Author
              
    
      
        
          
          
          Number of items: 43.
          
            
              
                
    
      
        
          
        
      
    
  
              
                
    
      
        
          
        
      
    
  
              
                
    
      
        
          
        
      
    
  
              
            
          
          
            
    
    
  
          
            
    
    
      
        2023
      
      
        
          
          
  
    
      
      
        Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model. (2023)
        
          
            
               Perezimor Etifa, 
            
               César Rodríguez, 
            
               Céline Harmanus, 
            
               Ingrid M. J. G. Sanders, 
            
               Igor A. Sidorov, 
            
               Olufunmilayo A. Mohammed, 
            
               Emily Savage, 
            
               Andrew R. Timms, 
            
               Jane Freeman, 
            
               Wiep Klaas Smits, 
            
               Mark H. Wilcox
                and
                
            
               Simon D. Baines
            
          
        
        
      
      
        
          
            
              
     
                          
            
          
        
        
      
    
  
  
        
      
    
  
          
            
    
    
  
          
            
    
    
      
        2019
      
      
        
          
          
  
    
      
      
        A laboratory-based evaluation of tube blocking and microbial risks associated with one blended enteral feed recipe. (2019)
        
          
            
               Angela Madden, 
            
               Simon Baines, 
            
               Simone Bothwell, 
            
               Elise Chen, 
            
               Shan Goh, 
            
               Lee Jerome, 
            
               Cara Sommariva-Nagle
                and
                
            
               Malgorzata Szychta
            
          
        
        
      
      
        
          
            
              
     High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates. (2019)
        
          
            
               Laura Tijerina-Rodrıguez, 
            
               Licet Villarreal-Trevino, 
            
               Simon Baines, 
            
               Rayo Morfin-Otero, 
            
               Adrian Camacho-Ortiz, 
            
               Samantha Flores-Trevino, 
            
               Hector Jesus Maldonado-Garza, 
            
               Elvira Garza-Gonzalez, 
            
               Eduardo Rodriguez-Noriega
                and
                
            
               Eduardo Rodrıguez-Noriega
                          
            
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates. (2019)
        
          
            
               Laura Tijerina-Rodrıguez, 
            
               Licet Villarreal-Trevino, 
            
               Simon Baines, 
            
               Rayo Morfin-Otero, 
            
               Adrian Camacho-Ortiz, 
            
               Samantha Flores-Trevino, 
            
               Hector Jesus Maldonado-Garza, 
            
               Elvira Garza-Gonzalez, 
            
               Eduardo Rodriguez-Noriega
                and
                
            
               Eduardo Rodrıguez-Noriega
            
          
        
        
      
      
        
          
            
              
     
                          
            
          
        
        
      
    
  
  
        
      
    
  
          
            
    
    
      
        2018
      
      
        
          
          
  
    
      
      
        Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria. (2018)
        
          
            
               Ian J Passmore, 
            
               Marine P M Letertre, 
            
               Mark D Preston, 
            
               Irene Bianconi, 
            
               Mark A Harrison, 
            
               Fauzy Nasher, 
            
               Harparkash Kaur, 
            
               Huynh A Hong, 
            
               Simon D Baines, 
            
               Simon M Cutting, 
            
               Jonathan R Swann, 
            
               Brendan W Wren
                and
                
            
               Lisa F Dawson
            
          
        
        
      
      
        
          
            
              
     Circulation of Highly Drug-Resistant Clostridium difficile Ribotypes 027 and 001 in Two Tertiary-Care Hospitals in Mexico. (2018)
        
          
            
               Adrian Adrian Martinez-Melendez, 
            
               Laura Tijerina-Rodrıguez, 
            
               Rayo Morfin-Otero, 
            
               Adrian Camacho-Ortiz, 
            
               Licet Villarreal-Trevino, 
            
               Hugo Sanchez-Alanıs, 
            
               Eduardo Rodrıguez-Noriega, 
            
               Simon Baines, 
            
               Samantha Flores-Trevino, 
            
               Hector Jesus Maldonado-Garza
                and
                
            
               Elvira Garza-Gonzalez
                          
            
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        Circulation of Highly Drug-Resistant Clostridium difficile Ribotypes 027 and 001 in Two Tertiary-Care Hospitals in Mexico. (2018)
        
          
            
