Emergence of reduced susceptibility to metronidazole in Clostridium difficile

Baines, Simon D.; O'Connor, Rachael; Freeman, Jane; Fawley, Warren N; Harmanus, Celine; Mastrantonio, Paola; Kuijper, Ed J.; Wilcox, M. H.

Emergence of reduced susceptibility to metronidazole in Clostridium difficile

Baines, Simon D., O'Connor, Rachael, Freeman, Jane, Fawley, Warren N, Harmanus, Celine, Mastrantonio, Paola, Kuijper, Ed J. and Wilcox, M. H. (2008) Emergence of reduced susceptibility to metronidazole in Clostridium difficile. Journal of Antimicrobial Chemotherapy, 62 (5). pp. 1046-52. ISSN 1460-2091

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Antimicrobial treatment for Clostridium difficile infection (CDI) has typically been metronidazole, although reports have questioned the efficacy of this option. We screened recently isolated C. difficile (2005-06) for susceptibility to metronidazole and compared results for historic isolates (1995-2001).

Item Type	Article
Identification Number	10.1093/jac/dkn313
Date Deposited	15 May 2025 12:33
Last Modified	04 Oct 2026 00:56

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Baines, Simon D.

Journal of Antimicrobial Chemotherapy

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