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        Psychonauts’ psychedelics: a systematic, multilingual, web-crawling exercise

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        Final Accepted Version (PDF, 831Kb)
        Author
        Catalani, Valeria
        Corkery, John Martin
        Guirguis, Amira
        Napoletano, Flavia
        Arillotta, Davide
        Zangani, Caroline
        Vento, Alessandro
        Schifano, Fabrizio
        Attention
        2299/24309
        Abstract
        Psychedelics alter the perception of reality through agonist or partial agonist interaction with the 2A serotoninergic receptor. They are classified as phenethylamines, tryptamines and lysergamides. These classes, according to the United Nations Office on Drugs and Crime (UNODC) and European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), account for an important percentage of the new psychoactive substances (NPS) current scenario. The paper aimed at: a) identifying and categorise psychedelic molecules from a list of psychonaut websites and NPS online resources; and b) comparing the NPSfinder® results with those from the European and United Nations databases. A crawling software (i.e. ‘NPSfinder®’) was created to automatically scan, 24/7, a list of URLs and to extract a range of information (chemical/street names, chemical formulae, etc.) to facilitate NPS identification. Data collected were manually analysed and compared with the EMCDDA and UNODC databases. The overall number of psychedelic NPS detected by NPSfinder® (November 2017-February 2020) was 1344, almost ten-times higher than that reported by the UNODC and EMCDDA combined. Of these, 994 previously unknown molecules were identified as (potential) novel psychedelics, suggesting a strong discrepancy between online and real-world NPS scenarios. The results show the interest of psychonauts, and maybe of the much larger community of ‘recreational’ drug users, towards psychedelics. Moreover, examining online scenarios may help in assessing the availability in the real world of psychedelic NPS; understanding drug trends; and in possibly predicting future drug scenarios.
        Publication date
        2021-08-01
        Published in
        European Neuropsychopharmacology
        Published version
        https://doi.org/10.1016/j.euroneuro.2021.03.006
        License
        http://creativecommons.org/licenses/by-nc-nd/4.0/
        Other links
        http://hdl.handle.net/2299/24309
        Relations
        School of Life and Medical Sciences
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