dc.contributor.author | Pisarska, Agnieszka | |
dc.contributor.author | Deluca, Paolo | |
dc.contributor.author | Demetrovics, Zsolt | |
dc.contributor.author | Corkery, John | |
dc.contributor.author | Moskalewicz, Jacek | |
dc.contributor.author | ReDNet Group | |
dc.contributor.author | Corazza, Ornella | |
dc.contributor.author | Corkery, John | |
dc.contributor.author | Stair, Jacqueline | |
dc.contributor.author | Fergus, Suzanne | |
dc.contributor.author | Pezzolesi, Cinzia | |
dc.contributor.author | Schifano, Fabrizio | |
dc.date.accessioned | 2020-03-22T01:20:42Z | |
dc.date.available | 2020-03-22T01:20:42Z | |
dc.date.issued | 2020-02-18 | |
dc.identifier.citation | Pisarska , A , Deluca , P , Demetrovics , Z , Corkery , J , Moskalewicz , J , ReDNet Group , , Corazza , O , Corkery , J , Stair , J , Fergus , S , Pezzolesi , C & Schifano , F 2020 , ' Novel psychoactive substances (NPS) – knowledge and experiences of drug users from Hungary, Poland, the UK and the USA ' , Neuropsychopharmacologia Hungarica , vol. 21 , no. 3 , pp. 152-163 . | |
dc.identifier.issn | 1419-8711 | |
dc.identifier.other | PURE: 17827973 | |
dc.identifier.other | PURE UUID: 5d3d85c0-3193-4530-b782-6f6a53d1dcd9 | |
dc.identifier.other | Scopus: 85072393129 | |
dc.identifier.other | ORCID: /0000-0002-7134-0665/work/70885847 | |
dc.identifier.other | ORCID: /0000-0001-7371-319X/work/98163899 | |
dc.identifier.uri | http://hdl.handle.net/2299/22450 | |
dc.description | Submitted 19 September 2019; Accepted 29 November 2019; Proof received 29 November 2019; Published 18 February 2020. Note: No DOI allocated. | |
dc.description.abstract | Dopamine D 3 receptor partial agonists represent a new generation of atypical antipsychotics. Cariprazine, which has received centralized market authorization from the European Medicines Agency in 2017 for the treatment of adult patients with schizophrenia (including those with predominant negative symptoms of schizophrenia) differs from the other two partial agonist antipsychotics aripiprazole and brexpiprazole due to its unique features. Cariprazine is a dopamine D 3 preferring D 3/D2 partial agonist with very similar dopamine receptor sub-type selectivity as dopamine. It has proven efficacy in the treatment of positive and negative symptoms of schizophrenia, as well as for relapse prevention. Further phase-3 clinical studies proved the efficacy of cariprazine in the acute treatment of manic or mixed episodes associated with bipolar I disorder, as well as in bipolar depression. For the adjunctive treatment of major depressive disorder, phase 3 studies are in progress. | en |
dc.format.extent | 11 | |
dc.language.iso | eng | |
dc.relation.ispartof | Neuropsychopharmacologia Hungarica | |
dc.rights | Open | |
dc.subject | novel psychoactive substances | |
dc.subject | drugs | |
dc.subject | addiction | |
dc.subject | delegalisation | |
dc.subject | international study | |
dc.subject | Predominant negative symptoms | |
dc.subject | Atypical antipsychotic | |
dc.subject | Cariprazine | |
dc.subject | Schizophrenia | |
dc.subject | Dopamine D and D receptor partial agonist | |
dc.subject | Clinical Neurology | |
dc.subject | Neuropsychology and Physiological Psychology | |
dc.subject | Neuroscience(all) | |
dc.subject | Pharmacology, Toxicology and Pharmaceutics(all) | |
dc.title | Novel psychoactive substances (NPS) – knowledge and experiences of drug users from Hungary, Poland, the UK and the USA | en |
dc.contributor.institution | Department of Clinical and Pharmaceutical Sciences | |
dc.contributor.institution | Centre for Clinical Practice, Safe Medicines and Drug Misuse Research | |
dc.contributor.institution | Centre for Health Services and Clinical Research | |
dc.contributor.institution | Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Unit | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
dc.description.status | Peer reviewed | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85072393129&partnerID=8YFLogxK | |
dc.identifier.url | http://mppt-nph.hu/images/magazin/pdf/vol21issue4/v21i4p152.pdf | |
dc.relation.school | School of Life and Medical Sciences | |
dc.description.versiontype | Final Published version | |
dcterms.dateAccepted | 2020-02-18 | |
rioxxterms.version | VoR | |
rioxxterms.licenseref.uri | Unspecified | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |
herts.rights.accesstype | Open | |