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The increasing indications of FDG-PET/CT in the staging and management of Invasive Bladder Cancer
(2022-10-30)
The management of locally advanced muscle invasive bladder cancer (MIBC) often necessitates neo-adjuvant chemotherapy (NAC) to eliminate any micro-metastatic disease prior to definitive radical cystectomy (RC) and pelvic ...
A North-West London Experience of the Impact of Treatment Related Toxicity on Clinical Outcomes of Elderly Patients with Germ Cell Tumors
(2022-10-11)
Simple Summary: Germ cell testicular cancer is seen in men aged 15–35. Incidence of this cancer in the elderly aged > 45 is less than 10%. The aim of our retrospective study is to understand the treatment-related toxicity ...
Biomarkers in Bladder Cancer Surveillance
(2021-09-28)
Aim: This is a narrative review with an aim to summarise and describe urinary biomarkers in the surveillance of non-muscle-invasive bladder cancer (NMIBC). It provides a summary of FDA-approved protein biomarkers along ...
Secondary Neoplasms of the Urinary Bladder-Clinical Management and Oncological Outcomes
(2021-06-01)
Background: Secondary neoplasms of the bladder account for 4.5% of all bladder neoplasms however there is limited literature reporting management and survival. This is the largest single centre series presented in current ...
Urinary biomarkers in bladder cancer: A review of the current landscape and future directions
(2021-01-01)
This narrative review aims to describe established and emerging urinary biomarkers in the diagnosis and surveillance of non-muscle invasive bladder cancer (NMIBC). It provides a comprehensive account of classical, FDA-approved ...
Urinary Biomarkers: Mitigating Diagnostic Delays of Bladder Cancer in the COVID-19 era
(2020-12-17)
The COVID-19 pandemic has resulted in a substantial increase in waiting times for cystoscopies, prompting concerns of delayed diagnoses and substandard surveillance of bladder cancer. Expanding the role of urinary biomarkers ...
Survival Outcomes After High-dose Chemotherapy and Stem Cell Transplantation in the Salvage Setting for Relapsed or Refractory Germ Cell Cancers
(2020-11)
Background/Aim: High-dose chemotherapy (HDCT) and stem cell transplantation (SCT) have been established as the standard of care in patients with relapsed germ cell tumours (GCTs). We evaluated the safety, efficacy and ...
Outcomes of the 2019 Novel Coronavirus in patients with or without a history of cancer - a multi-centre North London experience
(2020-09-14)
Background Four months after the first known case of the 2019 novel coronavirus disease (COVID-19), on the 11th March 2020, the WHO declared the outbreak a pandemic and acknowledged the potential to overwhelm national ...