Browsing Research publications by Author "Public Health and Patient Safety Unit"
Now showing items 1-20 of 96
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5,6-Methylenedioxy-2-aminoindane : from laboratory curiosity to 'legal high'
Gallagher, C. T.; Assi, S.; Stair, J. L.; Fergus, S.; Corazza, Ornella; Corkery, John; Schifano, Fabrizio (2012-03-01)The fully synthetic 'legal high' 5,6-methylenedioxy-2-aminoindane (MDAI) is an analogue of 3,4-methylenedioxymethamphetamine. Although developed in the 1990s, it was not widely abused until 2010. However, mephedrone was ... -
Antibiotic Prescribing: A Retrospective Study from One English National Health Service (NHS) Foundation Trusts Before And During The COVID-19 Pandemic.
Abdelsalam Elshenawy, Rasha; Umaru, Nikkie; Aslanpour, Zoe (2023-06-20)This research by Abdelsalam Elshenawy Rasha., investigates antibiotic prescribing practices before and during the COVID-19 pandemic at an English NHS Trust. It focuses on understanding the implications of Antimicrobial ... -
Antimicrobial stewardship implementation before and during the COVID-19 pandemic in the acute care settings: a systematic review
Elshenawy, Rasha Abdelsalam; Umaru, Nkiruka; Alharbi, Amal Bandar; Aslanpour, Zoe (2023-02-10)Introduction: Antibiotics are widely administered for various indications, leading to increased antimicrobial resistance (AMR) in acute care hospitals. Since the onset of the COVID-19 pandemic, Antimicrobial Stewardship ... -
Antimicrobial Stewardship Intervention During The COVID-19 Pandemic in the Acute Settings: A Systematic Literature Review
Abdelsalam Elshenawy, Rasha; Umaru, Nikkie; Alharbi, Amal Bandar; Aslanpour, Zoe (Research Square Preprints, 2022-08-28)This systematic review investigates Antimicrobial Stewardship (AMS) interventions before (PP) and during the COVID-19 pandemic (DP) in acute care settings. The review synthesises evidence from 16 primary studies published ... -
Antimicrobial Stewardship Program Implementation in a Saudi Medical City: An Exploratory Case Study.
Alghamdi, Saleh; Berrou, Ilhem; Aslanpour, Zoe; Bajnaid, Eshtyag; Hammad, Mohamed; Haseeb, Abdul; Shebl, Nada Atef (2021-03-09)Antimicrobial stewardship programs (ASPs) in hospitals have long been shown to improve antimicrobials’ use and reduce the rates of antimicrobial resistance. However, their implementation in hospitals, especially in developing ... -
Antimicrobial Stewardship Strategies, Measures and Quality Improvement During COVID-19: The Role of Pharmacist
Abdelsalam Elshenawy, Rasha; Umaru, Nikkie; Aslanpour, Zoe (2021-11-10)This research delves into Antimicrobial Stewardship (AMS) strategies and quality improvement measures in acute-care hospitals during the COVID-19 pandemic, with a focus on the role of pharmacists. It examines how the ... -
Antimicrobial Stewardship: Shorter and Longer Courses of Antibiotics in Respiratory Tract Infection Before and During the COVID-19 Pandemic at one English Foundation Trust.
Abdelsalam Elshenawy, Rasha; Umaru, Nikkie; Aslanpour, Zoe (2023-09-14)This study reveals that shorter duration of antibiotics demonstrates the same appropriateness for infections like CAP, HAP, and COPD as per local antimicrobial guidelines. Conversely, longer antibiotic durations didn't ... -
Appraisal of patient-reported outcome measures in analogous diseases and recommendations for use in phase II and III clinical trials of pyruvate kinase deficiency
Salek, Mir-Saeed Shayegan; Ionova, Tatyana; Johns, Jeffrey; Oliva, Esther Natalie (2018-11-19)Purpose: Pyruvate kinase deficiency (PKD) is a rare disease and understanding of its epidemiology and associated burden remains limited. With no current curative therapy, clinical manifestations can be life threatening, ... -
Appropriate and inappropriate influences on outpatient discharge decision making in dermatology : a prospective qualitative study
Harun, N A; Finlay, A Y; Salek, M S; Piguet, V (2015-09-01)BACKGROUND: Outpatient discharge decision making in dermatology is poorly understood. OBJECTIVE: To identify the influences on clinicians' thought processes when making discharge decisions in dermatology outpatient clinics. ... -
Assessing the integration of pharmacist independent prescribers in child and adolescent mental health services
Shah, Chetan; Umaru, Nkiruka; Adams, Eleanor; Johal, Mandeep; Faridi, Arshad; Kah, Mirza; Zia, Asif; Magon, Rakesh (2021-04-01)Introduction: Owing to high demand and staff recruitment challenges, child and adolescent mental health services (CAMHS) in England have struggled to meet expectations set by the NHS and Royal College of Psychiatrists ... -
ATM automation: guidance on human technology integration
Amaldi, Paola; Quercioli, Monica (CAA UK, 2016-03-01)Human interaction with technology and automation is a key area of interest to industry and safety regulators alike. In February 2014, a joint CAA/industry workshop considered perspectives on present and future implementation ... -
Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study
Alghamdi, Saleh; Shebl, Nada; Aslanpour, Zoe; Berrou, Ilhem (2019-09-01)Objectives: This study explored antimicrobial stewardship programme (ASP) team members’ perspectives regarding factors influencing the adoption and implementation of these programmes in Saudi hospitals. Methods: This was ... -
Behaviour Change Strategies to Influence Antimicrobial Stewardship During COVID-19 Pandemic in acute care settings.
