Browsing Research publications by Author "Extracellular Vesicle Research Unit"
Now showing items 21-40 of 151
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A comparison of urology training across five major english-speaking countries
Naik, Rishi; Mandal, Indrajeet; Hampson, Alexander; Casey, Rowan; Vasdev, Nikhil (2020-03-20)Background: Urology is a rapidly evolving specialty, although wide variations exist between training programs in different countries. We aimed to compare the status of urology training in 5 English-speaking countries. ... -
Concurrent growth rate and transcript analyses reveal essential gene stringency in Escherichia coli
Goh, Shan; Boberek, Jaroslaw M; Nakashima, Nobutaka; Stach, Jem; Good, Liam (2009-06-26)BACKGROUND: Genes essential for bacterial growth are of particular scientific interest. Many putative essential genes have been identified or predicted in several species, however, little is known about gene expression ... -
Continuously variable mixing-ratio micromixer with elastomer valves
Tan, C. K. L.; Tracey, M.C.; Davis, J. B.; Johnston, I. D. (2005-10)We report a self-contained microfluidic alternate flow injection mixer (AFIM) employing piezoelectrically actuated, PDMS seal-valves to control injection. AFIMs employ pulsatile injection of liquids to enhance interface ... -
Control of arable crop pathogens; climate change mitigation, impacts and adaptation
Fitt, Bruce; Stotz, Henrik; Hughes, David (Springer Nature, 2016-03-29)In the context of threats to global food security from impacts of damaging crop diseases and of climate change, this chapter describes three aspects of the interactions between climate change and diseases that reduce arable ... -
Controlled Actuation of Self-Propelled Droplets
Coudron, Loic; Lemenu, Clément; Lemaine, Kevin; McCluskey, Daniel; Tan, Christabel; Munro, Ian; Holdo, Arne; Tracey, Mark; Johnston, Ian (2020-10-09)In this paper we present controlled self-propelled actuation of droplets employing Laplace pressure gradients between two non-parallel superhydrophobic plates. For small angles (cos β ≈ 1) a simplification of available ... -
Current Practices and the Future of Robotic Surgical Training
Sinha, Ankit; West, Alexander; Vasdev, Nikhil; Sooriakumaran, Prasanna; Rane, Abhay; Dasgupta, Prokar; McKirdy, Michael (2023-03-15)Introduction: This study reviews the current state of robotic surgery training for surgeons, including the various curricula, training methods, and tools available, as well as the challenges and limitations of these. ... -
Current role of cytoreductive nephrectomy in metastatic renal cell carcinoma
Van Praet, Charles; Slots, Charlotte; Vasdev, Nikhil; Rottey, Sylvie; Fonteyne, Valérie; Andras, Iulia; Albersen, Maarten; De Meerleer, Gert; Bex, Axel; Decaestecker, Karel (2021-02-01)Historically, immediate cytoreductive nephrectomy (CN) was considered the standard of care in patients with metastatic renal cell carcinoma (mRCC) who were fit enough to undergo surgery. Recently, 2 randomized controlled ... -
Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic
STARSurg Collaborative; COVIDSurg Collaborative (2021-11-13)Background: This study aimed to determine the impact of pulmonary complications on death after surgery both before and during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Methods: This was a ... -
Decreased function of survival motor neuron protein impairs endocytic pathways
Dimitriadi, Maria; Derdowski, Aaron; Kalloo, Geetika; Maginnis, Melissa S; O'Hern, Patrick; Bliska, Bryn; Sorkaç, Altar; Nguyen, Ken C Q; Cook, Steven J; Poulogiannis, George; Atwood, Walter J; Hall, David H; Hart, Anne C (2016-07-26)Spinal muscular atrophy (SMA) is caused by depletion of the ubiquitously expressed survival motor neuron (SMN) protein, with 1 in 40 Caucasians being heterozygous for a disease allele. SMN is critical for the assembly of ... -
Delayed radical prostatectomy for localised prostate cancer – A systematic review and meta-analysis for the COVID-19 Pandemic
