UH Research Archive: Recent submissions
Now showing items 6421-6440 of 11145
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The acute and the long-term effects of nigral lipopolysaccharide administration on dopaminergic dysfunction and glial cell activation
(2005-07)Sustained reactive microgliosis may contribute to the progressive degeneration of nigral dopaminergic neurons in Parkinson's disease (PD), in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exposed human and in non-human ... -
H-1 NMR study of the conformation and absolute stereochemistry of two spirocyclic NK-1 antagonists
(2005-08)The binding affinities at the human NK-1 receptor of two spirocyclic compounds were found to be similar despite being epimeric at a key stereocentre. This unexpected result prompted a thorough investigation of the solution ... -
Age-associated changes in protein oxidation and proteasome activities in rat brain: Modulation by antioxidants
(2005-10-21)The free radical theory of ageing postulates that age-associated neurodegeneration is caused by an imbalance between pro-oxidants and antioxidants resulting in oxidative stress. The current study showed regional variation ... -
Unilateral pallidotomy in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets exhibiting levodopa-induced dyskinesia
(2005-09)Pallidotomy paradoxically reduces the intensity of levodopa-induced dyskinesia without worsening motor symptoms. The reasons for this are not clear and no experimental study has investigated this phenomenon. The objective ... -
Generalizing Darwinism to social evolution : Some early attempts
(2005-12-01)The article focuses on the early attempts of generalizing Darwinism to social evolution. In early literature, definitions of the core concepts of a generalized Darwinism are absent. Earlier writings failed to identify the ... -
Adhesion of Pasteuria penetrans to the cuticle of root-knot nematodes (Meloidogyne spp.) inhibited by fibronectin : A study of electrostatic and hydrophobic interactions
(1996-05)Pasteuria penetrans is a bacterium with the potential to control plant-parasitic nematode populations; the mechanism of spore adhesion, however, is poorly understood. Attachment assays were performed in media supplemented ... -
Interaction between fenbendazole and piperonyl butoxide : pharmacokinetic and pharmacodynamic implications
(1996-07)The effect of the cytochrome P450 inhibitor, piperonyl butoxide on the pharmacokinetics and anthelmintic efficacy of the benzimidazole compound fenbendazole was studied in sheep and goats. Pretreatment of goats with the ... -
Protein binding and in vitro serum thromboxane B2 inhibition by flunixin meglumine and meclofenamic acid in dog, goat and horse blood
(1996-07)lunixin was highly protein bound in the serum of dogs (92.2 per cent), gents (84.8 per cent) and horses (86.9 per cent). Meclofenamic acid was also highly protein bound, although there were larger differences between the ... -
Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats
(1997)Phenylbutazone was administered intravenously and orally to six goats as a single dose of 4.4 mg/kg and its disposition and bioavailability and the disposition of its active metabolite, oxyphenbutazone, in plasma were ... -
Overview of the environmental impacts of agriculture in the UK
(1997-06-01)This review has been necessary to bring together and interpret much of the diverse literature relating to the key areas of environmental impact associated with agriculture. The main environmental impacts of agriculture in ... -
Noradrenergic mechanisms in the prefrontal cortex.
(1997)There is growing evidence that noradrenergic inputs to the prefrontal cortex (PFC) play an important role in regulating its function. This paper reviews the pharmacological control of noradrenaline (NA) release in this ... -
Direct somatic embryogenesis and plant regeneration from mature sugarbeet (Beta vulgaris L.) zygotic cotyledons
(1997)An in vitro protocol has been developed for direct somatic embryogenesis of zygotic cotyledons from mature sugarbeet (Beta vulgaris L.) embryos. Explants were sequentially cultured on modified Murashige and Skoog (MS) ... -
Effects of temperature, cultivar and isolate on the incubation period of white leaf spot (Mycosphaerella capsellae) on oilseed rape (Brassica napus)
(1997-04)When leaves of oilseed rape (cv. Cobra) were inoculated with conidial suspensions of Mycosphaerella capsellae (white leaf spot) and incubated in controlled environments, the lag period from inoculation to the appearance ... -
Effect of wind on the dispersal of oospores of Peronosclerospora sorghi from sorghum
(1997-06)The effect of wind on the dispersal of oospores of Peronosclerospora sorghi, cause of sorghum downy mildew (SDM) is described. The oospores are produced within the leaves of aging, systemically infected sorghum plants. ... -
Ecotoxicology and residues of anthelmintic compounds
(1997-11)Anthelmintics and endectocides used for the treatment and prophylaxis of Ostertagia sp. in ruminants include benzimidazoles, levamisole, morantel and the avermectins and milbemycins. Most of these agents are excreted to ... -
The genetic basis of resistance to Ostertagia circumcincta in lambs
(1997-09)The relationship between Ostertagia (Teladorsagia) circumcincta and sheep is one of the best understood host-parasite relationships in any species. The key components of resistance have been quantified, the extent of genetic ... -
Insect injury to linseed in south-east England
(1997-11)Pests were monitored on linseed crops in Hertfordshire, Cambridgeshire and Bedfordshire from 1987 to 1990. Adult flea beetles (Aphthona euphorbiae and Longitarsus parvulus) caused severe injury to seedlings; their numbers ... -
Influence of target characteristics on the amount of water splashed by impacting drops
(1997-11-15)Experiments were done to investigate the influence of drop diameter on the efficiency of the splash process, using a rain tower and different types of target (glass, water films, healthy and/or diseased oilseed rape leaves ... -
Response of salt-stressed strawberry plants to supplementary calcium nitrate and/or potassium nitrate
(2003)A pot experiment was carried out with two strawberry (Fragaria x ananassa Duch) cultivars, Oso Grande and Camarosa in sand culture to investigate the effects of supplementary calcium and potassium nitrate to plants grown ...