Abdelsalam Elshenawy, Rasha; Umaru, Nikkie; Aslanpour, Zoe (2021-06-22)This research explores the effectiveness of Antimicrobial Stewardship (AMS) interventions, focusing on behavioural change strategies during the COVID-19 pandemic in acute care settings. Employing a systematic literature ... -
The Burden of Disease in Pyruvate Kinase Deficiency: Patients' Perception of the Impact on Health-Related Quality of Life
Grace, RF; Cohen, L; Egan, S; Wells, T; Witherspoon, B; Ryan, A; Salek, Mir-Saeed Shayegan; Bodie, S; Klaassen, RJ (2018-12-01)Objectives: This study explored how signs and symptoms of pyruvate kinase (PK) deficiency, a rare hemolytic anemia caused by mutations in the PKLR gene, impacts patients’ health-related quality of life (HRQoL). Methods: ... -
Conflicting regulations on medicines and controlled drugs may expose pharmacists to criminal liability
Gallagher, Cathal (2021-03-29) -
Correlating the Dermatology Life Quality Index with psychiatric measures: A systematic review.
Ali, FM; Johns, Nutjaree; Salek, Mir-Saeed Shayegan; Finlay, Andrew Y. (2018-11-01)Skin conditions may have a major impact on the psychologic well-being of patients, ranging from depression to anxiety. The Dermatology Life Quality Index (DLQI) is the most commonly used quality of life tool in dermatology, ... -
Determinants of Psychosocial Health in Psoriatic Patients: A Multinational Study
Lesner, Karolina; Reich, Adam; Szepietowski , Jacek C; Dalgard, Florence; Finlay, Andrew Y.; Kupfer, Joerg; Gieler, Uwe; Salek, Mir-Saeed Shayegan (2017-11-01)There are limited data on the differences in the impact of psoriasis between various countries with respect to quality of life (QoL). The aim of this study was to explore the psychosocial health of patients with psoriasis ... -
The Development and Validation of a Generic Instrument, QoDoS, for Assessing the Quality of Decision Making.
Donelan, R; Walker, Stuart; Salek, Mir-Saeed Shayegan (2016-07-13)Introduction: The impact of decision-making during the development and the regulatory review of medicines greatly influences the delivery of new medicinal products. Currently, there is no generic instrument that can be ... -
Development of a Consumer Reported Outcome Measure for Personal Care Products : The Rationale
Falcone, Robert; Umaru, Nikkie; michniak-kohn, Bozena; Salek, Sam (2024-01-30)Background: Cosmetic products are one of the fastest-growing segments of personal care products in the United States. One of the critical elements in the sales and growth of cosmetics is leveraging claims. Unlike pharmaceuticals ... -
Development of a Novel Hematological Malignancy Specific Patient-Reported Outcome Measure (HM-PRO) : Content Validity
Goswami, Pushpendra; Oliva, Esther; Ionova, Tatyana; Else, R; Kell, J; Fielding, AK; Jennings, DM; Karakantza , M; Al-Ismail, S; Collins, GP; McConnell , S; Langton, Catherine; Salek, Sam (2020-03-05)Background: The quality of life of patients at all stages of hematological malignancy is greatly affected by the disease and its treatment. There is a wide range of health-related quality of life (HRQoL) issues important ...