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Browsing by Author "Centre for Lifespan and Chronic Illness Research"
Now showing items 121-140 of 153
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Relative effects of different non-vitamin K antagonist oral anticoagulants on global thrombotic status in atrial fibrillation
Farag, Mohamed; Niespialowska-Steuden, Maria; Okafor, Osita; Artman, Benjamin; Srinivasan, Manivannan; Khan, Arif; Sullivan, Keith; Wellsted, David; Gorog, Diana A (2016-10-02)Non-vitamin K antagonist oral anticoagulants (NOACs) reduce the risk of thromboembolism in patients with atrial fibrillation (AF). There has been no head-to-head comparison of the effect of these agents on ex vivo thrombotic ... -
Relative hand skill predicts academic ability: global deficits at the point of hemispheric indecision
Crow, T.J.; Crow, L.R.; Done, D.J.; Leask, S.J. (1998)Population variation in handedness (a correlate of cerebral dominance for language) is in part genetic and, it has been suggested, its persistence represents a balanced polymorphism with respect to cognitive ability. This ... -
Residual renal function improves outcome in incremental haemodialysis despite reduced dialysis dose
Vilar, Enric; Wellsted, D.; Chandna, S.M.; Greenwood, R.N.; Farrington, Ken (2009-02-24)Background and Methods. The importance of residual renal function is well recognized in peritoneal dialysis but its role in haemodialysis (HD) has received much less attention. We studied 650 incident patients in our ... -
Risk of adult schizophrenia and its relationship to childhood IQ in the 1958 British birth cohort.
Schulz, Joerg; Sundin, Josefin; Leask, S.K.; Done, D.J. (2014)Background: An inverse relationship between risk of schizophrenia and premorbid IQ is a robust empirical finding. Cognitive impairment may be a core feature of schizophrenia in addition to the clinical symptoms that have ... -
The role of the general practitioner in the community care of people with HIV infection and AIDS : a comparative study of high- and low-prevalence areas in England
King, M.; Petchey, R.; Singh, S.; Wright, L.; Raab, J.; Farnsworth, W.; Williams, J.; Friedli, K. (1998-05)Background. Policy for the care of people suffering from HIV and AIDS has changed over the past decade. Schemes for shared primary and secondary care have been met with varying success, and patients may be reluctant to ... -
Scan-time reduction using noise-matched images in 2- and 3-dimensional bismuth germanate PET/CT : clinical study in head and neck cancer
Sanghera, Bal; Lowe, Gerry; Wellsted, D.; Lowe, John; Chambers, Jane; Wong, WaiLup (2009)We quantitatively and qualitatively investigated 2-dimensional (2D) and 3-dimensional (3D) imaging with scan-time reduction in 14 patients with 17 lesions, who had known or suspected head and neck cancer, using a bismuth ... -
School Years Developmental Journal
Mengoni, Silvana; Oates, John (National Children's Bureau: London, 2013)The School Years Developmental Journal is designed to help parents, young people, teachers and other practitioners record, celebrate and support learning and development. It also helps everyone to share information, ... -
Screening for depression while patients dialyse : an evaluation
Chilcot, J.; Wellsted, D.; Farrington, Ken (2008)Background: The lack of routine depression screening among the haemodialysis (HD) population may contribute to depression being under-recognised. While screening patients could be beneficial, the optimum screening procedure ... -
Secular Changes in Clinical Features at Presentation of Rheumatoid Arthritis : Increase in Comorbidity But Improved Inflammatory States
Nikiphorou, Elena; Norton, Sam; Carpenter, Lewis; Dixey, Josh; Andrew Walsh, David; Kiely, Patrick; Young, Adam; on behalf of the Early Rheumatoid Arthritis Study and the Early Rheumatoid Arthritis Network Cohorts (2017-01-31)Objective: To examine secular trends in demographics, clinical manifestations, and comorbidity on first presentation of rheumatoid arthritis (RA) prior to disease-modifying antirheumatic drug treatment. Methods: A total ... -
Self-management for people with long-term neurological conditions
Chaplin, Hema; Hazan, Jill; Wilson, Patricia (2012-05)Although English government policy has encouraged the implementation of self-management programmes in services for people with long-term conditions, the evidence for their efficacy has been limited. People with long-term ... -
Self-management interventions for epilepsy in people with intellectual disabilities: A Scoping Review
Dannenberg, Michelle; Mengoni, Silvana; Gates, Robert; Durand, Marie-Anne (2016-10-01)Purpose People with intellectual disabilities (ID) experience higher incidences of chronic health conditions, poorer health outcomes, and increased risk of premature death. Epilepsy is 20 times more common in people with ... -
Semantic memory impairment in schizophrenia : Deficit in storage or access of knowledge?
