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Now showing items 851-860 of 952
Etidronate rescues cognitive deficits through improving synaptic transmission and suppressing apoptosis in 2-vessel occlusion model rats
(2017-01-20)
Vascular dementia (VD) is a neurodegenerative disorder caused by the reduction of cerebral blood flow. It shows a progressive cognitive impairment. In our previous study, we found that etidronate (ET) showed neuroprotective ...
Studies on the Detection, Expression, Glycosylation, Dimerization, and Ligand Binding Properties of Mouse Siglec-E
(2017-01-20)
CD33-related Siglecs are a family of proteins widely expressed on innate immune cells. Binding of sialylated glycans or other ligands triggers signals that inhibit or activate inflammation. Immunomodulation by Siglecs has ...
ALMA Observations of the Water Fountain Pre-Planetary Nebula IRAS 16342-3814: High-velocity bipolar jets and an Expanding Torus
(2017-01-20)
We have mapped 12CO J=3–2 and other molecular lines from the “water fountain” bipolar pre-planetary nebula (PPN) IRAS 16342-3814 with ∼0.35″ resolution using Atacama Large Millimeter/submillimeter Array. We find (i) two ...
Development report EnviGuard Port physical components (D5.4)
(Technologie-Transfer-Zentrum Bremerhaven, 2017-01-19)
Patient reported outcome measures in child and adolescent mental health services: Associations between clinician demographic characteristics, attitudes, and efficacy
(2017-01-19)
Background Policy recommends using patient reported outcome measures (PROMs), yet their use is persistently low. Our aim was to examine the association between PROM use and clinician demographic characteristics, attitudes ...
Adherence to prophylaxis in adolescents and young adults with severe haemophilia: A quantitative study with patients
(2017-01-19)
Introduction: haemophilia is an inherited bleeding disorder caused by a deficiency in one of the blood coagulation factors. For people affected by severe haemophilia, the deficiency can cause spontaneous internal bleeding. ...
A Discrete Event Simulation model to evaluate the use of community services in the treatment of patients with Parkinson’s disease in the United Kingdom.
(2017-01-18)
Background: The number of people affected by Parkinson’s disease (PD) is increasing in the United Kingdom driven by population ageing. The treatment of the disease is complex, resource intensive and currently there is no ...
The 4C framework for making reasonable adjustments for people with learning disabilities
(2017-01-18)
Background People with learning disabilities experience significant inequalities in accessing healthcare. Legal frameworks, such as the Equality Act 2010, are intended to reduce such disparities in care, and require ...
An analytical model for the identification of the threshold of stress intensity factor range for crack growth
(2017-01-18)
The value of the stress intensity factor (SIF) range threshold (∆K_th ) for fatigue crack growth (FCG) depends highly on its experimental identification. The identification and application of ∆K_(th )are not well established ...
Delivering a Brighter Future for IT Projects
(2017-01-17)