               Adrian Adrian Martinez-Melendez, 
            
               Laura Tijerina-Rodrıguez, 
            
               Rayo Morfin-Otero, 
            
               Adrian Camacho-Ortiz, 
            
               Licet Villarreal-Trevino, 
            
               Hugo Sanchez-Alanıs, 
            
               Eduardo Rodrıguez-Noriega, 
            
               Simon Baines, 
            
               Samantha Flores-Trevino, 
            
               Hector Jesus Maldonado-Garza
                and
                
            
               Elvira Garza-Gonzalez
            
          
        
        
      
      
        
          
            
              
     
                          
            
          
        
        
      
    
  
  
        
      
    
  
          
            
    
    
  
          
            
    
    
      
        2015
      
      
        
          
          
  
    
      
      
        In vitro assessment of Clostridium difficile PCR ribotype 002: the most prevalent C. difficile ribotype in the United Kingdom. (2015)
        
          
            
               Simon Baines, 
            
               Iye Ameh, 
            
               Jane Freeman, 
            
               W N Fawley
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
     Antimicrobial resistance and reduced susceptibility in Clostridium difficile: potential consequences for induction, treatment, and recurrence of C. difficile infection. (2015)
        
          
            
               Simon D. Baines
                and
                
            
               M. H. Wilcox
                          
            
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        Antimicrobial resistance and reduced susceptibility in Clostridium difficile: potential consequences for induction, treatment, and recurrence of C. difficile infection. (2015)
        
          
            
               Simon D. Baines
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
     In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile. (2015)
        
          
            
               D. Corbett, 
            
               A. Wise, 
            
               S. Birchall, 
            
               P. Warn, 
            
               Simon D. Baines, 
            
               G. Crowther, 
            
               J. Freeman, 
            
               C. H. Chilton, 
            
               J. Vernon, 
            
               M. H. Wilcox
                and
                
            
               R. J. Vickers
            
          
        
        
      
      
        
          
            
              
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        SMT19969 as a treatment for Clostridium difficile infection : an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model. (2015)
        
          
            
               Simon D. Baines, 
            
               G. S. Crowther, 
            
               J. Freeman, 
            
               S. Todhunter, 
            
               R. Vickers
                and
                
            
               M. H. Wilcox
                          
            
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile. (2015)
        
          
            
               D. Corbett, 
            
               A. Wise, 
            
               S. Birchall, 
            
               P. Warn, 
            
               Simon D. Baines, 
            
               G. Crowther, 
            
               J. Freeman, 
            
               C. H. Chilton, 
            
               J. Vernon, 
            
               M. H. Wilcox
                and
                
            
               R. J. Vickers
            
          
        
        
      
      
        
          
            
              
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        SMT19969 as a treatment for Clostridium difficile infection : an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model. (2015)
        
          
            
               Simon D. Baines, 
            
               G. S. Crowther, 
            
               J. Freeman, 
            
               S. Todhunter, 
            
               R. Vickers
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
     Design, Synthesis and Antimicrobial Evaluation of the in vitro Efficacy of Novel Diketones. (2015)
        
          
            
               Rajesh Garikipati, 
            
               Olufunmilayo Mohammed, 
            
               Sharon Rossiter, 
            
               Simon Baines, 
            
               Jatinder Bassin
                and
                
            
               Madhu Goyal
                          
            
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        Design, Synthesis and Antimicrobial Evaluation of the in vitro Efficacy of Novel Diketones. (2015)
        
          
            
               Rajesh Garikipati, 
            
               Olufunmilayo Mohammed, 
            
               Sharon Rossiter, 
            
               Simon Baines, 
            
               Jatinder Bassin
                and
                
            
               Madhu Goyal
            
          
        
        
      
      
        
          
        
        
      
    
  
  
        
      
    
  
          
            
    
    
      
        2014
      
      
        
          
          
  
    
      
      
        Comparison of planktonic and biofilm-associated communities of Clostridium difficile and indigenous gut microbiota in a triple-stage chemostat gut model. (2014)
        
          
            
               Grace S. Crowther, 
            
               Caroline H. Chilton, 
            
               Sharie L. Todhunter, 
            
               Scott Nicholson, 
            
               Jane Freeman, 
            
               Simon D. Baines
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota. (2014)
        
          
            
               Grace S. Crowther, 
            
               Caroline H. Chilton, 
            
               Sharie L. Todhunter, 
            
               Scott Nicholson, 
            
               Jane Freeman, 
            
               Simon D. Baines
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
     
                          
            
