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Can simvastatin improve erectile function and health-related quality of life in men aged ≥40 years with erectile dysfunction? : Results of the Erectile Dysfunction and Statins Trial [ISRCTN66772971]
(2013-01-29)
To evaluate the effectiveness and cost-effectiveness of simvastatin on erectile function and health-related quality of life in men aged ≥40 years with erectile dysfunction (ED).
Measuring and modelling occupancy time in NHS continuing healthcare
(2011)
Due to increasing demand and financial constraints, NHS continuing healthcare systems seek to find better ways of forecasting demand and budgeting for care. This paper investigates two areas of concern, namely, how long ...
Developing a dyadic OPTION scale to measure perceptions of shared decision making
(2010)
Our aim was to develop a measurement which enables research into the interdependent nature of clinical encounters. The prime objective was to develop an instrument capable of assessing the extent to which patients have ...
Revascularization versus medical therapy for renal-artery stenosis
(2009)
Atherosclerotic renovascular disease is a common condition with a rate of death of about 16% per year, largely from associated cardiovascular disease.1-3 Stenosis of the renal artery is associated with both hypertension ...
Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons
(2008)
Cannabinoid receptor 2 (CB2) agonists provide the potential for treating chronic pain states without CNS effects associated with CB1 receptor activation. Animal models suggest that they act mainly via non-neuronal cells, ...
Electronic prescribing reduced prescribing errors in a pediatric renal outpatient clinic
(2008)
To assess the effect of an electronic prescribing (EP) system on the incidence and type of prescribing errors and the number of error-free visits.
Colorectal tumor vascularity: quantitative assessment with multidetector CT--do tumor perfusion measurements reflect angiogenesis?
(2008)
To establish the relationships between quantitative perfusion computed tomography (CT) parameters-specifically, primary tumor blood flow, blood volume, transit time, and permeability surface-area product-and immunohistologic ...
Proteomic biomarkers of peripheral blood mononuclear cells obtained from postmenopausal women undergoing an intervention with soy isoflavones
(2007-11)
The incidence of cardiovascular diseases increases after menopause, and soy consumption is suggested to inhibit disease development.
Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide
(2006-06)
Homocysteine and asymmetric dimethylarginine (ADMA) affect nitric oxide (NO) concentration, thereby contributing to cardiovascular disease (CVD). Both amino acids can be reduced in vivo by estrogen. Variation in the estrogen ...
Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women : interactions with genotype and equol production
(2006-03)
The hypocholesterolemic effects of soy foods are well established, and it has been suggested that isoflavones are responsible for this effect. However, beneficial effects of isolated isoflavones on lipid biomarkers of ...