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Browsing by Author "Stair, Jacqueline"
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A Design-of-Experiments Approach to Developing Thermoresponsive Gelators From Complex Polymer Mixtures
Kirton, Stewart; Stair, Jacqueline; Abou Shamat, Mohamad; Calvo-Castro, Jesus; Cook, Michael T. (2020-10-13)This study investigated the effects of additives on the properties of poloxamer (P) 407 thermogels, employing a design-of-experiments (DoE) approach. P407 is a thermoresponsive triblock copolymer that exhibits a solution ... -
Detection of Newly Emerging Psychoactive Substances Using Raman Spectroscopy and Chemometrics
Calvo-Castro, Jesus; Guirguis, Amira; Samaras, Eleftherios; Zloh, Mire; Kirton, Stewart; Stair, Jacqueline (2018-09-12)A novel approach for the identification of New Psychoactive Substances (NPS) by means of Raman spectroscopy coupled with Principal Components Analysis (PCA) employing the largest dataset of NPS reference materials to date ... -
Determination of Cu2+ ions release rate from antimicrobial copper bearing stainless steel by joint analysis using ICP-OES and XPS
Ren, Ling; Chong, J.; Loya, Adil; Kang, Q.; Stair, Jacqueline; Nan, L.; Ren, Guogang (2015-08-30)Antibacterial Cu bearing stainless steels (CuSS) have been developed recently and their performance has attracted significant attention widely in biomedical, healthcare and environmental facilities in cross-disciplines. ... -
Drowning in Diversity? A systematic way of clustering a representative set of new psychoactive substances
Zloh, Mire; Samaras, Eleftherios; Calvo-Castro, Jesus; Guirguis, Amira; Stair, Jacqueline; Kirton, Stewart (2017-11-17)New psychoactive substances (NPS) can be generally described as a set of compounds that have been designed to mimic the effects of illegal recreational drugs, but are not subject to restriction or control with respect to ... -
Emergence and identification of new products of designer drug products from the internet
Assi, Sulaf; Fergus, Suzanne; Stair, Jacqueline; Corazza, Ornella; Schifano, Fabrizio (2011)Designer drugs represent a rapidly expanding phenomenon particularly facilitated by their Internet availability. These drugs are continuously emerging as analogues of controlled substances (amfetamine, aminoindane, cathinone, ... -
Identification of new psychoactive substances (NPS) using handheld Raman Spectroscopy employing both 785 and 1064 nm laser sources
Guirguis, Amira; Girotto, Sarah; Berti, Benedetta; Stair, Jacqueline (2017-04-01)The chemical identification of new psychoactive substances (NPS) in the field is challenging due not only to the plethora of substances available, but also as a result of the chemical complexity of products and the chemical ... -
Identification of new psychoactive substances using Raman spectroscopy: handheld and computational approaches.
Guirguis, Amira; Kirton, Stewart; Zloh, Mire; Samaras, Eleftherios; Girotto, Sarah; Berti, Benedetta; Stair, Jacqueline (Research and Advances in Psychiatry, 2016-05)At this conference, I gave a presentation on the identification of new psychoactive substances using handheld Raman spectroscopy and chemometrics. -
Immobilized peptides/amino acids on solid supports for metal remediation
Malachowski, L.; Stair, Jacqueline; Holcombe, James A. (2004-04)Recently, a significant amount of work has focused on metal binding by natural systems for various applications. This review will focus on the utility of amino acids, short peptides, and proteins that have been immobilized ... -
Intended and Unintended Use of Cathinone Mixtures
Guirguis, Amira; Corkery, John; Stair, Jacqueline; Kirton, Stewart; Zloh, Mire; Schifano, Fabrizio (2017-06-28)Introduction: Cathinones are one of the most popular categories of new psychoactive substances (NPS) consumed. Cathinones have different pharmacological activities and receptor selectivity for monoamine transporters based ... -
Layered Polyelectrolyte Films as Selective, Ultrathin Barriers for Anion Transport
Stair, Jacqueline (2000-06-23)Synthesis of high-flux composite membranes requires methods for deposition of ultrathin, defect-free films on highly permeable supports. Layer-by-layer deposition of polyelectrolytes on porous alumina (0.02 µm pore diameter) ... -
Mephedrone (4-methylmethcathinone; 'meow meow') : chemical, pharmacological and clinical issues
Schifano, Fabrizio; Albanese, Antonio; Fergus, Suzanne; Stair, Jacqueline; Deluca, Paolo; Corazza, Ornella; Davey, Zoe; Corkery, John; Siemann, Holger; Scherbaum, Norbert; Farre', Magi'; Torrens, Marta; Demetrovics, Zsolt; Ghodse, A. Hamid; ReDNet Res Grp, Psychonaut Web Mapping (2011)Recently, those substances deriving from the active ingredient of the Khat plant, cathinone, have been rising in popularity. Indeed, 4-methylmethcathinone (mephedrone; 'meow meow' and others) has been seen by some as a ... -
Metal remediation and preconcentration using immobilized short-chain peptides composed of aspartic acid and cysteine
Holcombe, James A.; Stair, Jacqueline (2005-08)Short-chain peptides (two and seven residues) consisting of a glycine (Gly) attachment group and various combinations of cysteine (Cys) and/or aspartic acid (Asp) were synthesized by Fmoc solid phase peptide synthesis ... -
Method Development for the Determination of Elements in Hypericum perforatum L. (St John’s wort) Herb and Preparations using ICP-OES and Microwave Digestion
Owen, Jade; Evans, Sara; Guirguis, Amira; Kellett, Kathryn; Stair, Jacqueline (2017-05-31)Objectives: A method was developed to analyze St John's wort (Hypericum perforatum L.) herb and preparations using inductively coupled plasma-optical emission spectroscopy (ICP-OES) to determine the quantity of 11 elements ... -
Modifying the Properties of Thermogelling Poloxamer 407 Solutions through Covalent Modification and the Use of Polymer Additives
Abou Shamat, Mohamad; Calvo-Castro, Jesus; Stair, Jacqueline; Cook, Michael (2019-07-22)Thermoresponsive polymers that undergo sol–gel transition in a physiological temperature range have applications in biomedical science. Poloxamer 407 (P407) is commonly used as thermogelling material and has been approved ... -
Molecular dynamics simulation on surface modification of quantum scaled CuO nano-clusters to support their experimental studies
Loya, Adil; Stair, Jacqueline; Uddin, Farid; Ren, Guogang (2022-10-05)Interest in nanoparticle modification using functional chemicals has increased rapidly, as it allows more freedom of physiochemical tuning of the nanoparticle’s surface into biomedically oriented and designated properties. ... -
Novel psychoactive substances (NPS) – knowledge and experiences of drug users from Hungary, Poland, the UK and the USA
Pisarska, Agnieszka; Deluca, Paolo; Demetrovics, Zsolt; Corkery, John; Moskalewicz, Jacek; ReDNet Group; Corazza, Ornella; Corkery, John; Stair, Jacqueline; Fergus, Suzanne; Pezzolesi, Cinzia; Schifano, Fabrizio (2020-02-18)Dopamine D 3 receptor partial agonists represent a new generation of atypical antipsychotics. Cariprazine, which has received centralized market authorization from the European Medicines Agency in 2017 for the treatment ... -
Nowe substancje psychoaktywne : potrzeby informacyjne młodzieży I profesjonalistów
Pisarska, Agnieszka; Moskalewicz, Jacek; Corazza, Ornella; Assi, Sulaf; Simonato, Pierluigi; Corkery, John; Demetrovics, Zsolt; Stair, Jacqueline; Fergus, Suzanne; Pezzolesi, Cinzia; Pasinetti, Manuela; Deluca, Paolo; Drummond, Colin; Blaszko, Ursula; Mervo, Barbara; Di Furia, Lucia; Farre, Magi; Flesland, Liv; Shapiro, Harry; Siemann, Holger; Skutle, Arvid; Torrens, Marta; Sambola, Farran; van der Kreeft, Peer; Scherbaum, Norbert; Schifano, Fabrizio (2013-06)(translated from Polish) The study conducted in the frame of the RedNet project among health professionals dealing with drug users (N=124) and youth population (N=716) was aimed at assessment of the level of knowledge about ... -
NPS detection in Prison: a Systematic Literature Review of Use, Drug Form, and Analytical Approaches
Stair, Jacqueline; Vaccaro, Giorgia; Guirguis, Amira; Kirton, Stewart; Massariol, Anna (2022-03-30)This paper presents a systematic literature review on the detection of new psychoactive substances (NPS) in prison settings. It includes the most frequently reported NPS classes, the routes and forms used for smuggling, ... -
Phenomenon of new drugs on the Internet : the case of ketamine derivative methoxetamine
Corazza, Ornella; Schifano, Fabrizio; Simonato, Pierluigi; Fergus, Suzanne; Assi, Sulaf; Stair, Jacqueline; Corkery, John; Trincas, Giuseppina; Deluca, Paolo; Davey, Zoe; Blaszko, Ursula; Demetrovics, Zsolt; Moskalewicz, Jacek; Enea, Aurora; di Melchiorre, Giuditta; Mervo, Barbara; Di Furia, Lucia; Farre, Magi; Flesland, Liv; Pasinetti, Manuela; Pezzolesi, Cinzia; Pisarska, Agnieszka; Shapiro, Harry; Siemann, Holger; Skutle, Arvid; Enea, Aurora; di Melchiorre, Giuditta; Sferrazza, Elias; Torrens, Marta; van der Kreeft, Peer; Zummo, Daniela; Scherbaum, Norbert (2012)On the basis of the material available both in the scientific literature and on the web, this paper aims to provide a pharmacological, chemical and behavioural overview of the novel compound methoxetamine. This is a ... -
Presence of metals in herbal extracts
Guirguis, Amira; Owen, Jade; Stair, Jacqueline (2012-11-06)Do metals from raw herbs transport into herbal preparations during manufacture? Amira Guirguis and colleagues take a look at the issue using St John’s wort as an example.