          
        
        
      
    
  
  
        
      
    
  
          
            
    
    
      
        2013
      
      
        
          
          
  
    
      
      
        In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection. (2013)
        
          
            
               C. H. Chilton, 
            
               G. S. Crowther, 
            
               Simon D. Baines, 
            
               S. L. Todhunter, 
            
               J. Freeman, 
            
               H. H. Locher, 
            
               A. Athanasiou
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease. (2013)
        
          
            
               David W. Eyre, 
            
               A. Sarah Walker, 
            
               Jane Freeman, 
            
               Simon D. Baines, 
            
               Warren N. Fawley, 
            
               Caroline H. Chilton, 
            
               David Griffiths, 
            
               Alison Vaughan, 
            
               Derrick W. Crook, 
            
               Tim E. A. Peto
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
     Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection. (2013)
        
          
            
               Grace S Crowther, 
            
               Simon D. Baines, 
            
               Sharie L Todhunter, 
            
               Jane Freeman, 
            
               Caroline H Chilton
                and
                
            
               Mark H Wilcox
            
          
        
        
      
      
        
          
            
              
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        Evaluation of antimicrobial activity of ceftaroline against Clostridium difficile and propensity to induce C. difficile infection in an in vitro human gut model. (2013)
        
          
            
               Simon D. Baines, 
            
               Caroline H. Chilton, 
            
               Grace S. Crowther, 
            
               Sharie L. Todhunter, 
            
               Jane Freeman
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Evaluation of the effect of oritavancin on Clostridium difficile spore germination, outgrowth and recovery. (2013)
        
          
            
               C. H. Chilton, 
            
               J. Freeman, 
            
               Simon D. Baines, 
            
               G. S. Crowther, 
            
               S. Nicholson
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Mixed infection by Clostridium difficile in an in vitro model of the human gut. (2013)
        
          
            
               Simon D. Baines, 
            
               Grace S. Crowther, 
            
               Sharie L. Todhunter, 
            
               Jane Freeman, 
            
               Caroline H. Chilton, 
            
               Warren N. Fawley
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection. (2013)
        
          
            
               Grace S Crowther, 
            
               Simon D. Baines, 
            
               Sharie L Todhunter, 
            
               Jane Freeman, 
            
               Caroline H Chilton
                and
                
            
               Mark H Wilcox
            
          
        
        
      
      
        
          
            
              
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        Evaluation of antimicrobial activity of ceftaroline against Clostridium difficile and propensity to induce C. difficile infection in an in vitro human gut model. (2013)
        
          
            
               Simon D. Baines, 
            
               Caroline H. Chilton, 
            
               Grace S. Crowther, 
            
               Sharie L. Todhunter, 
            
               Jane Freeman
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Evaluation of the effect of oritavancin on Clostridium difficile spore germination, outgrowth and recovery. (2013)
        
          
            
               C. H. Chilton, 
            
               J. Freeman, 
            
               Simon D. Baines, 
            
               G. S. Crowther, 
            
               S. Nicholson
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Mixed infection by Clostridium difficile in an in vitro model of the human gut. (2013)
        
          
            
               Simon D. Baines, 
            
               Grace S. Crowther, 
            
               Sharie L. Todhunter, 
            
               Jane Freeman, 
            
               Caroline H. Chilton, 
            
               Warren N. Fawley
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        2011
      
      
        
          
          
  
    
      
      
        Evaluation of linezolid for the treatment of Clostridium difficile infection caused by epidemic strains using an in vitro human gut model. (2011)
        
          
            
               Simon D. Baines, 
            
               Alan R. Noel, 
            
               Grace S. Huscroft, 
            
               Sharie L. Todhunter, 
            
               Rachael O'Connor, 
            
               Joanne K. Hobbs, 
            
               Jane Freeman, 
            
               Andy M. Lovering
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Nitazoxanide is active against Clostridium difficile strains with reduced susceptibility to metronidazole. (2011)
        
          
            
               Jane Freeman, 
            
               Simon D. Baines, 
            
               Sharie L. Todhunter, 
            
               Grace S. Huscroft
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Short-term genomic stability of Clostridium difficile within patients and a gut model. (2011)
        
          
            
