Now showing items 31-40 of 356
Relay bioavailability and toxicity of isometamidium residues : a model for human risk assessment
The bioavailability and potential toxicity of the residues of the antitrypanosomal drug isometamidium (ISMM) in bovine tissues were investigated in male Sprague-Dawley rats. They were allowed to feed for 7 and 21 days on ...
Current models in pharmacokinetics : applications in veterinary pharmacology
Major advances in developing models for pharmacokinetic studies have been made in recent years, and different approaches can now be employed. These include the use of (1) compartmental models, (2) non-compartmental models, ...
A Lateral Cap model of microtubule dynamic instability
The co-existence and interconversion of growing and shrinking microtubules have been termed ‘dynamic instability’, and have been directly observed to occur under a variety of conditions in vitro and in vivo. Previous ...
Flunixin pharmacokinetics and serum thromboxane inhibition in the dog
Flunixin meglumine administered orally to beagle dogs at doses of 0.55, 1.10 or 1.65 mg/kg bodyweight was rapidly absorbed to produce maximum mean plasma concentrations of 2.40 +/- 0.70, 4.57 +/- 1.12 and 7.42 +/- 2.07 ...
Corridor or blind alley? The A1M Herts corridor consortium
Local authority intervention in the local economy has proliferated in recent years and is not, as much work suggests, confined to large Labour controlled authorities coping with inner city problems and/or declining heavy ...
Effect of an antimuscarinic drug on the plasma pepsinogen activity of sheep infected with Ostertagia circumcincta
The antimuscarinic drug atropine caused a marked fall in plasma pepsinogen values of sheep with burdens of Ostertagia circumcincta and this response was greater in animals which had higher plasma pepsinogen values before ...