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Developing microfluidic devices and techniques for isolation and detection of Extracellular Vesicles (EVs)
(2020-10-09)
The purpose of this research is to develop microfluidic devices and systems for the effective isolation of bacterial Extracellular vesicles (EVs) by applying Tangential Flow Filtration (TFF) operation. The purification and ...
Human skeletal muscle derived microvesicles induce apoptosis in highly metastatic prostate cancer cells
(2012-09-13)
The human skeletal muscle is a highly vascularised tissue that contributes approximately 40% of the total body mass. These two factors make it a prime target for secondary cancer metastases. Surprisingly, malignant cancers ...
Cancer cell expulsion of anticancer drugs through shedding of microvesicles: association with drug resistance and tumour survival
(2012-09-13)
Microvesicles (MVs) are small (0.1-≤1 µm in diameter) heterogeneous vesicles released from cells constitutively or upon activation, that mediate intercellular communication. Multi-drug resistance (MDR) has been defined as ...