               D. W. Eyre, 
            
               C. Ip, 
            
               R. M. Harding, 
            
               J. Freeman, 
            
               Simon D. Baines, 
            
               W. N. Fawley, 
            
               S.D. Walker, 
            
               D. W. Crook, 
            
               T. E. A. Peto
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        Efficacy of novel antimicrobial agent SMT-19969 (SMT) against simulated Clostridium difficile infection in an in vitro human gut model. (2011)
        
          
            
               Simon D. Baines, 
            
               J. Freeman, 
            
               Grace S. Huscroft, 
            
               Sharie L. Todhunter, 
            
               M. H. Wilcox
                and
                
            
               R. Vickers
            
          
        
        
      
      
        
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        SMT19969 – a novel antibiotic for C. difficile : Clostridium difficile growth inhibition, spectrum of activity and resistance development. (2011)
        
          
            
               R. Vickers, 
            
               J. Tinsley, 
            
               R. Storer, 
            
               F. Wilson, 
            
               C. Dorgan, 
            
               S. Wren, 
            
               M. H. Wilcox, 
            
               Simon D. Baines
                and
                
            
               J. Freeman
            
          
        
        
      
      
        
          
        
        
      
    
  
  
        
          
          
  
    
      
      
        SASP: targeted delivery to Gram-negative pathogens. (2011)
        
          
            
               H. Wang, 
            
               K. Hatzixanthis, 
            
               A. Barnard, 
            
               R. Shah, 
            
               E. Saveri, 
            
               K. Pitts, 
            
               D. Piwowarczyk, 
            
               G. Patil, 
            
               Simon D. Baines, 
            
               A. Wilkinson
                and
                
            
               H. Fairhead
            
          
        
        
      
      
        
          
        
        
      
    
  
  
        
      
    
  
          
            
    
    
  
          
            
    
    
      
        2009
      
      
        
          
          
  
    
      
      
        Activity of vancomycin against epidemic Clostridium difficile strains in a human gut model. (2009)
        
          
            
               Simon D. Baines, 
            
               Rachel O'Connor, 
            
               Katie Saxton, 
            
               Jane Freeman
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Characterization of the sporulation initiation pathway of Clostridium difficile and its role in toxin production. (2009)
        
          
            
               Sarah Underwood, 
            
               Shuang Guan, 
            
               Vinod Vijayasubhash, 
            
               Simon D. Baines, 
            
               Luke Graham, 
            
               Richard J. Lewis, 
            
               M. H. Wilcox
                and
                
            
               Keith Stephenson
            
          
        
        
      
      
        
          
            
              
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        Effects of exposure of Clostridium difficile PCR ribotypes 027 and 001 to fluoroquinolones in a human gut model. (2009)
        
          
            
               Katie Saxton, 
            
               Simon D. Baines, 
            
               Jane Freeman, 
            
               Rachael O'Connor
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Mecillinam : a low-risk antimicrobial agent for induction of Clostridium difficile infection in an in vitro human gut model. (2009)
        
          
            
               Simon D. Baines, 
            
               Rachael O'Connor, 
            
               Grace Huscroft, 
            
               Katie Saxton, 
            
               Jane Freeman
                and
                
            
               Mark H Wilcox
            
          
        
        
      
      
        
          
            
              
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        Tolevamer is not efficacious in the neutralization of cytotoxin in a human gut model of Clostridium difficile infection. (2009)
        
          
            
               Simon D. Baines, 
            
               Jane Freeman
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        2008
      
      
        
          
          
  
    
      
      
        Comparison of oritavancin versus vancomycin as treatments for clindamycin-induced Clostridium difficile PCR ribotype 027 infection in a human gut model. (2008)
        
          
            
               Simon D. Baines, 
            
               Rachael O'Connor, 
            
               Katie Saxton, 
            
               Jane Freeman
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        Emergence of reduced susceptibility to metronidazole in Clostridium difficile. (2008)
        
          
            
               Simon D. Baines, 
            
               Rachael O'Connor, 
            
               Jane Freeman, 
            
               Warren N Fawley, 
            
               Celine Harmanus, 
            
               Paola Mastrantonio, 
            
               Ed J. Kuijper
                and
                
            
               M. H. Wilcox
            
          
        
        
      
      
        
          
            
              
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        In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin. (2008)
        
          
            
               Rachael O'Connor, 
            
               Simon D. Baines, 
            
               Jane Freeman
                and
                
            
               Mark H. Wilcox
            
          
        
        
      
      
        
          
            
              
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