Doughty, O.J.; Done, D.J.; Lawrence, V.A.; Al-Mousawi, A.; Ashaye, K. (2008)This study evaluates whether patients with schizophrenia have a degraded memory store for semantic knowledge. 20 patients with a chronic history of schizophrenia and evidence of cognitive impairment were selected, since ... -
Shear-induced global thrombosis test of native blood: Pivotal role of ADP allows monitoring of P2Y12 antagonist therapy
Saraf, S.; Wellsted, D.; Sharma, S.; Gorog, D.A. (2009)Background: It is claimed that in shear-induced platelet function tests, shear-stress is the sole agonist causing platelet activation and resultant thrombosis. However, the fact that red blood cells (RBC) are essential to ... -
Simvastatin improves the sexual health-related quality of life in men aged 40 years and over with erectile dysfunction : Additional data from the Erectile Dysfunction and Statin trial
Trivedi, Daksha; Wellsted, D.; Collard, Jade; Kirby, Michael (2014-03-05)Background: Erectile dysfunction is prevalent in men over 40 years, affecting their quality of life and that of their partners. The aims of this study were:a)To evaluate the internal reliability of the male erectile ... -
The size, burden and cost of disorders of the brain in the UK
Fineberg, Naomi; Haddad, Peter M.; Carpenter, Lewis; Gannon, Brenda; Sharpe, Rachel; Young, Allan H.; Joyce, Eileen; Rowe, James; Wellsted, D.; Nutt, David J.; Sahakian, Barbara J. (2013-09)Aim: The aim of this paper is to increase awareness of the prevalence and cost of psychiatric and neurological disorders (brain disorders) in the UK. Method: UK data for 18 brain disorders were extracted from a systematic ... -
Snacking patterns according to location among Northern Ireland children
Kerr, Maeve A.; Mccrorie, Tracy A.; Rennie, Kirsten L.; Wallace, Julie M. W.; Livingstone, M. Barbara E. (2010-05)Objective:To examine the influence of location on snack intake among Northern Ireland (NI) children aged 5-8 years. Methods: Dietary intake was assessed by 7-day weighed dietary records. Parents/children self defined type ... -
Snacking patterns among adolescents: a comparison of type, frequency and portion size between Britain in 1997 and Northern Ireland in 2005
Kerr, M.A.; Rennie, K.L.; McCaffrey, T.M.; Wallace, J.M.; Hannon-Fletcher, M.P.; Livingstone, M.B.E. (2009)Despite the potential link between snack food intake and obesity and the reportedly high prevalence of snacking among adolescents, adolescent snack food patterns (types of foods consumed, frequency and portion size) have ... -
"Sometimes, it just stops me from doing anything”: A qualitative exploration of epilepsy management in people with intellectual disabilities and their carers
Mengoni, Silvana; Gates, Robert; Parkes, Georgina; Wellsted, David; Barton, Garry; Ring, Howard; Khoo, Mary Ellen; Monji-Patel, Deela; Friedli, Karin; Zia, Asif; Durand, Marie-Anne (2016-10-11)Epilepsy affects 1 in 5 people with an intellectual disability (ID), but little is known about their experiences of living with epilepsy. A qualitative study was conducted to investigate the impact and management of epilepsy ... -
A study of sertraline in dialysis (ASSertID) : a protocol for a pilot randomised controlled trial of drug treatment for depression in patients undergoing haemodialysis
Friedli, Karin; Almond, Michael; Day, Clara; Chilcot, Joseph; Gane, Maria da Silva; Davenport, Andrew; Guirguis, Ayman; Fineberg, Naomi; Spencer, Benjamin; Wellsted, D.; Farrington, Ken (2015-10-26)BACKGROUND: The prevalence of depression in people receiving haemodialysis is high with estimates varying between 20 and 40 %. There is little research on the effectiveness of antidepressants in dialysis patients with the ... -
The synchronous relationship between somatic symptoms and psychological distress in early rheumatoid arthritis : findings from a prospective observational study.
Norton, Sam; Sacker, Amanda; Done, D.J.; Young, Adam (2012-05)The longitudinal relationship between somatic symptoms and psychological distress in rheumatoid arthritis (RA) is often assumed to be strong and bidirectional. However, despite previous research identifying strong ...