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Cloning and functional expression of a human orthologue of the rat vanilloid receptor-1
(2000-11-01)
Capsaicin, resiniferatoxin, protons or heat have been shown to activate an ion channel, termed the rat vanilloid receptor-1 (rVR1), originally isolated by expression cloning for a capsaicin sensitive phenotype. Here we ...
Cloning, localisation and functional expression of the human ortholgue of the TREK-1 potassium channel
(2000)
We have cloned human TREK-1, one of the newly emerging mammalian family of 2-P domain potassium channels. The channel has 411 amino acids with a 41-amino-acid extension at the C-terminus when compared with the cloned mouse ...