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Browsing University of Hertfordshire by Author "Sharma, Anand"
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Biomarkers in Bladder Cancer Surveillance
Sugeeta, Sukumar S.; Sharma, Anand; Ng, Kenrick; Nayak, Arvind; Vasdev, Nikhil (2021-09-28)Aim: This is a narrative review with an aim to summarise and describe urinary biomarkers in the surveillance of non-muscle-invasive bladder cancer (NMIBC). It provides a summary of FDA-approved protein biomarkers along ... -
Immunotherapy in Urological Tumors
Sharma, Anand; Suleyman, Narin M.; Vasdev, Nikhil; Jones, Oliver (2019)The past decade has seen significant improvement in our understanding of tumor biological features, which has led to use of anti-programmed-death 1 (PD-1) and anti-PDligand-1 (PD-L1) agents and cytotoxic T lymphocytes ... -
Incidental Lymphoplasmacytic Lymphoma Diagnosed Following Robotic-Assisted Laparoscopic Prostatectomy for Prostate Cancer
El-Taji, Omar; Omer, Altan; Al-Mitwalli, Abdullah; Agarwal, Samita; Sharma, Anand; Vasdev, Nikhil (2019-11-13)We report a case of prostatic lymphoma of the Walden-ström's macroglobulinemia subtype in a 64-year-old gentleman who underwent a robotic-assisted laparoscopic prostatectomy following lower urinary tract symptoms and high ... -
The increasing indications of FDG-PET/CT in the staging and management of Invasive Bladder Cancer
Omorphos, Nicolas Pavlos; Ghose, Aruni; Hayes, John; Kandala, Abhinav; Dasgupta, Prokar; Sharma, Anand; Vasdev, Nikhil (2022-10-30)The management of locally advanced muscle invasive bladder cancer (MIBC) often necessitates neo-adjuvant chemotherapy (NAC) to eliminate any micro-metastatic disease prior to definitive radical cystectomy (RC) and pelvic ... -
A North-West London Experience of the Impact of Treatment Related Toxicity on Clinical Outcomes of Elderly Patients with Germ Cell Tumors
Sharma, Anand; Morrison, Laura; Milic, Marina; Ghose, Aruni; Gogbashian, Andrew; Vasdev, Nikhil; Agarwal, Samita; Pullar, Ben; Rustin, Gordon (2022-10-11)Simple Summary: Germ cell testicular cancer is seen in men aged 15–35. Incidence of this cancer in the elderly aged > 45 is less than 10%. The aim of our retrospective study is to understand the treatment-related toxicity ... -
Outcomes of the 2019 Novel Coronavirus in patients with or without a history of cancer - a multi-centre North London experience
Joharatnam, Nalinie; Hochhauser, Daniel; Shiu, Kai-Keen; Crolley, Valerie; Rush, Hannah; Wilson, William; Sharma, Anand; Vasdev, Nikhil; Anwar, Muhammad; Kantser, Ganna; Raja, Fharat; Bridgewater, John; Khan, Khurum (2020-09-14)Background Four months after the first known case of the 2019 novel coronavirus disease (COVID-19), on the 11th March 2020, the WHO declared the outbreak a pandemic and acknowledged the potential to overwhelm national ... -
Role of perioperative immune checkpoint inhibitors in muscle invasive bladder cancer
Chhaya, Saachi; Watts, Isabella; Ng, Kenrick; Mustapha, Rami; Powles, Thomas; Sharma, Anand; Vasdev, Nikhil (2023-01-03)Objective To describe and highlight the current use of immune checkpoint inhibitors (ICIs) in the muscle-invasive bladder cancer (MIBC) treatment landscape, particularly focusing on the perioperative setting. We provide a ... -
Secondary Neoplasms of the Urinary Bladder-Clinical Management and Oncological Outcomes
El-Taji, Omar; Al-Mitwalli, Abdullah; Malik, Farhan; Agarwal, Samita; Gogbashian, Andrew; Hughes, Rob; Vasdev, Nikhil; Sharma, Anand (2021-06-01)Background: Secondary neoplasms of the bladder account for 4.5% of all bladder neoplasms however there is limited literature reporting management and survival. This is the largest single centre series presented in current ... -
Survival Outcomes After High-dose Chemotherapy and Stem Cell Transplantation in the Salvage Setting for Relapsed or Refractory Germ Cell Cancers
Sharma, Anand; Babra, Deshveer; Joshi, Priya; Hall, Marcia; Gogbashian, Andrew; Vasdev, Nikhil; Joseph, Magdalene; Yazdan, Amir; Kanfer, Edward (2020-11)Background/Aim: High-dose chemotherapy (HDCT) and stem cell transplantation (SCT) have been established as the standard of care in patients with relapsed germ cell tumours (GCTs). We evaluated the safety, efficacy and ... -
Urinary biomarkers in bladder cancer: A review of the current landscape and future directions
Ng, Kenrick; Stenzl, Arnulf; Sharma, Anand; Vasdev, Nikhil (2021-01-01)This narrative review aims to describe established and emerging urinary biomarkers in the diagnosis and surveillance of non-muscle invasive bladder cancer (NMIBC). It provides a comprehensive account of classical, FDA-approved ... -
Urinary Biomarkers: Mitigating Diagnostic Delays of Bladder Cancer in the COVID-19 era
Ng, Kenrick; Vinnakota, Krishna; Sharma, Anand; Cresswell, Joanne; Kelly, John; Dasgupta, Prokar; Vasdev, Nikhil (2020-12-17)The COVID-19 pandemic has resulted in a substantial increase in waiting times for cystoscopies, prompting concerns of delayed diagnoses and substandard surveillance of bladder cancer. Expanding the role of urinary biomarkers ...