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Browsing University of Hertfordshire by Author "Chilcott, Robert"
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Non-invasive quantification of skin injury resulting from exposure to sulphur mustard and Lewisite vapours
Chilcott, Robert; Brown, Roger F. R.; Rice, P (2000-05)The severity and progression of skin lesions resulting from exposure to the chemical warfare agents Lewisite (L) and sulphur mustard (SM) have been investigated using the non-invasive biophysical methods of evaporimetry ... -
Octodrine: New Questions and Challenges in Sport Supplements
Catalani, Valeria; Prilutskaya, Mariya; Al-Imam, Ahmed; Marrinan, Shanna; Elgharably, Yasmine; Zloh, Mire; Martinotti, Giovanni; Chilcott, Robert; Corazza, Ornella (2018-02-20)Background: Octodrine is the trade name for Dimethylhexylamine (DMHA), a central nervous stimulant that increases the uptake of dopamine and noradrenaline. Originally developed as a nasal decongestant in the 1950’s, it has ... -
Optimisation of a dosing regime for a topical skin protectant (barrier cream)
Chilcott, Robert; Larner, Joanne; Matar, Hazem; Kansagra, Sneha; Theivendran, Baveetharan; Viegas, Vanessa Ann; Goldman, Virginia Streusand (2015)Context: Topical skin protectants (barrier creams) have the potential to reduce or enhance the severity of dermal lesions following exposure to allergens or irritants. Therefore, it is essential that such products are ... -
Optimisation of mass casualty decontamination procedures in vitro
Jones, David R.; Larner, Joanne; Price, Shirley C.; Chilcott, Robert (2010-12-30) -
Opto-thermal measurement of barrier cream residence time on skin in-vivo
Guo, X. X.; Ciortea, L. I.; Chilcott, Robert; Imhof, R. E.; Xiao, P. (2001)We report the non-invasive opto-thermal measurement of the residence time of a barrier cream on in-vivo skin. These measurements revealed an approximately exponential decrease of cream layer thickness with a 1/e disappearance ... -
The percutaneous toxicokinetics of sulphur mustard in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant
Hall, Charlotte; Lydon, Helen; Dalton, Christopher; Chipman, J. Kevin; Graham, John; Chilcott, Robert (2017-07-18)This study used a damaged skin, porcine model to evaluate the in vivo efficacy of WoundStat™ for decontamination of superficial (non-haemorrhaging), sulphur mustard-contaminated wounds. The dorsal skin of 12 female pigs ... -
Pharmacokinetics of acetylcholinesterase reactivator K203 and consequent evaluation of low molecular weight antioxidants/markers of oxidative stress
Karasová, J.Z.; Hnídková, D.; Pohanka, M.; Musílek, K.; Kuča, K.; Chilcott, Robert (2012)Oxime K203 is a new compound designed to be used as an acetylcholinesterase reactivator for the treatment of intoxication following exposure to tabun and certain pesticides. After intramuscular administration of a therapeutic ... -
Preliminary evaluation of military, commercial and novel skin decontamination products against a chemical warfare agent simulant (methyl salicylate)
Matar, Hazem; Guerreiro, Antonio; Piletsky, Sergey A.; Price, Shirley; Chilcott, Robert (2016-04-02)Rapid decontamination is vital to alleviate adverse health effects following dermal exposure to hazardous materials. There is an abundance of materials and products which can be utilised to remove hazardous materials from ... -
A preliminary study for assessing the feasibility of sebum sampling for monitoring human exposure to environmental chemicals following inadvertent or malicious release
Wakefield, James C.; Kaur, Kalwinder; Chilcott, Robert (2008-11-20) -
Profiling the vendors of COVID‐19 related product on the Darknet: An observational study
Catalani, Valeria; Townshend, Honor D.; Prilutskaya, Mariya; Roman-Urrestarazu, Andres; van Kessel, Robin; Chilcott, Robert; Banayoti, Hani; McSweeney, Tim; Corazza, Ornella (2023-04-05)BACKGROUND: In a time of unprecedented global change, the COVID-19 pandemic has led to a surge in demand of COVID-19 vaccines and related certifications. Mainly due to supply shortages, counterfeit vaccines, fake documentation, ... -
Protective effects of clothing on the in vitro absorption of chemical warfare agents
Matar, Hazem; Price, Shirley C.; Chilcott, Robert (2010-12-30) -
Recent advances to address European Union Health Security from cross border chemical health threats
Duarte-Davidson, R.; Orford, R.; Wyke, S.; Griffiths, M.; Amlôt, R.; Chilcott, Robert (2014-11)The European Union (EU) Decision (1082/2013/EU) on serious cross border threats to health was adopted by the European Parliament in November 2013, in recognition of the need to strengthen the capacity of Member States to ... -
Recent Changes in Drug Abuse Scenario: The Novel Psychoactive Substances (NPS) Phenomenon
Corazza, Ornella; Chilcott, Robert; Martinotti, Giovanni; Corkery, John; Guirguis, Amira; Zloh, Mire; Marrinan, Shanna; Catalani, Valeria (MDPI Multidisciplinary Digital Publishing Institute, 2019-01-01) -
SARS-CoV-2: characterisation and mitigation of risks associated with aerosol generating procedures in dental practices
Ehtezazi, Touraj; Evans, David G; Jenkinson, Ian D; Evans, Philip A; Vadgama, Vijay J; Vadgama, Jaimini; Jarad, Fadi; Grey, Nicholas; Chilcott, Robert (2021-01-07)Introduction: The objectives were to characterise the particle size distribution of aerosols generated by standard dental aerosol generating procedures (AGPs) and to assess the impact of aerosol-management interventions ... -
Sebomic identification of sex- and ethnicity-specific variations in residual skin surface components (RSSC) for bio-monitoring or forensic applications
Shetage, Satyajit; Traynor, Matthew; Brown, Marc; Chilcott, Robert (2018-08-21)Background: “Residual skin surface components” (RSSC) is the collective term used for the superficial layer of sebum, residue of sweat, small quantities of intercellular lipids and components of natural moisturising factor ... -
The skin reservoir of sulphur mustard
Hattersley, I. J.; Jenner, J.; Dalton, C.; Chilcott, Robert; Graham, J. S. (2008-09)Studies of the percutaneous reservoir of sulphur mustard (HD) formed during absorption carried out during WWI and WWII are inconclusive. More recent studies have indicated that a significant amount of HD remains in human ... -
Temporal effects of disrobing on the skin absorption of chemical warfare agents and CW agent simulants
Matar, Hazem; Price, Shirley C.; Chilcott, Robert (2010-12-30) -
Toxicity of sulphur mustard
Chilcott, Robert (2005-04-01) -
Transepidermal water loss does not correlate with skin barrier function in vitro
Chilcott, Robert; Dalton, C. H.; Emmanuel, A. J.; Allen, C. E.; Bradley, S. T. (2002-05)The purpose of this study was to investigate the relationship between transepidermal water loss and skin permeability to tritiated water ((H2O)-H-3) and the lipophilic penetrant sulfur mustard in vitro . No correlation was ... -
The United Kingdom’s initial operational response and specialist operational response to CBRN and HazMat incidents: a primer on decontamination protocols for healthcare professionals
Chilcott, Robert; Larner, Joanne; Matar, Hazem (2019-02-01)The UK is currently in the process of implementing a modified response to chemical, biological, radiological and nuclear and hazardous material incidents that combines an initial operational response with a revision of the ...