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Browsing University of Hertfordshire by Author "Stair, Jacqueline L."
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Elemental fingerprinting of Hypericum perforatum (St John's Wort) herb and preparations using ICP-OES and chemometrics
Owen, Jade D.; Kirton, Stewart B.; Evans, Sara J.; Stair, Jacqueline L. (2016-06-05)St. John's wort (SJW) (Hypericum perforatum) is a herbal remedy commonly used to treat mild depression. The elemental profiles of 54 samples (i.e., dry herbs, tablets and capsules) were evaluated by monitoring 25 elements ... -
Elemental Profile of Hypericum perforatum (St John's Wort) Preparations Using Icp-Oes
Owen, Jade D.; Evans, Sara J.; Stair, Jacqueline L. (2010-10) -
Flipped detection of psychoactive substances in complex mixtures using handheld Raman spectroscopy coupled to chemometrics
Calvo‐Castro, Jesus; Tchakounte, Steve N.; Guarino, Valentina; Ahmed, Adeel A.; Stair, Jacqueline L. (2022-05-23)New psychoactive substance (NPS) misuse represents a critical social and health problem. Herein, a novel flipped approach is presented for the detection of psychoactive substances in complex mixtures using portable Raman ... -
Metal binding characterization and conformational studies using Raman microscopy of resin-bound poly(aspartic acid)
Stair, Jacqueline L.; Holcombe, James A. (2007-03-01)The metal binding capacities, conditional stability constants, and secondary structure of immobilized polyaspartic acid (PLAsp) (n = 6, 20, and 30) on TentaGel resin were determined when binding Mg2+, Co2+, Cd2+, and Ni2+. ... -
A molecular dynamic investigation of viscosity and diffusion coefficient of nanoclusters in hydrocarbon fluids
Loya, Adil; Stair, Jacqueline L.; Jafri, Ali R.; Yang, Ke; Ren, Guogang (2015-03)Straight chain alkanes modified by metal oxide nanoclusters have gained wide recognition in applications in tribology, energy and thermal storage. This paper investigates the system’s rheological properties and diffusion ... -
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids : BB-22, 5F-PB-22, 5F-AKB-48 and STS-135
De Luca, Maria Antonietta; Castelli, M. Paola; Loi, Barbara; Porcu, Alessandra; Martorelli, Mariella; Miliano, Cristina; Kellett, Kathryn; Davidson, Colin; Stair, Jacqueline L.; Schifano, Fabrizio; Di Chiara, Gaetano (2016-06-01)In order to investigate the in vivo dopamine (DA) stimulant properties of selected 3rd generation Spice/K2 cannabinoids, BB-22, 5F-PB-22, 5F-AKB-48 and STS-135, their in vitro affinity and agonist potency at native rat and ... -
Quantitative determination of single-bead metal content from a peptide combinatorial library
Stair, Jacqueline L.; White, Brianna R.; Rowland, Adam; Holcombe, James A. (2006-11-13)An electrothermal vaporizer inductively coupled plasma mass spectrometer (ETV-ICPMS) was used to quantitatively screen metals bound to single polystyrene (TentaGel) beads with immobilized oligopeptides. Tests were performed ... -
Sensor materials for the detection of proteases
Stair, Jacqueline L.; Watkinson, Michael; Krause, Steffi (2009-03-15)The concept of generic and tunable sensor materials for the detection of proteases based on the thin film degradation of peptide cross-linked dextran hydrogels was explored. Hydrogel cross-links were formed via simple imine ... -
Small molecule recognition of mephedrone using an anthracene molecular clip
Kellett, Kathryn; Broome, J. Hugh; Zloh, Mire; Kirton, Stewart B.; Fergus, Suzanne; Gerhard, Ute; Stair, Jacqueline L.; Wallace, Karl J. (2016-05-16)An anthracene molecular probe has been synthesised and shown to target mephedrone, a stimulant drug from the cathinone class of new psychoactive substances (NPS). A protocol has been developed to detect mephedrone via the ...