Show simple item record

dc.contributor.authorKim, Hyun Kuk
dc.contributor.authorTantry, Udaya S.
dc.contributor.authorPark, Hyun-Woong
dc.contributor.authorGeisler, Tobias
dc.contributor.authorGorog, Diana
dc.contributor.authorGurbel, Paul A
dc.contributor.authorJeong, Young-Hoon
dc.identifier.citationKim , H K , Tantry , U S , Park , H-W , Geisler , T , Gorog , D , Gurbel , P A & Jeong , Y-H 2021 , ' Ethnic Difference of Thrombogenicity in Patients with Cardiovascular Disease: A Pandora Box to Explain Prognostic Differences ' , Korean Circulation Journal , vol. 51 , no. 3 , pp. 202-221 .
dc.identifier.otherPURE: 24657451
dc.identifier.otherPURE UUID: 51a98285-1410-4117-82cf-f55768894124
dc.description© 2021. The Korean Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.description.abstractArterial and venous atherothrombotic events are finely regulated processes involving acomplex interplay between vulnerable blood, vulnerable vessel, and blood stasis.Vulnerable blood (‘thrombogenicity’) comprises complex interactions between cellularcomponents and plasma factors (inflammatory, procoagulant, anticoagulant, andfibrinolytic factors). The extent of thrombogenicity may determine the progression ofatheroma and the clinical manifestation of atherothrombotic events, with the highestthrombogenicity in African Americans and lowest in East Asians. Inherentthrombogenicity may influence clinical efficacy and safety of specific antithrombotictreatments in high-risk patients, which may in part explain the observation that EastAsians have reduced anti-ischemic benefits and elevated bleeding risk withantithrombotic therapy compared with Caucasians. In this review, we discuss availableevidence regarding the racial differences in thrombogenicity and its impact on clinicaloutcomes in patients with cardiovascular disease.en
dc.relation.ispartofKorean Circulation Journal
dc.titleEthnic Difference of Thrombogenicity in Patients with Cardiovascular Disease: A Pandora Box to Explain Prognostic Differencesen
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.description.statusPeer reviewed
rioxxterms.typeJournal Article/Review

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record