Chan, Vinson Wai-Shun; Tan, Wei Shen; Asif, Aqua; Ng, Alexander; Gbolahan, Olayinka; Dinneen, Eion; To, Wilson; Kadhim, Hassan; Premchand, Melissa; Burton, Oliver; Koe, Jasmine Sze-Ern; Wang, Nicole; Leow, Jeffrey; Giannarini, Gianluca; Vasdev, Nikhil; Shariat, S. F.; Enikeev, Dmitry; Ng, Chi Fai; Teoh, Jeremy (2021-06-30)External factors, such as the coronavirus disease 2019 (COVID-19), can lead to cancellations and backlogs of cancer surgeries. The effects of these delays are unclear. This study summarised the evidence surrounding expectant ... -
Design of a high efficiency cyclone for collection of rare and low concentration airborne pathogens
Baxter, Richard; Johnston, Ian; Kaye, Richard; Munro, Ian; Tracey, Mark; Day, Rodney; McCluskey, Daniel (2017-03-16)Recent serious outbreaks of pathogens such as Chalara Fraxinea, (Ash Dieback) demonstrate the vulnerability of UK’s forests, woods, and trees. Early detection of threats is critical in the fight against such tree pests and ... -
Detection rates of recurrent prostate cancer : 68Gallium (Ga)-labelled prostate-specific membrane antigen versus choline PET/CT scans. A systematic review
Moghul, Masood; Somani, Bhaskar; Lane, Tim; Vasdev, Nikhil; Chaplin, Brian; Peedell, Clive; KandaSwamy, Gokul Vignesh; Rai, Bhavan Prasad (2019-01-24)Background: The aim of this work was to assess the use of prostate-specific membrane antigen (PSMA)-labelled radiotracers in detecting the recurrence of prostate cancer. PSMA is thought to have higher detection rates when ... -
Developing microfluidic devices and techniques for isolation and detection of Extracellular Vesicles (EVs)
Lekkala, Himayasri; Dimov, Nikolay; Johnston, Ian; Inal, Jameel (2020-10-09)The purpose of this research is to develop microfluidic devices and systems for the effective isolation of bacterial Extracellular vesicles (EVs) by applying Tangential Flow Filtration (TFF) operation. The purification and ... -
Developing microfluidic platforms for rapid identification of new targets for neurodegenerative disorders
Pacheco Torres, Paloma; Kaye, Richard; Johnston, Ian; Dimitriadi, Maria; Tan, Christabel (2023-10-19) -
Development of a Potential Yeast-Based Vaccine Platform for Theileria parva Infection in Cattle
Goh, Shan; Kolakowski, Jeannine; Holder, Angela; Pfuhl, Mark; Ngugi, Daniel; Ballingall, Keith; Tombacz, Kata; Werling, Dirk (2021-07-08)East Coast Fever (ECF), caused by the tick-borne apicomplexan parasite Theileria parva, remains one of the most important livestock diseases in sub-Saharan Africa with more than 1 million cattle dying from infection every ... -
Development of an automated smart trap for wheat pathogens
Kaye, Richard; Johnston, Ian; Baxter, Richard; Munro, Ian; Tracey, Mark; Day, Rodney; McCluskey, Daniel (2017-03-16)National surveys show fungicide use on wheat continues to increase despite fluctuations in disease pressure, reaching a 30 year high in 2012 (Defra). Septoria tritici is the most significant foliar disease in UK wheat ... -
The development of species-specific antisense peptide nucleic acid method for the treatment and detection of viable Salmonella
Adebowale, Oluwawemimo; Goh, Shan; Good, Liam (2020-06)Genotypic based detection methods using specific target sites in the pathogen genome can complement phenotypic identification. We report the development of species-specific antisense peptide nucleic acid (PNA) combined ... -
Dielectrophoretic collection of airborne particles
Chung, Etelka; Heidari Koochi, Milad; Weerasiri, Lanka; Munro, Ian; Johnston, Ian; Chrysanthou, Andreas; Coudron, Loic (2024-06-06)Aim: To investigate dielectrophoresis as a mechanism for collection of bioaerosols. -
Digital process control of multi-step assays on centrifugal platforms using high-low-high rotational-pulse triggered valving
Early, Philip L.; Kilcawley, Niamh A.; McArdle, Niamh A.; Renou, Marine; Kearney, Sinéad M.; Mishra, Rohit; Dimov, Nikolay; Glynn, Macdara T.; Ducrée, Jens; Kinahan, David J. (2023-09-08)Due to their capability for comprehensive sample-to-answer automation, the interest in centrifugal microfluidic systems has greatly increased in industry and academia over the last quarter century. The main applications ... -
Disease management in oilseed rape: insights into the Brassica napus-Pyrenopeziza brassicae pathosystem
Karandeni Dewage, Chinthani Shanika; Qi, Aiming; Stotz, Henrik; Huang, Yongju; Fitt, Bruce (AFCP, 2021-06-16)