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Browsing University of Hertfordshire by Author "Yu, Yang"
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Ageing and gastrointestinal sensory function: altered colonic mechanosensory and chemosensory function in the aged mouse.
Keating, Christopher; Nochi, Linda; Yu, Yang; Donovan, Jemma; Grundy, D (2016-08-14)Ageing has a profound effect upon gastrointestinal function through mechanisms that are poorly understood. Here we investigated the effect of age upon gastrointestinal sensory signalling pathways in order to address the ... -
Deoxycholic acid activates colonic afferent nerves via 5-HT3 receptor dependent and independent mechanisms
Yu, Yang; Villalobos- Hernandez, Egina; Pradhananga, Sabindra; Baker, Corey; Keating, Christopher; Grundy, David; Lomax, Allan; Reed, David (2019-09-01)Increased bile acids in the colon can evoke increased epithelial secretion resulting in diarrhea, but little is known about whether colonic bile acids contribute to abdominal pain. This study aimed to investigate the ...