8da-eb215ef7b177 | |
dc.identifier.other | PubMed: 25984021 | |
dc.identifier.other | PubMedCentral: PMC4421243 | |
dc.identifier.other | Scopus: 77955976757 | |
dc.identifier.uri | http://hdl.handle.net/2299/20681 | |
dc.description.abstract | Targeted immune-modulating agents are entering clinical practice in many specialties, providing novel therapeutic possibilities but introducing new potential toxicities. We present the first reported case, to our knowledge, of immune-mediated nephritis following the administration of Tremelimumab (CP-675, 206), an anti-cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) monoclonal antibody. High-dose steroid therapy led to a rapid improvement in renal function, avoiding the need for renal replacement therapy. | en |
dc.format.extent | 3 | |
dc.language.iso | eng | |
dc.relation.ispartof | NDT Plus | |
dc.subject | Journal Article | |
dc.title | Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis | en |
dc.contributor.institution | Basic and Clinical Science Unit | |
dc.contributor.institution | Centre for Health Services and Clinical Research | |
dc.contributor.institution | Department of Pharmacy, Pharmacology and Postgraduate Medicine | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.description.status | Peer reviewed | |
rioxxterms.version | VoR | |
rioxxterms.versionofrecord | https://doi.org/10.1093/ndtplus/sfp048 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |