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Now showing items 11-17 of 17
Bio-logic: gene expression and the laws of combinatorial logic
(2008)
At the heart of the development of fertilized eggs into fully formed organisms and the adaptation of cells to changed conditions are genetic regulatory networks (GRNs). In higher multi-cellular organisms, signal selection ...
Automatic Analysis of Computation in BioChemical Reactions
(2008)
We propose a modeling and analysis method for biochemical reactions based on finite state automata. This is a completely different approach compared to traditional modeling of reactions by differential equations. Our method ...
Genetic regulatory network models of biological clocks : evolutionary history matters
(2008)
We study the evolvability and dynamics of artificial genetic regulatory networks (GRNs), as active control systems, realizing simple models of biological clocks that have evolved to respond to periodic environmental stimuli ...
The Essential Motif that wasn't there: Topological and Lesioning Analysis of Evolved Genetic Regulatory Networks
(Institute of Electrical and Electronics Engineers (IEEE), 2007)
Evolving biological clocks using genetic regulatory networks
(MIT Press, 2006)
Evolutionary robustness of differentiation in genetic regulatory networks
(IOS Press, 2006)
We investigate the ability of artificial Genetic Regulatory Networks (GRNs) to evolve differentiation. The proposed GRN model supports non-linear interaction between regulating factors, thereby facilitating the realization ...