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Browsing by Author "Ingram, M.J."
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Design, synthesis and characterisation of captopril prodrugs for enhanced percutaneous absorption
Moss, G.P.; Gullick, D.R.; Alexander, C.; Ingram, M.J.; Smart, J.D.; Pugh, W.J. (2006)Most drugs are designed primarily for oral administration, but the activity and stability profiles desirable for this route often make them unsuitable for transdermal delivery. We were therefore interested in designing ... -
Metabolism of captopril carboxyl ester derivatives for percutaneous absorption
Gullick, D.R.; Ingram, M.J.; Pugh, W.J.; Cox, P.A.; Gard, P.; Smart, J.D.; Moss, G.P. (2009)To determine the metabolism of captopril n-carboxyl derivatives and how this may impact on their use as transdermal prodrugs. The pharmacological activity of the ester derivatives was also characterised in order to compare ... -
Pharmacy student perceptions of educational media tools
Ingram, M.J.; Sagoe, L.A.; Sosabowski, M.H.; Moss, G.P.; Long, A.J. (2007) -
A potential anti-implantation and spermicidal strategy : Putative derivatives of nonoxynol-9 and anti-inflammatory agents and their spermicidal activity
Ingram, M.J.; Zeller, E.; Moss, G.P.; Hall, C.E. (2006)We report the synthesis of novel ester derivatives of nonoxynol-9, an approved spermicidal agent, using the non-steroidal inflammatory drugs (NSAIDs) ibuprofen and indomethacin. Indomethacin has previously been shown to ...